4m2x, resolution 2.26Å
[DYR_MYCTU] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
OCA
Categories: Dihydrofolate reductase | Jung, H | Sacchettini, J C | Structural genomic | Hydride transfer | Nadph binding | Oxidoreductase-oxidoreductase inhibitor complex | Reductase | Tbsgc