Sandbox Reserved 486
From Proteopedia
This Sandbox is Reserved from 13/03/2012, through 01/06/2012 for use in the course "Proteins and Molecular Mechanisms" taught by Robert B. Rose at the North Carolina State University, Raleigh, NC USA. This reservation includes Sandbox Reserved 451 through Sandbox Reserved 500. |
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More help: Help:Editing For more help, look at this link: http://www.proteopedia.org/wiki/index.php/Help:Getting_Started_in_Proteopedia Diphtheria toxinDiphtheria Toxin is an exotoxin produced by the organism Corynebcterium diphtheria which has been infected by a bacteriophage that contains the Diphtheria toxin gene. It attacks and kills eukaryotic cells by inactivating the Elongation factor (EF-2) in translation. EF-2 allows for translocation of the peptidyl-tRNA from the A-site to the P-site, which in turn frees the A site for another aminoacyl-tRNA to bind. By inactivating the elongation factor during translation the protein being made can not be completed and therefore becomes nonfunctional. Histroy |