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RNA ligase

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Template:STRUCTURE 1vgj

RNA ligase (LigR) is an enzyme which ligates two ribonucleotide chains using ATP and producing AMP, diphosphate and the ligated ribonucleotide chain[1]. See more details in T4 RNA ligase 2 (Rnl2) and Ligases.


3D Structures of RNA ligase

Updated on 18-August-2016

2hvr, 2hvs – T4LigR 2 + DNA + nucleotide – Enterobacteria phage T4
1s68 - T4LigR 2 N-terminal
2c5u – T4LigR 1 RNA-binding domain
1vgj, 1vdx – LigR – Pyrococcus horikoshii
2vug – LigR – Pyrococcus abyssi
1xdn – LigR 1 editing – Trypanosoma brucei
1iuh – LigR 2’-5’ – Thermus thermophilus
4qak - LigR 2’-5’ – Escherichia coli

References

  1. ↑ Nichols NM, Tabor S, McReynolds LA. RNA ligases. Curr Protoc Mol Biol. 2008 Oct;Chapter 3:Unit3.15. doi:, 10.1002/0471142727.mb0315s84. PMID:18972386 doi:http://dx.doi.org/10.1002/0471142727.mb0315s84

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Michal Harel, Joel L. Sussman, Alexander Berchansky

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