1dg8
From Proteopedia
Contents |
DIHYDROFOLATE REDUCTASE OF MYCOBACTERIUM TUBERCULOSIS COMPLEXED WITH NADPH
Template:ABSTRACT PUBMED 10623528
About this Structure
1dg8 is a 1 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.
See Also
Reference
- Li R, Sirawaraporn R, Chitnumsub P, Sirawaraporn W, Wooden J, Athappilly F, Turley S, Hol WG. Three-dimensional structure of M. tuberculosis dihydrofolate reductase reveals opportunities for the design of novel tuberculosis drugs. J Mol Biol. 2000 Jan 14;295(2):307-23. PMID:10623528 doi:http://dx.doi.org/10.1006/jmbi.1999.3328
- Argyrou A, Vetting MW, Aladegbami B, Blanchard JS. Mycobacterium tuberculosis dihydrofolate reductase is a target for isoniazid. Nat Struct Mol Biol. 2006 May;13(5):408-13. Epub 2006 Apr 30. PMID:16648861 doi:10.1038/nsmb1089
Categories: Dihydrofolate reductase | Mycobacterium tuberculosis | Athappilly, F. | Chitnumsub, P. | Hol, W G. | Li, R. | Sirawaraporn, R. | Sirawaraporn, W. | Turley, S. | Wooden, J. | Folateanalog | Nicotinamide adenine dinucleotide | Oxidoreductase | Rossmann fold | Structure-based inhibitor design | Tuberculosis
