Sandbox Reserved 488

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Revision as of 01:46, 26 April 2012 by Thien Tran (Talk | contribs)
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This Sandbox is Reserved from 13/03/2012, through 01/06/2012 for use in the course "Proteins and Molecular Mechanisms" taught by Robert B. Rose at the North Carolina State University, Raleigh, NC USA. This reservation includes Sandbox Reserved 451 through Sandbox Reserved 500.
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c-Myc Protein

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Background

c-Myc protein, also known as Transcription factor p64, is a product of the c-myc proto-oncogene that has the ability to bind to DNA and regulate gene transcription. More specifically, c-Myc recognizes the DNA's core sequence 5'-CAC[GA]TG-3' by forming a heterodimer with MAX, a bHLh protein. This structure then interact with TAF1C, SPAG9,PARP10, KDM5A, and KDM5B. This protein is found mainly in Human and it's known to express the MYC gene using an E.coli expression host.

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