2hhh

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Template:STRUCTURE 2hhh

Contents

Crystal structure of kasugamycin bound to the 30S ribosomal subunit

Template:ABSTRACT PUBMED 16998488

About this Structure

2hhh is a 21 chain structure of Ribosomal protein S10, Ribosomal protein S11, Ribosomal protein S12, Ribosomal protein S13, Ribosomal protein S15, Ribosomal protein S17, Ribosomal protein S2, Ribosomal protein S20, Ribosomal protein S3, Ribosomal protein S4 and Ribosomal protein THX with sequence from Thermus thermophilus hb8. Full crystallographic information is available from OCA.

See Also

Reference

  • Schluenzen F, Takemoto C, Wilson DN, Kaminishi T, Harms JM, Hanawa-Suetsugu K, Szaflarski W, Kawazoe M, Shirouzu M, Nierhaus KH, Yokoyama S, Fucini P. The antibiotic kasugamycin mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation. Nat Struct Mol Biol. 2006 Oct;13(10):871-8. Epub 2006 Sep 24. PMID:16998488 doi:10.1038/nsmb1145

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