Complexin

From Proteopedia

Revision as of 22:35, 26 September 2011 by Michal Harel (Talk | contribs)
(diff) ←Older revision | Current revision (diff) | Newer revision→ (diff)
Jump to: navigation, search


Complexin (CPLX) is the a protein which binds the SNARE protein complex with high affinity. CPLX acts as both inhibitor and facilitator of vescicle fusion and neurotransmitter release at the synapse. CPLX clamps SNARE complexes to prevent vescicle fusion while in another conformation it releases the SNARE complex allowing fusion.

3D structures of complexin

1kil – CPLX + SNARE – rat

3rk3, 3rl0 - CPLX + SNARE – human

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

Retrieved from "http://52.214.119.220/wiki/index.php/Complexin"
Personal tools