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Article title matches

  1. Malarial Dihydrofolate Reductase as Drug Target (10,680 bytes)
    2: ...dium parasites stably expressing Plasmodium vivax dihydrofolate reductase-thymidylate synthase as in vitro and in...
    8: <scene name='Malarial_Dihydrofolate_Reductase_as_Drug_Target/Quadruple_mutant/2'>quad...
    9: <scene name='Malarial_Dihydrofolate_Reductase_as_Drug_Target/Point_mutations/1'>point...
    15: ...essed the steric clash that <scene name='Malarial_Dihydrofolate_Reductase_as_Drug_Target/Pyrimethamine_with_wt_pf...
    25: ...en bonds with the conserved <scene name='Malarial_Dihydrofolate_Reductase_as_Drug_Target/Pfdhfr_arg122/1'>Arg122<...
  2. Dihydrofolate reductase (11,122 bytes)
    1: [[Image:34-DihydrofolateReductase-3dfr-1dls.PNG|thumb|350px|E. coli (left)...
    2: ....org/motm/34</ref>. It catalyzes the reduction of dihydrofolate to tetrahydrofolate, with NADPH acting as hydride...
    9: ...action catalyzed by DHFR reduces a double bond in dihydrofolate (DHF) to form tetrahydrofolate (THF) by transferi...
    11: ...action catalyzed by DHFR reduces a double bond in dihydrofolate (DHF) to form tetrahydrofolate (THF) by transferi...
    13: [[Dihydrofolate reductase]] (DHFR, 1.5.1.3 [https://enzyme.expasy...
  3. Category:Dihydrofolate reductase (54 bytes)
    1: List of pages with the keyword Dihydrofolate reductase
  4. Category:Dihydrofolate Reductase (54 bytes)
    1: List of pages with the keyword Dihydrofolate Reductase
  5. Category:Human dihydrofolate reductase inhibitor complex (78 bytes)
    1: List of pages with the keyword Human dihydrofolate reductase inhibitor complex
  6. Category:Pneumocystis carinii dihydrofolate reductase (75 bytes)
    1: ...st of pages with the keyword Pneumocystis carinii dihydrofolate reductase
  7. Category:Dihydrofolate synthase (53 bytes)
    1: List of pages with the keyword Dihydrofolate synthase
  8. Category:Dihydrofolate (44 bytes)
    1: List of pages with the keyword Dihydrofolate
  9. Category:Mouse holo enzyme ternary ligand complex dihydrofolate reductase (95 bytes)
    1: ... keyword Mouse holo enzyme ternary ligand complex dihydrofolate reductase
  10. Category:Dhfr dihydrofolate reductase (59 bytes)
    1: List of pages with the keyword Dhfr dihydrofolate reductase
  11. Category:Active site mutants ligand complex human dihydrofolate reductase (95 bytes)
    1: ... keyword Active site mutants ligand complex human dihydrofolate reductase
  12. Category:Putative dihydrofolate reductase (63 bytes)
    1: List of pages with the keyword Putative dihydrofolate reductase
  13. Category:Mouse dihydrofolate reductase cofactor ligand complex (84 bytes)
    1: List of pages with the keyword Mouse dihydrofolate reductase cofactor ligand complex
  14. Category:Human dihydrofolate reductase packing (68 bytes)
    1: List of pages with the keyword Human dihydrofolate reductase packing
  15. Category:Dihydrofolate binding (52 bytes)
    1: List of pages with the keyword Dihydrofolate binding
  16. Category:Double mutant human dihydrofolate reductase trimethoprim (87 bytes)
    1: ...ist of pages with the keyword Double mutant human dihydrofolate reductase trimethoprim
  17. Dihydrofolate Reductase (36 bytes)
    1: #Redirect[[Dihydrofolate reductase]]
  18. Dihydrofolate reductase/thymidylate synthase (34 bytes)
  19. Dihydrofolate reductase-thymidylate synthase (34 bytes)
  20. Bifunctional dihydrofolate reductase-thymidylate synthase (37 bytes)
    1: #REDIRECT [[Dihydrofolate reductase]]

Page text matches

  1. 2c2t (3,928 bytes)
    2: ==Human Dihydrofolate Reductase Complexed With NADPH and 2,4-Diamino-5-...
    11: ...DHFR are the cause of megaloblastic anemia due to dihydrofolate reductase deficiency (DHFRD) [MIM:[https://omim.o...
    26: *[[Dihydrofolate reductase 3D structures|Dihydrofolate reductase 3D structures]]
  2. 2c2s (3,778 bytes)
    2: ==Human Dihydrofolate Reductase Complexed With NADPH and 2,4-Diamino-5-...
    11: ...DHFR are the cause of megaloblastic anemia due to dihydrofolate reductase deficiency (DHFRD) [MIM:[https://omim.o...
    26: *[[Dihydrofolate reductase 3D structures|Dihydrofolate reductase 3D structures]]
  3. 4hof (4,167 bytes)
    2: ==Candida albicans dihydrofolate reductase complexed with NADPH and 5-[3-(2-methox...
    14: ...tifungal agents that target the essential enzyme, dihydrofolate reductase (DHFR), in both Candida species would b...
    23: *[[Dihydrofolate reductase 3D structures|Dihydrofolate reductase 3D structures]]
  4. 4hog (3,969 bytes)
    2: ==Candida glabrata dihydrofolate reductase complexed with NADPH and 5-[3-(2-methox...
    14: ...tifungal agents that target the essential enzyme, dihydrofolate reductase (DHFR), in both Candida species would b...
    23: *[[Dihydrofolate reductase 3D structures|Dihydrofolate reductase 3D structures]]
  5. 2bmb (5,025 bytes)
    24: ...tail with the 2,4-diaminopyrimidines that inhibit dihydrofolate reductase. A gene encoding the S.cerevisiae HPPK ...
  6. 1bzf (4,974 bytes)
    2: ...ND DYNAMICS OF THE COMPLEX OF LACTOBACILLUS CASEI DIHYDROFOLATE REDUCTASE WITH THE NEW LIPOPHILIC ANTIFOLATE DRUG...
    24: ...n structure of the complex of Lactobacillus casei dihydrofolate reductase and the anticancer drug trimetrexate. T...
    26: ...in solution of the complex of Lactobacillus casei dihydrofolate reductase with the new lipophilic antifolate drug...
    33: *[[Dihydrofolate reductase 3D structures|Dihydrofolate reductase 3D structures]]
  7. 1e26 (5,455 bytes)
    2: ...Potent Dual Inhibitor of Thymidylate Synthase and Dihydrofolate Reductase as an Antitumor Agent.==
    24: ...zyme, NADP+, and recombinant Pneumocystis carinii dihydrofolate reductase (pcDHFR) refined to an average of 2.15 ...
    26: ...in the crystal structures of Pneumocystis carinii dihydrofolate reductase complexes with folate and NADP+.,Cody V...
    33: *[[Dihydrofolate reductase 3D structures|Dihydrofolate reductase 3D structures]]
  8. 1bsp (5,101 bytes)
    11: ...hyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction pr...
  9. 1bsf (4,931 bytes)
    10: ...hyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction pr...
  10. 1daj (3,039 bytes)
    2: ...LEXES OF PNEUMOCYSTIS CARINII AND WILD TYPE HUMAN DIHYDROFOLATE REDUCTASE WITH COENZYME NADPH AND A NOVEL CLASSIC...
    24: *[[Dihydrofolate reductase 3D structures|Dihydrofolate reductase 3D structures]]
  11. 2bla (4,767 bytes)
    2: ==SP21 double mutant P. vivax Dihydrofolate reductase in complex with pyrimethamine==
    24: Pyrimethamine (Pyr) targets dihydrofolate reductase of Plasmodium vivax (PvDHFR) as well as...
    26: Crystal structure of dihydrofolate reductase from Plasmodium vivax: pyrimethamine di...
    33: *[[Dihydrofolate reductase 3D structures|Dihydrofolate reductase 3D structures]]
  12. 2bl9 (4,672 bytes)
    2: ==X-ray crystal structure of Plasmodium vivax dihydrofolate reductase in complex with pyrimethamine and its d...
    24: Pyrimethamine (Pyr) targets dihydrofolate reductase of Plasmodium vivax (PvDHFR) as well as...
    26: Crystal structure of dihydrofolate reductase from Plasmodium vivax: pyrimethamine di...
    33: *[[Dihydrofolate reductase 3D structures|Dihydrofolate reductase 3D structures]]
  13. 2blc (4,766 bytes)
    2: ==SP21 double mutant P. vivax Dihydrofolate reductase in complex with des-chloropyrimethamine...
    24: Pyrimethamine (Pyr) targets dihydrofolate reductase of Plasmodium vivax (PvDHFR) as well as...
    26: Crystal structure of dihydrofolate reductase from Plasmodium vivax: pyrimethamine di...
    33: *[[Dihydrofolate reductase 3D structures|Dihydrofolate reductase 3D structures]]
  14. 2blb (4,788 bytes)
    2: ==X-ray crystal structure of Plasmodium vivax dihydrofolate reductase in complex with pyrimethamine and its d...
    24: Pyrimethamine (Pyr) targets dihydrofolate reductase of Plasmodium vivax (PvDHFR) as well as...
    26: Crystal structure of dihydrofolate reductase from Plasmodium vivax: pyrimethamine di...
    33: *[[Dihydrofolate reductase 3D structures|Dihydrofolate reductase 3D structures]]
  15. 1bkp (4,931 bytes)
    10: ...hyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction pr...
  16. 1bko (4,932 bytes)
    10: ...hyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction pr...
  17. 2cig (4,477 bytes)
    2: ==Dihydrofolate reductase from Mycobacterium tuberculosis inhibit...
    24: ...er of isoniazid-NADP inhibits the M. tuberculosis dihydrofolate reductase (DHFR), an enzyme essential for nucleic...
    26: Mycobacterium tuberculosis dihydrofolate reductase is a target for isoniazid.,Argyrou A, V...
    33: *[[Dihydrofolate reductase 3D structures|Dihydrofolate reductase 3D structures]]
  18. 1vzq (7,030 bytes)
    26: ...en deleted, and an expression vector carrying the dihydrofolate reductase cDNA. Methotrexate-induced gene amplifi...
  19. 1w7k (4,459 bytes)
    24: ..., the addition of L-glutamate to dihydropteroate (dihydrofolate synthetase activity) and the subsequent additions...
    26: ...erichia coli FolC structure reveals an unexpected dihydrofolate binding site providing an attractive target for a...
  20. 1w78 (4,515 bytes)
    24: ..., the addition of L-glutamate to dihydropteroate (dihydrofolate synthetase activity) and the subsequent additions...
    26: ...erichia coli FolC structure reveals an unexpected dihydrofolate binding site providing an attractive target for a...

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