Dipeptidyl peptidase
From Proteopedia
Dipeptidyl peptidase (DPP) is an enzyme which cleaves dipeptides from polypeptides.
- DPP-I is involved in inflammatory diseases.
- DPP-II is a serine protease.
- DPP-III acts similarly to DPP-IV.
- DPP-IV (or CD26) cleaves proline dipeptides from the N-termini and is associated with immune regulation.
The images at the left and at the right correspond to one representative DPP, i.e. the crystal structure of Dipeptidyl peptidase-I from rat (1jqp). See also Dipeptidyl Peptidase-4 Inhibitor Pharmacokinetics.
3D Structures of Dipeptidyl peptidase
Updated on 24-November-2014
