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6FIN, also called DDR1 (Discodein Domain Receptor 1), is a receptor of the collagen.
Function
6 FIN is part of the RTKs family (Receptor Tyrosyne Kinases) which play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene is a RTK that is widely expressed in normal and transformed epithelial cells and is activated by various types of collagen.
6FIN is a transferase, so it is an Enzym which catalyses the transfer reaction of a functional group from a donor molecule to an acceptor one.
Thé inhibition of this protein
Disease
Relevance
Structural highlights
The DDR1 is a protein of 78.1kDa, it is formed of 6 principle α-helix. This protein can bind to 7 ions iodure and a molecule 3-[(3-cyclopropyl-1,2,4-oxadiazol-5-yl)methyl]-8-(1H-indazole-5-carbonyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one.
This is a sample scene created with SAT to by Group, and another to make of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.
