This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


Lipase lid morph

From Proteopedia

Revision as of 10:47, 14 May 2012 by Eric Martz (Talk | contribs)
Jump to: navigation, search

Candida rugosa lipase (1trh, 1lpm).

Drag the structure with the mouse to rotate

For an introduction to the structure and function of lipase, please see the article Lipase. This Lipase lid morph article is a supplement to the main article on Lipase.

Candida rugosa lipase (triacylglycerol hydrolase) has been observed in two conformations, with the "lid" closed (1trh) or open (1lpm)[1]. A [2] shows the lid opening and closing.

When open, substrate can access the catalytic triad, Ser209, Glu341, and His449[1]

See Also

Notes and References

  1. ↑ 1.0 1.1 Grochulski P, Li Y, Schrag JD, Cygler M. Two conformational states of Candida rugosa lipase. Protein Sci. 1994 Jan;3(1):82-91. PMID:8142901
  2. ↑ This is a linear interpolation morph. The 14-model PDB file is Image:Morph-linear-1trh-1lpm.pdb.gz.

Proteopedia Page Contributors and Editors (what is this?)

Eric Martz, Karsten Theis

Retrieved from "http://52.214.119.220/wiki/index.php/Lipase_lid_morph"
Personal tools