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2ano

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Image:2ano.png

Template:STRUCTURE 2ano

Contents

Crystal structure of E.coli dihydrofolate reductase in complex with NADPH and the inhibitor MS-SH08-17

Template:ABSTRACT PUBMED 17125251

About this Structure

2ano is a 1 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA.

See Also

Reference

  • Summerfield RL, Daigle DM, Mayer S, Mallik D, Hughes DW, Jackson SG, Sulek M, Organ MG, Brown ED, Junop MS. A 2.13 A structure of E. coli dihydrofolate reductase bound to a novel competitive inhibitor reveals a new binding surface involving the M20 loop region. J Med Chem. 2006 Nov 30;49(24):6977-86. PMID:17125251 doi:10.1021/jm060570v
  • Pant K, Crane BR. Structure of a loose dimer: an intermediate in nitric oxide synthase assembly. J Mol Biol. 2005 Sep 30;352(4):932-40. PMID:16126221 doi:10.1016/j.jmb.2005.07.070

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OCA

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