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Introduction
Thyroid Stimulating Hormone Receptor (TSHR) is a type of G-Protein Coupled Receptor (GPCR) found in human thyroid follicles. It is activated by the Thyroid Stimulating Hormone (TSH) which is known as thyrotropin. Activation of TSHR is neccessary for activating a signaling pathway for the production of thyroid hormones such as T3 and T4
Structure
(no G-protein or TSH)
Transmembrane Region
()
Hinge Region
Leucine Rich Domain
Binding Pocket
Active vs Inactive State
Specific Residues
Biological Relevance
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