G3p

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Contents

Overview

Image:Wt and pIII.jpg
Figure Adapted from Hill and Stockley et al, 1996 [1]

Gene 3 protein (g3p pr pIII) is a minor coat protein found on the surface of filamentous bacteriophage [2]. The protein consists of 406 amino acids divided into three domains interspaced with glycine linkers [2] [3]. Peptides or proteins can be fused to g3p and evaluated for binding or other properties.



Structural Analysis

Information regarding structure of g3p goes here. Template:STRUCTURE 2g3p

Functional Implications

The relationship between domains and infectivity goes here.

Evolutionarily Related Proteins

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References

  1. ↑ Hill HR, Stockley PG. Phage presentation. Mol Microbiol. 1996 May;20(4):685-92. PMID:8793867 doi:10.1111/j.1365-2958.1996.tb02508.x
  2. ↑ 2.0 2.1 Lubkowski J, Hennecke F, Pluckthun A, Wlodawer A. The structural basis of phage display elucidated by the crystal structure of the N-terminal domains of g3p. Nat Struct Biol. 1998 Feb;5(2):140-7. PMID:9461080
  3. ↑ Cabilly S. The basic structure of filamentous phage and its use in the display of combinatorial peptide libraries. Mol Biotechnol. 1999 Sep;12(2):143-8. PMID:10596371 doi:10.1385/MB:12:2:143

Proteopedia Page Contributors and Editors (what is this?)

Leah Novinger, Michal Harel, Alexander Berchansky

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