2fzj

From Proteopedia

proteopedia linkproteopedia link

Template:STRUCTURE 2fzj

Contents 1 New Insights into DHFR Interactions: Analysis of Pneumocystis carinii and Mouse DHFR Complexes with NADPH and Two Highly Potent Trimethoprim Derivatives 2 About this Structure 3 See Also 4 Reference

New Insights into DHFR Interactions: Analysis of Pneumocystis carinii and Mouse DHFR Complexes with NADPH and Two Highly Potent Trimethoprim Derivatives

Template:ABSTRACT PUBMED 17019704

About this Structure

2fzj is a 1 chain structure of Dihydrofolate reductase with sequence from Mus musculus. Full crystallographic information is available from OCA.

See Also

• Dihydrofolate reductase

Reference

• Cody V, Pace J, Chisum K, Rosowsky A. New insights into DHFR interactions: analysis of Pneumocystis carinii and mouse DHFR complexes with NADPH and two highly potent 5-(omega-carboxy(alkyloxy) trimethoprim derivatives reveals conformational correlations with activity and novel parallel ring stacking interactions. Proteins. 2006 Dec 1;65(4):959-69. PMID:17019704 doi:10.1002/prot.21131