3ql3

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Template:STRUCTURE 3ql3

Contents 1 Re-refined coordinates for PDB entry 1RX2 2 About this Structure 3 See Also 4 Reference

Re-refined coordinates for PDB entry 1RX2

Template:ABSTRACT PUBMED 9012674

About this Structure

3ql3 is a 1 chain structure of Dihydrofolate reductase with sequence from Escherichia coli. Full crystallographic information is available from OCA.

See Also

• Dihydrofolate reductase

Reference

• Sawaya MR, Kraut J. Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence. Biochemistry. 1997 Jan 21;36(3):586-603. PMID:9012674 doi:http://dx.doi.org/10.1021/bi962337c
• Bhabha G, Lee J, Ekiert DC, Gam J, Wilson IA, Dyson HJ, Benkovic SJ, Wright PE. A dynamic knockout reveals that conformational fluctuations influence the chemical step of enzyme catalysis. Science. 2011 Apr 8;332(6026):234-8. PMID:21474759 doi:10.1126/science.1198542