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Amyloid precursor protein
From Proteopedia
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| Human amyloid precursor protein heparin-binding domain 1mwp | |||||||||
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| Resources: | FirstGlance, OCA, RCSB, PDBsum | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
Amyloid precursor protein (APP) is thought to regulate transcription. APP is cleaved by β-secretase and the resulting N terminal peptide which is ca. 40 amino acid long is called hAPP β-peptide. The aggregation of the hAPP β-peptide is the cause of Alzheimer’s Disease. For detailed discussion see
3D structures of amyloid precursor protein
Updated on 17-November-2014
