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3D Structures of Actin

Updated on 28-May-2020 {{#tree:id=OrganizedByTopic|openlevels=0|

• α actin 1 (Aa)

• • 3hbt, 2zwh, 1nwk, 1j6z, 3g37, 2y83 – rAa – rabbit
    
  • 2q1n, 2q31, 2a5x, 1rdw, 1rfq, 1lcu – rAa – dimer
    
  • 2hmp – rAa – protease cleaved
    
  • 2zwh, 2gwj, 2gwk – rAa-ATP
    
  • 3b5u – rAa filament – fiber diffraction
    

• α actin 1 complex with gelsolin

• • 2ff3 - rAa+ hGelsolin +domains of hWASP
    
  • 1eqy, 3cjb, 1p8z, 3ffk, 3tu5, 4pkg, 4pkh, 4pki – rAa+hGelsolin
    
  • 1rgi - rAa+hoGelsolin – horse (ho)
    
  • 1t44 - rAa+hGelsolin/mThymosin β-4
    
  • 4z94 - rAa+hGelsolin/tropomodulin/leiomodin
    
  • 2ff6 - rAa+DmCiboulot+hGelsolin
    
  • 1mdu – cAa+hGelsolin - chicken
    
  • 4cbu, 5mvv – PfAa + gelsolin – Plasmodium falciparum
    
  • 4cbw – PbAa + gelsolin – Plasmodium berghei
    

• α actin 1 complex with small molecule

• • 2q36, 1qz5 – rAa+kabiramide C + ATP
    
  • 2vyp – rAa+myxobacterial rhizopodin + ATP
    
  • 1ijj - rAa+latrunculin A
    
  • 2fxu – rAa+bistramide A
    
  • 1wua – rAa+alpyronine A
    
  • 4k41, 1qz6, 1s22, 4k42, 4k43, 2asm, 2asp, 2aso, 1yxq, 1s22, 3m6g, 6mgo - rAa+ macrolide
    
  • 1qz6 – rAa+jaspisamide A
    
  • 6qri – rAa+ chivosazole
    
  • 3mfp, 4a7n, 3jbj, 6bnu, 3j8i, 3j8j, 3j8k, 6bno, 6avb, 6av9, 5mvy, 5mva, 6fhl, 5oof, 5ooe, 5ood, 5ooc, 5onv, 6t23, 6t24, 6vau – rAa + ADP – Cryo EM
    
  • 6kll, 6kln – mAa + ADP – mouse - Cryo EM
    
  • 6djm – cAa + AMPPNP - Cryo EM
    
  • 6djn, 6djo, 7bt7 – cAa + ADP - Cryo EM
    
  • 6iug – Aa + ADP – maize - Cryo EM
    
  • 5ogw – PfAa + jasplakinolide + ADP – Cryo EM
    
  • 6bqw – Aa + AMPPNP – Bacillus subtilis - Cryo EM
    

• α actin 1 complex with protein

• • 6fm2 – hAa + adenylyl cyclase-asociated protein
    
  • 5nol, 5noj, 5nog – Aa + tropomyosin alpha-1 + ADP – pig - Cryo EM
    
  • 3j8a - mAa + tropomyosin - mouse
    
  • 4a7f, 4a7h, 4a7l, 5h53, 5kg8 – rAa + tropomyosin α-1 + myosin heavy chain (mutant) – Cryo EM
    
  • 5jlf, 3j8a – rAa + tropomyosin alpha-1 + ADP – Cryo EM
    
  • 6kn7, 6kn8 – rAa + tropomyosin alpha-1 + Troponin + ADP – Cryo EM
    
  • 6c1h, 6c1g, 6c1d - rAa + myosin + calmodulin
    
  • 6bnv - rAa + myosin + calmodulin – Cryo EM
    
  • 6bnw, 6bnp, 6bih - rAa + myosin – Cryo EM
    
  • 6bnq, 6blh - rAa + myosin + ADP – Cryo EM
    
  • 2v51, 2v52, 2yje, 2yjf – rAa+mMKL/Myocardin-like protein
    
  • 2vcp – rAa+ neural wiskott-aldrich syndrome protein (hWASP) – human (h)
    
  • 2a3z, 2a40, 2a41 – rAa+cDNase I+domains of hWASP – cow (c)
    
  • 2a42 – rAa+cDNase I
    
  • 4eah – rAa + formin-like protein 3 FH2 domain
    
  • 3daw – rAa+mTwinfilin-1
    
  • 6rsw – rAa + mTwinfilin-1 + CAP-1 + ADP
    
  • 3buz – rAa+Iota toxin component IA
    
  • 4b1u, 4b1v, 4b1w, 4b1x, 4b1y, 4b1z – rAa + phosphatase and actin regulator
    
  • 4pl8 - rAa+ Thymosin β-4
    
  • 3u8x - rAa+DmThymosin β-4 - Drosophila melanogaster
    
  • 1esv - rAa+hGelsolin+ latrunculin A
    
  • 3cjc - rAa+hGelsolin+cDNase I
    
  • 2d1k - rAa+hWH2 domain of MIN+cDNase I
    
  • 2pbd, 5zzb, 5zza, 5yee – rAa+hProfilin-1
    
  • 6nas, 6nbe, 6nbw – rAa + hProfilin-1 + acetyltransferase + acetyl CoA + ATP
    
  • 2pav - rAa+hProfilin-1+hVASP
    
  • 2q97 – rAa+toxofilin – Toxoplasma gondii
    
  • 2q0r – rAa+pectenotoxin-2
    
  • 2q0u - rAa+pectenotoxin-2+latrunculin B
    
  • 1y64 – rAa+yBNI1 domain FH2 - yeast
    
  • 1sqk – rAa+DmCiboulot
    
  • 3sjh, 3u9d, 3u9z - rAa+DmCiboulot thymosin β-4 domain
    
  • 3mn5 – rAa+ DmSpire WH2 domain
    
  • 1lot, 1kxp, 1ma9 – rAa+hVitamin D binding protein
    
  • 3m1f – rAa+VOPL WH2 domain
    
  • 3m3n – rAa+mN-WASP
    
  • 3tpq – rAa + MAL RPEL domain
    
  • 3ue5 – rAa + spire domain D
    
  • 4gy2 – rAa + ι toxin component IA
    
  • 3jbi – rAa + vinculin - CryoEM
    
  • 3jbk – rAa + metavinculin + ADP - CryoEM
    
  • 6t1y, 6t20, 6t25, [[6u96] – rAa + phalloidin + ADP - CryoEM
    
  • 4wyb – rAa + BUD6
    
  • 4v0u – rAa + protein phosphatase 1 +serine/threonine protein phosphatase
    
  • 4h0t – rAa + ι toxin component IA + ADPR
    
  • 4h03, 4h0v, 4h0x, 4h0y – rAa + ι toxin component IA + NAD
    
  • 5ypu – rAa + protein cordon-bleu WH2 domain
    
  • 6jbk, 6jcu, 6jh8, 6jh9 – rAa + protein cordon-bleu peptide
    
  • 6gvc – rAa + Rho GTPase-activating protein
    
  • 6uby, 6uc0, 6uc4, 6vao – rAa + cofilin 1 + ADP – Cryo EM
    
  • 2w49 – cAa +troponin C+ troponin T+ troponin I+ tropomyosin α-1
    
  • 3j4k - cAa + tropomyosin
    
  • 7bti - cAa + phalloidin + ADP – Cryo EM
    
  • 6d8c - cAa + filamin + phalloidin – Cryo EM
    
  • 5yu8 – cAa + cofilin 2
    
  • 6m5g - cAa + utrophin + ADP – Cryo EM
    
  • 7bte - cAa + lifeact + ADP – Cryo EM
    
  • 5ce3, 4ci6 – Aa + protein kinase YopO – fall armyworm
    
  • 5i9e – yAa + actin-related protein 4 + helicase
    
  • 6i4d – PfAa + mGelsolin
    
  • 6i4e, 6i4m – PfAa + mGelsolin + ADP
    
  • 6i4i, 6i4j – PfAa (mutant) + mGelsolin + ADP
    
  • 6i4f, 6i4l – PfAa (mutant) + mGelsolin + ATP + ADP
    
  • 6i4g, 6i4h, 6i4k – PfAa (mutant) + mGelsolin + ATP
    

• β actin (Ab)

• • 3lue – hAb+hAlpha-actinin
    
  • 3byh – hAb+hFimbrin ABD2 – Cryo EM
    
  • 3j82 – hAb + DNGR-1 - CryoEM
    
  • 6anu – hAb + spectrin – Cryo EM
    
  • 3u4l, 3ub5 – Ab + profilin-1 - bovine
    
  • 2oan – cAb
    
  • 3j0s – cAb + cofilin 2
    
  • 4cbx – PbAb + gelsolin
    

• γ 1 actin (Ag)

• • 1h1v – hAg+rGelsolin
    
  • 5jlh, 6g2t, 6cxj, 6cxi – hAg + myosin-14 + tropomyosin alpha-3 – Cryo-EM
    
  • 1atn – rAg+cDNase I
    
  • 1hlu, 2btf – cAg+cProfilin
    
  • 1o1g, 1o1a, 1o1b, 1o1c, 1o1d, 1o1e, 1o1f, 1o18, 1o19, 1mvw, 1m8q – cAg+cMyosin II - tomography
    
  • 3w3d – cAg + DNase I
    
  • 3chw – Major DdAg+hProfilin+poly-Pro repeat – Dictyostelium discoideum
    
  • 3ci5, 3cip, 1nmd - Major DdAg+hGelsolin
    
  • 3a5l, 3a5m, 3a5n, 3a5o - Major DdAg+hGelsolin (mutant)
    
  • 1c0g, 1dej – DdAg:tetrahymenatA+hGelsolin
    
  • 1nm1 - DdAg+hGelsolin+Mg-ATP
    
  • 1nlv, 1c0f – DdAg+hGelsolin
    
  • 1yvn – yA (mutant)+hGelsolin
    
  • 1yag - yA+hGelsolin
    
  • 1d4x – Ag 1/3+hGelsolin – C. elegans
    
  • 3b63 – actin filament – Limulus polyphemus
    

• Actin 5C (A5C)

• • 4rwt, 5wfn – DmA5C + leiomodin
    
  • 3eks – DmAg 5c (mutant)
    
  • 3eku – DmAg 5c (mutant)+cytochalasin D
    
  • 3el2, 2hf4 - DmAg 5c (mutant)+Ca-ATP
    
  • 2hf3 - DmAg 5c (mutant)+Ca-ADP
    
  • 3mmv – DmA-5C+spire WH2 domain
    
  • 3mn6, 3mn7, 3mn9 - DmA-5C (mutant)+spire
    
  • 4jhd – DmAg 5c + protein cordon-bleu WH2 domain
    
  • 4efh – A + spire domains C,D – Acanthamoeba castellanii

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