From Proteopedia
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DNA polymerase nu
is the most recently discovered DNA polymerase in the human genome. Although the specific biological functions are unknown, it is known that Pol nu is related to DNA repair and translesion DNA synthesis. It is one of the types of polymerases that is conserved in vertebrates, but it is error-prone, meaning it has low base substitution fidelity. During the replication process in the nucleus, Pol nu discriminates poorly against the misinsertion of dNTP, specifically for guanine again thymine on the . Pol nu interacts with the DNA molecule at the <O helix> of the finger domain on the protein.
