3f0x

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Template:STRUCTURE 3f0x

Contents

Staphylococcus aureus F98Y mutant dihydrofolate reductase complexed with NADPH and 2,4-Diamino-5-[3-(3-methoxy-5-(3,5-dimethylphenyl)phenyl)but-1-ynyl]-6-methylpyrimidine

Function

[Q2YY41_STAAB] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).[PIRNR:PIRNR000194]

About this Structure

3f0x is a 1 chain structure with sequence from Staab. Full crystallographic information is available from OCA.

See Also

Proteopedia Page Contributors and Editors (what is this?)

OCA

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