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- Image:Neh2.pdb (0 bytes)
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- 2flu (3,777 bytes)
2: ==Crystal Structure of the Kelch-Neh2 Complex==
7: ...Bsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2flu ProSAT]</span></td></tr>
19: ...://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2flu ConSurf].
29: <div class="pdbe-citations 2flu" style="background-color:#fffaf0;... - 3zgc (3,684 bytes)
2: ==crystal structure of the KEAP1-NEH2 complex==
7: ...<td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
8: ...Bsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zgc ProSAT]</span></td></tr>
20: <div class="pdbe-citations 3zgc" style="background-color:#fffaf0;... - 2dyh (4,689 bytes)
7: ...<td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
8: ...Bsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dyh ProSAT], [https://www.topsan.org/Protein...
20: ...://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dyh ConSurf].
24: ...to correctly position the lysines within the Nrf2 Neh2 domain for efficient ubiquitination. Together wit...
30: <div class="pdbe-citations 2dyh" style="background-color:#fffaf0;... - 2z32 (4,613 bytes)
7: ...<td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
8: ...Bsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2z32 ProSAT]</span></td></tr>
20: ...://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2z32 ConSurf].
24: ...ures revealed that the DLG and ETGE motifs of the Neh2 domain of Nrf2 and the ProTalpha peptide bind to ...
30: <div class="pdbe-citations 2z32" style="background-color:#fffaf0;... - Kelch-like protein (1,793 bytes)
1: ...mplex with NRF2 Neh2 peptide (green) and sulfate (PDB code [[1x2r]])' scene='70/706701/Cv/1'>
8: *'''KLHL19 (Keap1)''' interacts with the Neh2 peptide of NRF2.<br />
17: ...e='70/706701/Cv/8'>All interactions of Keap1 with Neh2</scene>. Water molecules shown as red spheres. - Kelch-like protein 3D structures (4,219 bytes)
59: ...[[7k2r]], [[7k2s]] – hKeap1 Kelch domain + NRF2 Neh2 peptide <br />
67: **[[1x2r]] – mKeap1 Kelch domain + NRF2 Neh2 peptide <br /> - 6t7z (3,579 bytes)
7: ...ligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
8: ...Bsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6t7z ProSAT]</span></td></tr>
14: ...d Ac-LDEETGEFL-NH2 spanning residues 76-84 of the Neh2 domain of NRF2 with the aim to replace E78, E79 a...
20: <div class="pdbe-citations 6t7z" style="background-color:#fffaf0;... - User:Mathias Bortoletto Dunker/Sandbox 1 (21,078 bytes)
2: ...e='right' caption='Crystal Structure of the Kelch-Neh2 Complex' scene='89/898348/Flu2/1'>
41: ...lexes (CRLs). Once the lysine residues within the Neh2 domain of Nrf2 are marked, cyclical association a...
72: ...e> (dark blue): allows for <scene name='89/898348/Neh2ultima/1'>binding of NRF2 to Keap1, through to deg...
97: ...<scene name='89/898348/Flu2/1'>bind itself to the Neh2 domain of Nrf2.</scene>
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