The genome of the SARS-CoV-2 virus codes for 28 proteins:
Out of those, 19 have already been characterized structurally. For the rest there are accurate AlphaFold2 predicted structures.
Details of the 3D structure & function of the key proteins & RNA inside the virus can be seen in the NY Times[1].
"The first viral protein created inside the infected cell, ORF1ab, is actually a chain of 16 proteins joined together. Two of these proteins act like scissors, snipping the links between the different proteins and freeing them to do their jobs."[1]
SARS-CoV-2 Protein Organization, redrawn from NY Times
[1].
Morph of the top 5 ranked
AlphaFold2 models of
SARS-CoV-2 Protein M,
rainbow color coded N-C (blue to red)
[2].
References
- ↑ 1.0 1.1 1.2 NY Times (3-Apr-2020) Bad News Wrapped in Protein: Inside the Coronavirus Genome
- ↑ Cite error: Invalid
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