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Article title matches
- Category:Irak (35 bytes)
1: List of pages with the keyword Irak - IRAK-4 (54 bytes)
- IRAK-2 (54 bytes)
- Category:Irak-m (37 bytes)
1: List of pages with the keyword Irak-m
Page text matches
- 2nru (6,286 bytes)
2: ==Crystal structure of IRAK-4==
11: ...K4D) [MIM:[https://omim.org/entry/607676 607676]. IRAK4 deficiency causes extracellular pyogenic bacteri...
13: ... to polyubiquitinated IRAK1 bringing together the IRAK1-MAP3K7/TAK1-TRAF6 complex and the NEMO-IKKA-IKKB...
26: ...yrosine kinase. Our results provide insights into IRAK-4 function and the design of selective inhibitors...
28: Crystal structures of IRAK-4 kinase in complex with inhibitors: a serine/thr... - 2nry (6,119 bytes)
2: ==Crystal structure of IRAK-4==
11: ...K4D) [MIM:[https://omim.org/entry/607676 607676]. IRAK4 deficiency causes extracellular pyogenic bacteri...
13: ... to polyubiquitinated IRAK1 bringing together the IRAK1-MAP3K7/TAK1-TRAF6 complex and the NEMO-IKKA-IKKB...
26: ...yrosine kinase. Our results provide insights into IRAK-4 function and the design of selective inhibitors...
28: Crystal structures of IRAK-4 kinase in complex with inhibitors: a serine/thr... - 2oib (6,070 bytes)
2: ==Crystal structure of IRAK4 kinase domain apo form==
11: ...K4D) [MIM:[https://omim.org/entry/607676 607676]. IRAK4 deficiency causes extracellular pyogenic bacteri...
13: ... to polyubiquitinated IRAK1 bringing together the IRAK1-MAP3K7/TAK1-TRAF6 complex and the NEMO-IKKA-IKKB...
26: ...yrosine, a unique feature of the IRAK family. The IRAK4 structures also provide insights into the regula... - 2oic (6,147 bytes)
2: ==Crystal structure of IRAK4 kinase domain complexed with staurosporine==
11: ...K4D) [MIM:[https://omim.org/entry/607676 607676]. IRAK4 deficiency causes extracellular pyogenic bacteri...
13: ... to polyubiquitinated IRAK1 bringing together the IRAK1-MAP3K7/TAK1-TRAF6 complex and the NEMO-IKKA-IKKB...
26: ...yrosine, a unique feature of the IRAK family. The IRAK4 structures also provide insights into the regula... - 2oid (6,170 bytes)
2: ==Crystal structure of IRAK4 kinase domain complexed with AMPPNP==
11: ...K4D) [MIM:[https://omim.org/entry/607676 607676]. IRAK4 deficiency causes extracellular pyogenic bacteri...
13: ... to polyubiquitinated IRAK1 bringing together the IRAK1-MAP3K7/TAK1-TRAF6 complex and the NEMO-IKKA-IKKB...
26: ...yrosine, a unique feature of the IRAK family. The IRAK4 structures also provide insights into the regula... - Category:Irak (35 bytes)
1: List of pages with the keyword Irak - 3cgf (4,940 bytes)
2: ==IRAK-4 Inhibitors (Part II)- A structure based assessm...
26: ... using a combination of in silico docking into an IRAK-4 homology model, surrogate crystal structure ana...
28: IRAK-4 inhibitors. Part II: a structure-based assessme... - 3cgo (4,962 bytes)
2: ==IRAK-4 Inhibitors (Part II)- A structure based assessm...
26: ... using a combination of in silico docking into an IRAK-4 homology model, surrogate crystal structure ana...
28: IRAK-4 inhibitors. Part II: a structure-based assessme... - 3ega (3,946 bytes)
11: ...ing IRAK kinases and TRAF6. Mediates IL1B-induced IRAK1 'Lys-63'-linked polyubiquitination and possibly ...
14: ...e interaction of this protein with phosphorylated IRAK1. The Pellino FHA domain is decorated with an unu...
16: ...ain that mediates interaction with phosphorylated IRAK1.,Lin CC, Huoh YS, Schmitz KR, Jensen LE, Ferguso... - 3egb (3,714 bytes)
10: ...ing IRAK kinases and TRAF6. Mediates IL1B-induced IRAK1 'Lys-63'-linked polyubiquitination and possibly ...
13: ...e interaction of this protein with phosphorylated IRAK1. The Pellino FHA domain is decorated with an unu...
15: ...ain that mediates interaction with phosphorylated IRAK1.,Lin CC, Huoh YS, Schmitz KR, Jensen LE, Ferguso... - User:Adam Kral/Sandbox 1 (17,202 bytes)
13: ...terleukin-1 receptor (IL-1R)-associated kinase-1 (IRAK-1). BTK is important even for the congenital immu... - Interleukin-1 receptor-associated kinase (2,316 bytes)
1: ...oad='2a9i' size='340' side='right' caption='Mouse IRAK4 death domain complex with Mn+2 ion , [[2a9i]]' s...
3: '''Interleukin-1 receptor-associated kinase''' (IRAK) is a kinase involved in signaling innate immune ...
6: IRAK4 is involved in early recognition of pathogens an...
9: IRAK4 deficiency is a disorder which causes recurrent ...
14: *IRAK1 - Sandbox Reserved 935 (9,133 bytes)
37: ...ems likely that the last common ancestor of Pelle/IRAK kinases and plant receptor kinases already had bo... - 4rmz (5,353 bytes)
2: ==Crystal Structure of IRAK-4==
10: ...K4D) [MIM:[https://omim.org/entry/607676 607676]. IRAK4 deficiency causes extracellular pyogenic bacteri...
12: ... to polyubiquitinated IRAK1 bringing together the IRAK1-MAP3K7/TAK1-TRAF6 complex and the NEMO-IKKA-IKKB...
15: ...yrosine kinase. Our results provide insights into IRAK-4 function and the design of selective inhibitors...
17: Crystal structures of IRAK-4 kinase in complex with inhibitors: a serine/thr... - TIR domain-containing adapter protein (2,076 bytes)
24: **[[3mop]] – hMyD88 death domain + IRAK-2 + IRAK-4<br /> - 5uke (1,886 bytes)
2: ==NMR structure of monomeric human IRAK-M Death Domain R56D, Y61E mutant==
10: [https://www.uniprot.org/uniprot/IRAK3_HUMAN IRAK3_HUMAN] Disease susceptibility is associated with...
12: ...ither inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex.[UniProtKB:Q... - 5w84 (5,571 bytes)
2: ==CRYSTAL STRUCTURE OF IRAK-4 WITH A 4,6-DIAMINONICOTINAMIDE INHIBITOR (COMPO...
13: ...K4D) [MIM:[http://omim.org/entry/607676 607676]]. IRAK4 deficiency causes extracellular pyogenic bacteri...
15: ... to polyubiquitinated IRAK1 bringing together the IRAK1-MAP3K7/TAK1-TRAF6 complex and the NEMO-IKKA-IKKB...
18: ...y X-ray crystal structures of inhibitors bound to IRAK4. Structure activity relationship (SAR) studies l...
20: ... 4,6-diaminonicotinamides as potent and selective IRAK4 inhibitors.,Bhide RS, Keon A, Weigelt C, Sack JS... - 5w85 (5,600 bytes)
2: ==CRYSTAL STRUCTURE OF IRAK-4 WITH A 4,6-DIAMINONICOTINAMIDE INHIBITOR (COMPO...
13: ...K4D) [MIM:[http://omim.org/entry/607676 607676]]. IRAK4 deficiency causes extracellular pyogenic bacteri...
15: ... to polyubiquitinated IRAK1 bringing together the IRAK1-MAP3K7/TAK1-TRAF6 complex and the NEMO-IKKA-IKKB...
18: ...y X-ray crystal structures of inhibitors bound to IRAK4. Structure activity relationship (SAR) studies l...
20: ... 4,6-diaminonicotinamides as potent and selective IRAK4 inhibitors.,Bhide RS, Keon A, Weigelt C, Sack JS... - Category:Irak-m (37 bytes)
1: List of pages with the keyword Irak-m - 6mom (6,443 bytes)
2: ...human Interleukin-1 receptor associated Kinase 4 (IRAK 4, CID 100300) in complex with compound NCC003714...
11: ...K4D) [MIM:[https://omim.org/entry/607676 607676]. IRAK4 deficiency causes extracellular pyogenic bacteri...
13: ... to polyubiquitinated IRAK1 bringing together the IRAK1-MAP3K7/TAK1-TRAF6 complex and the NEMO-IKKA-IKKB...
16: ...ts FLT3 and IRAK1/4 kinases. The multikinase FLT3-IRAK1/4 inhibitor eliminated adaptively resistant FLT3...
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