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1vif

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Image:1vif.png

Template:STRUCTURE 1vif

Contents

STRUCTURE OF DIHYDROFOLATE REDUCTASE

Template:ABSTRACT PUBMED 7583655

About this Structure

1vif is a 1 chain structure of Dihydrofolate reductase with sequence from Escherichia coli. Full crystallographic information is available from OCA.

See Also

Reference

  • Narayana N, Matthews DA, Howell EE, Nguyen-huu X. A plasmid-encoded dihydrofolate reductase from trimethoprim-resistant bacteria has a novel D2-symmetric active site. Nat Struct Biol. 1995 Nov;2(11):1018-25. PMID:7583655
  • Strader MB, Chopra S, Jackson M, Smiley RD, Stinnett L, Wu J, Howell EE. Defining the binding site of homotetrameric R67 dihydrofolate reductase and correlating binding enthalpy with catalysis. Biochemistry. 2004 Jun 15;43(23):7403-12. PMID:15182183 doi:10.1021/bi049646k

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