3s7a

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Template:STRUCTURE 3s7a

Contents 1 Human dihydrofolate reductase binary complex with PT684 2 About this Structure 3 See Also 4 Reference

Human dihydrofolate reductase binary complex with PT684

Template:ABSTRACT PUBMED 21931219

About this Structure

3s7a is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Dihydrofolate reductase

Reference

• Cody V, Pace J, Nowak J. Structural analysis of human dihydrofolate reductase as a binary complex with the potent and selective inhibitor 2,4-diamino-6-{2'-O-(3-carboxypropyl)oxydibenz[b,f]-azepin-5-yl}methylpter idine reveals an unusual binding mode. Acta Crystallogr D Biol Crystallogr. 2011 Oct;67(Pt 10):875-80. Epub 2011, Sep 8. PMID:21931219 doi:10.1107/S0907444911030071