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3k74

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Image:3k74.png

Template:STRUCTURE 3k74

Contents

Disruption of protein dynamics by an allosteric effector antibody

Template:ABSTRACT PUBMED 021238460

About this Structure

3k74 is a 2 chain structure of Dihydrofolate reductase with sequence from Escherichia coli k-12 and Lama glama. Full crystallographic information is available from OCA.

See Also

Reference

  • Oyen D, Srinivasan V, Steyaert J, Barlow JN. Constraining enzyme conformational change by an antibody leads to hyperbolic inhibition. J Mol Biol. 2011 Mar 18;407(1):138-48. Epub 2011 Jan 14. PMID:21238460 doi:10.1016/j.jmb.2011.01.017

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OCA

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