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Article title matches

  1. Category:Idh1 (35 bytes)
    1: List of pages with the keyword Idh1

Page text matches

  1. 4i3l (2,839 bytes)
    11: ...rot.org/uniprot/IDHC_HUMAN IDHC_HUMAN] Defects in IDH1 are involved in the development of glioma (GLM) [...
  2. 1t09 (5,643 bytes)
    11: ...rot.org/uniprot/IDHC_HUMAN IDHC_HUMAN] Defects in IDH1 are involved in the development of glioma (GLM) [...
  3. 1t0l (5,785 bytes)
    11: ...rot.org/uniprot/IDHC_HUMAN IDHC_HUMAN] Defects in IDH1 are involved in the development of glioma (GLM) [...
  4. 9vdf (266 bytes)
    7: Description: The crystal structure of IDH1
  5. 9b81 (4,057 bytes)
    2: ==Crystal structure of wild type IDH1 bound to compound 4==
    11: ...rot.org/uniprot/IDHC_HUMAN IDHC_HUMAN] Defects in IDH1 are involved in the development of glioma (GLM) [...
    16: ...o propose how compounds binding in the allosteric IDH1 R132H pocket inhibit the production of 2-Hydroxy ...
    18: ...al, biochemical and biophysical studies of mutant IDH1.,McCoy MA, Lu J, Richard Miller F, Soisson SM, La...
  6. 3blv (4,425 bytes)
    11: [https://www.uniprot.org/uniprot/IDH1_YEAST IDH1_YEAST] Performs an essential role in the oxidativ...
    24: ...alytic sites positioned at the interfaces between IDH1 and IDH2 subunits and define pathways of communic...
  7. 3blw (5,116 bytes)
    11: [https://www.uniprot.org/uniprot/IDH1_YEAST IDH1_YEAST] Performs an essential role in the oxidativ...
    24: ...alytic sites positioned at the interfaces between IDH1 and IDH2 subunits and define pathways of communic...
  8. 3blx (4,163 bytes)
    10: [https://www.uniprot.org/uniprot/IDH1_YEAST IDH1_YEAST] Performs an essential role in the oxidativ...
    23: ...alytic sites positioned at the interfaces between IDH1 and IDH2 subunits and define pathways of communic...
  9. 4i3k (2,862 bytes)
    11: ...rot.org/uniprot/IDHC_HUMAN IDHC_HUMAN] Defects in IDH1 are involved in the development of glioma (GLM) [...
  10. 3inm (5,694 bytes)
    11: ...rot.org/uniprot/IDHC_HUMAN IDHC_HUMAN] Defects in IDH1 are involved in the development of glioma (GLM) [...
    26: ...ed levels of 2HG. These data demonstrate that the IDH1 mutations result in production of the onco-metabo...
    28: Cancer-associated IDH1 mutations produce 2-hydroxyglutarate.,Dang L, Whi...
  11. Isocitrate dehydrogenase (7,824 bytes)
    3: ...atase|IDH kinase/phosphatase (IDHK/P)]]. Human '''IDH1''' is cytoplasmic while '''IDH2''' is mitochondri...
    39: Mutations in Isocitrate Dehdryogenase isotypes, IDH1 and IDH2 have recently been discovered in CNS [[c...
  12. 3map (4,891 bytes)
    11: ...rot.org/uniprot/IDHC_HUMAN IDHC_HUMAN] Defects in IDH1 are involved in the development of glioma (GLM) [...
    16: ...he hypothetically oncogenic reduction activity of IDH1 by this mutation.
    18: ...hanisms of "off-on switch" of activities of human IDH1 by tumor-associated mutation R132H.,Yang B, Zhong...
  13. 3mar (4,821 bytes)
    11: ...rot.org/uniprot/IDHC_HUMAN IDHC_HUMAN] Defects in IDH1 are involved in the development of glioma (GLM) [...
    16: ...he hypothetically oncogenic reduction activity of IDH1 by this mutation.
    18: ...hanisms of "off-on switch" of activities of human IDH1 by tumor-associated mutation R132H.,Yang B, Zhong...
  14. 3mas (4,893 bytes)
    11: ...rot.org/uniprot/IDHC_HUMAN IDHC_HUMAN] Defects in IDH1 are involved in the development of glioma (GLM) [...
    16: ...he hypothetically oncogenic reduction activity of IDH1 by this mutation.
    18: ...hanisms of "off-on switch" of activities of human IDH1 by tumor-associated mutation R132H.,Yang B, Zhong...
  15. 8bay (2,882 bytes)
    2: ==Crystal Structure of IDH1 variant R132C S280F in complex with NADPH, Ca2+ a...
    11: ...rot.org/uniprot/IDHC_HUMAN IDHC_HUMAN] Defects in IDH1 are involved in the development of glioma (GLM) [...
  16. 4kzo (4,978 bytes)
    2: ==Crystal Structure Analysis of human IDH1 mutants in complex with NADP+ and Ca2+/alpha-Keto...
    11: ...rot.org/uniprot/IDHC_HUMAN IDHC_HUMAN] Defects in IDH1 are involved in the development of glioma (GLM) [...
    16: ...he sum of these kinetic changes allows the mutant IDH1 enzymes to reductively trap alphaKG directly into...
    18: Mutant IDH1 Enhances the Production of 2-Hydroxyglutarate Due...
  17. 4l03 (2,739 bytes)
    2: ==Crystal Structure Analysis of human IDH1 mutants in complex with NADP+ and Ca2+/alpha-Keto...
    11: ...rot.org/uniprot/IDHC_HUMAN IDHC_HUMAN] Defects in IDH1 are involved in the development of glioma (GLM) [...
  18. 4l04 (2,684 bytes)
    2: ==Crystal Structure Analysis of human IDH1 mutants in complex with NADP+ and Ca2+/alpha-Keto...
    11: ...rot.org/uniprot/IDHC_HUMAN IDHC_HUMAN] Defects in IDH1 are involved in the development of glioma (GLM) [...
  19. 4l06 (2,685 bytes)
    2: ==Crystal Structure Analysis of human IDH1 mutants in complex with NADP+ and Ca2+/alpha-Keto...
    11: ...rot.org/uniprot/IDHC_HUMAN IDHC_HUMAN] Defects in IDH1 are involved in the development of glioma (GLM) [...
  20. 4umx (4,971 bytes)
    2: ==IDH1 R132H in complex with cpd 1==
    11: ...rot.org/uniprot/IDHC_HUMAN IDHC_HUMAN] Defects in IDH1 are involved in the development of glioma (GLM) [...
    16: ...residue can enable selective inhibition of mutant IDH1, and suggest that differences in magnesium bindin...
    18: ... Inhibition of Mutant Isocitrate Dehydrogenase 1 (IDH1) via Disruption of a Metal Binding Network by an ...

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