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Article title matches
- Category:Duggin, I G (42 bytes)
1: List of pages with the keyword Duggin, I G - Category:Duggin, I.G (42 bytes)
1: List of pages with the keyword Duggin, I.G - Category:Duggin IG (40 bytes)
1: List of pages with the keyword Duggin IG
Page text matches
- 1f4k (2,053 bytes)
3: ...ion='[[1f4k]], [[Resolution|resolution]] 2.50Å' scene=''>
4: == Structural highlights ==
5: ...https://proteopedia.org/fgij/fg.htm?mol=1F4K FirstGlance]. <br>
7: ...c.uk/pdbsum/1f4k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1f4k ProSAT]</span></td>...
10: ... IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repea... - 1j0r (3,485 bytes)
3: ...ion='[[1j0r]], [[Resolution|resolution]] 2.50Å' scene=''>
4: == Structural highlights ==
5: ...https://proteopedia.org/fgij/fg.htm?mol=1J0R FirstGlance]. <br>
7: ...c.uk/pdbsum/1j0r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1j0r ProSAT]</span></td>...
10: ... IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repea... - 4b46 (1,909 bytes)
2: ==CetZ1 from Haloferax volcanii - GDP bound monomer==
3: ...ion='[[4b46]], [[Resolution|resolution]] 1.90Å' scene=''>
4: == Structural highlights ==
5: ...https://proteopedia.org/fgij/fg.htm?mol=4B46 FirstGlance]. <br>
7: ...cene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr> - Bacterial Replication Termination (16,233 bytes)
1: ...ination/Tus_opening/1' caption='E. coli TER-binding protein complex with DNA and I- ion (purple) (PDB...
2: ...ctivity and performs similar functions in arresting replication [1].
4: [[Image:Bidirectionalrep2.jpg | thumb | left | 500px | Bacterial replication fo...
8: [[Image:Ecoli ter consensus.png | thumb | left | 350px | ''E. coli ter'' consensu...
10: ... the replication fork means that if an inactivating mutation arises within a ''ter'' site, then arres... - RTP and Tus (17,052 bytes)
1: <StructureSection load='' size='450' side='right' scene='RTP_and_Tus/Practice_structure/2' capti...
3: ...''Escherichia coli'') provides an interesting insight into how proteins with vastly different structu...
5: ...eristics of both proteins.<ref>Wake, RG and King, GF (1997) A tale of two terminators: crystal struct...
7: ...in ''B. subtilis'' and ''E. coli'', Taken from Duggin ''et al'' (2008). ]]
12: ...e at that point. While it is possible for these organisms to function without this type of replicatio... - Replication termination in E. coli and B. subtilis (14,307 bytes)
1: <StructureSection load='1ecr' size='450' side='right' scene='' caption=''>
5: ...he separation of the two parent strands whilst daughter strands are synthesised. The life cycle of ba...
7: ...until it is stopped by its own anticlockwise facing ''ter'' element fork trap [3,4]. <br>
9: ...r'' sites and their highly specific cognate binding capabilities.<br><br>
11: [[Image:Replication_fork.jpg|left|300px|thumb]]<br><br> - User:Karen Lee/Sandbox 1 (12,680 bytes)
1: ...igin and proceeds with two replication forks moving in opposite directions. This process must be term...
3: ...r'' sites. This binding provides a physical blockage in the DNA that stops the replication machinery....
5: ...ps the anti-clockwise replication fork. Interestingly, both these proteins bind to DNA in a polar man...
9: ...ture load='1f4k' size='400' frame='true' align='right' caption="An RTP dimer bound to the B-site ''Te...
12: ...dentification of the ‘winged helix’ DNA-binding domain. ''EMBO J.'' '''15(12)''', 3164-3173.</ref... - User:David Jung/BCHM3981 RTP Tus (23,294 bytes)
1: ...lting the fork from the “blocking” direction (Griffiths, Andersen, and Wake, 1998). This is demon...
3: ...The first level of control of replication was thought to occur before initiation. However, it has bee...
5: ...ows ''Ter'' sites within ''Bacillus subtilis'' |Fig 1. Replication termination (''Ter'') sites in ''B...
8: ... terminator complex was modeled, has also been aligned.]]
9: ...rinucleotide sequence (Lewis ''et al.'', 1990) (Fig 2). Each A and B half-site binds a dimer of RTP a... - User:Cameron Ball/Sandbox 1 (10,805 bytes)
1: ... to the circular bacterial genome to block the progression of DNA polymerase in a polar manner. A pro...
2: ...ematic diagram of the ''B.subtilis'' genome showing clockwise and anticlockwise replication forks and...
5: ...tus gene are still viable<ref>King, G.F., Wake, R.G., A tale of two terminators: crystal structures s...
8: ...0px|right|thumb| DNA sequence of a Ter site showing the A-site in Red, the B-site in Blue and the 3 b...
9: ...King, Reorganization of terminator DNA upon binding replication terminator protein: implications for ... - User:Nathan Harris/Tus (11,921 bytes)
1: ...Tus-Ter Complex. Microbiology and Molecular Biology, 69 (3): 501-526.
4: =='''Biological role'''==
5: ...milar biological roles of RTP and Tus they have significantly different structures <ref name = "Kapla...
9: ...posite to the origin of replication. Within each group the ''Ter'' sites have a coordinated polarity...
12: =='''Structure of Tus protein and binding interactions with TerA'''== - User:Meng Han Liu/Sandbox 1 (4,337 bytes)
3: ...333</ref>. Bacteria uses a [http://en.wikipedia.org/wiki/Circular_bacterial_chromosome#Termination ...
8: ...arrows) and their subsequent fork traps (blue and green).]]
12: ...s region even if one of the replication forks managed to precede the innermost ''Ter'' sites.
16: ...arrest of a replication fork. Molecular Microbiology, 2009. 72(2): p. 279-285</ref>.
24: ...ture load='1f4k' size='400' frame='true' align='right' caption='Symmetric complex' scene='Insert opti... - User:Alexei Ilinykh/Sandbox 1 (21,905 bytes)
4: ...are depicted in red and black respectively. An origin of replication (''OriC'') is also shown.]]
6: ...ay be necessary for orderly segregation of the daughter strands <ref>PMID:19019156</ref>.
10: ...he anticlockwise replication fork is delayed during DNA replication, termination occurs at ''TerC'' s...
12: ...elling from the left and are unimpeded from the right. The nucleotides that interact with the Tus pro...
14: [[Image:Ter_consensus_sequence.jpg||||"middle"|500x75px|||]] - User:Meng Han Liu/DNA termination of replication in E. coli & B. subtilis (22,531 bytes)
3: ...1333</ref>. Bacteria use a [http://en.wikipedia.org/wiki/Circular_bacterial_chromosome#Termination ...
8: ... Modified from <ref name="Duggin 2005"> Duggin, I.G. and J.A. Wilce, Termination of replication in ba...
12: ...s region even if one of the replication forks managed to precede the innermost ''Ter'' sites.
16: ...arrest of a replication fork. Molecular Microbiology, 2009. 72(2): p. 279-285</ref>.
18: ===Biological roles of replication fork traps=== - User:David McDonald/Replication Termination Protein (11,367 bytes)
1: ...NA termination sits (Ter sequences) termination region and arrest the action of the replication fork ...
5: [[Image:Replisome.png]]
7: '' '''Diagram of the bacterial replisome''' ''
9: ...me “replication fork” often used when referring to an active replisome.
11: ...eplisome contains a large array of proteins working collectively to copy the DNA. Three major functio... - Image:Replication fork.jpg (2,318 bytes)
2: ...J) are shown, as is the dif site. The two opposed groups of polar Ter sites form the fork trap;
3: ... TerJ are orientated to block only clockwise moving forks, whereas TerA, TerD, TerE, TerI and TerH ar...
4: ...ows indicate that DNA strand compositional skew organizes the chromosome into two
5: segments bisected by the oriC and dif loci (see text)...
6: ... and TerIX are orientated to block clockwise moving forks, whereas TerII, TerVIII, TerIV, TerVII - Image:DBA model.jpg (603 bytes)
1: ...e DBA model for a polar RTP-Ter complex, indicating
5: ...cannot assemble cooperatively on the DNA in forming each
7: specify the structural mechanism giving rise to cooperativity; this could
8: be mediated through direct protein-protein interactions or by mechan...
9: associated with DNA structural changes. - Replication Termination Protein (7,849 bytes)
1: ...symetric RTP dimer bound to the B site in a Ter region (PDB code [[2dpd]])'>
3: ...ram of RTP monomer with secondary structure highlighted.]]
4: ...DnaB helicase and RNA polymerase. Journal of Biological Chemistry, 276:23471-23479</ref>. For more d...
6: *[[Rtp and Tus DNA Binding]]<br />
10: *[[User:David Jung/BCHM3981 RTP Tus]]<br /> - 4b45 (1,867 bytes)
2: ==CetZ2 from Haloferax volcanii - GTPgS bound protofilament==
3: ...ion='[[4b45]], [[Resolution|resolution]] 2.10Å' scene=''>
4: == Structural highlights ==
5: ...https://proteopedia.org/fgij/fg.htm?mol=4B45 FirstGlance]. <br>
7: ...nd=GSP:5-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE'>GSP</scene></td></tr> - Category:Duggin, I G (42 bytes)
1: List of pages with the keyword Duggin, I G - 6wnm (4,210 bytes)
2: ...e of the filamentous phage Pf4 of Pseudomonas aeruginosa PA01==
3: ...ion='[[6wnm]], [[Resolution|resolution]] 2.58Å' scene=''>
4: == Structural highlights ==
5: ...https://proteopedia.org/fgij/fg.htm?mol=6WNM FirstGlance]. <br>
7: ...lass="sblockDat" id="ligandDat"><scene name='pdbligand=U5J:[(2R)-3-{[2-(carboxymethoxy)benzene-1-carb...
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