2h2q

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Template:STRUCTURE 2h2q

Contents 1 Crystal structure of Trypanosoma cruzi Dihydrofolate Reductase-Thymidylate synthase 2 About this Structure 3 See Also 4 Reference

Crystal structure of Trypanosoma cruzi Dihydrofolate Reductase-Thymidylate synthase

Template:ABSTRACT PUBMED 18536013

About this Structure

2h2q is a 2 chain structure of Dihydrofolate reductase and Thymidylate synthase with sequence from Trypanosoma cruzi. Full crystallographic information is available from OCA.

See Also

• Dihydrofolate reductase
• Thymidylate synthase

Reference

• Schormann N, Senkovich O, Walker K, Wright DL, Anderson AC, Rosowsky A, Ananthan S, Shinkre B, Velu S, Chattopadhyay D. Structure-based approach to pharmacophore identification, in silico screening, and three-dimensional quantitative structure-activity relationship studies for inhibitors of Trypanosoma cruzi dihydrofolate reductase function. Proteins. 2008 Dec;73(4):889-901. PMID:18536013 doi:10.1002/prot.22115