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- Image:Workbench Ifnar1.pdb (0 bytes)
- Image:Workbench IFNAR1 Morph2.pdb (0 bytes)
- Image:Workbench IFNAR1 Morph3.pdb (0 bytes)
- Image:IFNw IFNAR1 interaction map.png (0 bytes)
- Category:Ifnar1 (37 bytes)
1: List of pages with the keyword Ifnar1
Page text matches
- 8ewy (4,114 bytes)
11: ...ptor IFNAR2. In response to interferon-binding to IFNAR1-IFNAR2 heterodimer, phosphorylates and activates ... - 1n6u (4,361 bytes)
10: .../uniprot/INAR2_HUMAN INAR2_HUMAN] Associates with IFNAR1 to form the type I interferon receptor. Receptor ...
23: ...ted by a single receptor comprising two subunits, IFNAR1 and IFNAR2. The structure of the IFNAR2 IFN bindi... - 1n6v (4,343 bytes)
10: .../uniprot/INAR2_HUMAN INAR2_HUMAN] Associates with IFNAR1 to form the type I interferon receptor. Receptor ...
23: ...ted by a single receptor comprising two subunits, IFNAR1 and IFNAR2. The structure of the IFNAR2 IFN bindi... - 2hym (5,585 bytes)
10: ...uniprot/INAR2_HUMAN INAR2_HUMAN]] Associates with IFNAR1 to form the type I interferon receptor. Receptor ...
23: ...cell surface receptor consisting of two subunits, IFNAR1 and IFNAR2, associating upon binding of interfero... - Sandbox or (971 bytes)
4: ...improved affinity to interferon alpha receptor 1 (IFNAR1). it contains three mutations on the interface of...
5: ...residue 57 is shown only in ifn beta, which binds IFNAR1 in high affinities, the other two residues does n...
6: ... bind to the residues <scene name='Sandbox_or/Yns_ifnar1/6'>S135 and T181</scene>. - Cytokine receptors (23,583 bytes)
25: ...nary/1'>the membrane-proximal sub-domain (SD4) of IFNAR1</scene> was also created. These structures, in co...
32: ...h2/W-1-tyr_70/1'>Tyr70(IFNAR1)</scene> and Phe238(IFNAR1). Substituting these residues by alanine reduces ...
34: ...would lead to electrostatic repulsion with Asp132(IFNAR1).
35: ... and Ser, respectively, confer tighter binding to IFNAR1, but leave the affinity to IFNAR2 essentially una...
41: Both IFNAR1 and IFNAR2, however, undergo significant domain m... - 2lag (3,810 bytes)
10: .../uniprot/INAR2_HUMAN INAR2_HUMAN] Associates with IFNAR1 to form the type I interferon receptor. Receptor ... - User:David Canner/Workbench (2,991 bytes)
5: ...orkbench/Opening/2' caption='Solved Structures of IFNAR1/2/IFN Complexes'>
9: ...ser:David_Canner/Workbench/Opening_sd4_ternary/1'>IFNAR1-SD4</scene> was also created. These structures, i... - 2kz1 (6,473 bytes)
10: ...uniprot/INAR2_HUMAN INAR2_HUMAN]] Associates with IFNAR1 to form the type I interferon receptor. Receptor ...
23: ...d allosteric changes in IFNalpha2 upon binding of IFNAR1-EC to the binary IFNalpha2-IFNAR2-EC complex. - User:David Canner/Workbench2 (7,668 bytes)
4: ...orkbench/Opening/2' caption='Solved Structures of IFNAR1/2-IFN Complexes'>
10: ====IFNAR1-IFN interaction====
11: ... Ser61 to AAA or to YNS confer tighter binding to IFNAR1, but leave the affinity to IFNAR2 essentially una... - User:David Canner/Workbench3 (4,457 bytes)
5: ...orkbench/Opening/2' caption='Solved Structures of IFNAR1/2/IFN Complexes'>
9: ... Conversely, both in IFNAR1 and IFNAR2 undergo major domain movements upon bi...
11: ...d may slow down the rate of ligand association to IFNAR1 directly from solution. The here proposed mechani... - User:Jaime Prilusky/Workbench/GSpub (14,016 bytes)
5: ...orkbench/Opening/2' caption='Solved Structures of IFNAR1/2/IFN Complexes'>
9: ...ser:David_Canner/Workbench/Opening_sd4_ternary/1'>IFNAR1-SD4</scene> was also created. These structures, i...
16: ====IFNAR1-IFN interaction====
17: ... Ser61 to AAA or to YNS confer tighter binding to IFNAR1, but leave the affinity to IFNAR2 essentially una...
26: ... Conversely, both in IFNAR1 and IFNAR2 undergo major domain movements upon bi... - Journal:Cell:1 (11,900 bytes)
1: ...orkbench/Opening/2' caption='Solved Structures of IFNAR1/2/IFN Complexes, [[1dq8]]'>
8: ...nary/1'>the membrane-proximal sub-domain (SD4) of IFNAR1</scene> was also created. These structures, in co...
21: ====IFNAR1-IFN interaction====
22: ...) leads to a total loss of activity. [[Image:IFNw_IFNAR1_interaction_map.png|300px||left|]]
24: ...would lead to electrostatic repulsion with Asp132(IFNAR1). - 3s8w (4,001 bytes)
11: .../uniprot/INAR2_HUMAN INAR2_HUMAN] Associates with IFNAR1 to form the type I interferon receptor. Receptor ...
14: ...rt with a ligand-induced conformational change in IFNAR1, that collectively control signal initiation and ... - 3s98 (3,795 bytes)
2: ==human IFNAR1==
14: ...rt with a ligand-induced conformational change in IFNAR1, that collectively control signal initiation and ... - 3s9d (3,650 bytes)
14: ...rt with a ligand-induced conformational change in IFNAR1, that collectively control signal initiation and ... - 3se3 (3,816 bytes)
14: ...rt with a ligand-induced conformational change in IFNAR1, that collectively control signal initiation and ... - 3se4 (4,020 bytes)
11: .../uniprot/INAR2_HUMAN INAR2_HUMAN] Associates with IFNAR1 to form the type I interferon receptor. Receptor ...
14: ...rt with a ligand-induced conformational change in IFNAR1, that collectively control signal initiation and ... - Category:Ifnar1 (37 bytes)
1: List of pages with the keyword Ifnar1 - Multiple sclerosis (15,466 bytes)
26: ...1, interferon-β has a much stronger affinity for IFNAR1 than interferon-α.<ref name="Interferon Receptor...
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