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Article title matches

  1. Image:SirT1 docking pose.pdb (0 bytes)
  2. Image:SirT1.pdb (0 bytes)
  3. Category:Sirt1 (36 bytes)
    1: List of pages with the keyword Sirt1

Page text matches

  1. 4i5i (15,193 bytes)
    2: ==Crystal structure of the SIRT1 catalytic domain bound to NAD and an EX527 analog...
    7: ...E-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
    8: ...Bsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4i5i ProSAT]</span></td></tr>
    11: ... SirtT1 75 kDa fragment: catalytically inactive 75SirT1 may be involved in regulation of apoptosis. May b...
    14: ...mation sterically prevents substrate binding. The SIRT1/NAD(+)/35 crystal structure defines a novel mecha...
  2. FirstGlance in Jmol Literature Citations (30,325 bytes)
    169: ...ann TI. Adaptation-driven evolution of sirtuin 1 (SIRT1), a key regulator of metabolism and aging, in mar...
    224: ...">Mattila ''et al.'' 2020 provided a downloadable PDB file with a link to view it by uploading to ''Fir...
    317: ... Jmol'' that will allow the reader to call up the pdb file in a simple Web-based viewer that is browser...
  3. 4if6 (13,110 bytes)
    7: ...SINE-5-DIPHOSPHORIBOSE'>APR</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
    8: ...Bsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4if6 ProSAT]</span></td></tr>
    11: ... SirtT1 75 kDa fragment: catalytically inactive 75SirT1 may be involved in regulation of apoptosis. May b...
  4. 1u8f (3,881 bytes)
    7: ...<td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD<...
    8: ...Bsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1u8f ProSAT]</span></td></tr>
    11: ...-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. Modulates the organization and ...
    20: ...://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1u8f ConSurf].
  5. 1ukh (6,921 bytes)
    7: ...Bsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ukh ProSAT]</span></td></tr>
    10: ...at shock factor protein 4 (HSF4), the deacetylase SIRT1, ELK1, or the E3 ligase ITCH.<ref>PMID:16581800</...
    19: ...://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ukh ConSurf].
    29: <div class="pdbe-citations 1ukh" style="background-color:#fffaf0;...
  6. 1uki (7,115 bytes)
    7: ...<td class="sblockDat" id="ligandDat"><scene name='pdbligand=537:2,6-DIHYDROANTHRA/1,9-CD/PYRAZOL-6-ONE'...
    8: ...Bsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1uki ProSAT]</span></td></tr>
    11: ...at shock factor protein 4 (HSF4), the deacetylase SIRT1, ELK1, or the E3 ligase ITCH.<ref>PMID:16581800</...
    20: ...://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1uki ConSurf].
    30: <div class="pdbe-citations 1uki" style="background-color:#fffaf0;...
  7. 1x4k (2,912 bytes)
    7: ...<td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
    8: ...Bsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1x4k ProSAT], [https://www.topsan.org/Protein...
    11: ...nction by enhancing the interaction of FOXO1 with SIRT1 and FOXO1 deacetylation.<ref>PMID:15692560</ref> ...
    20: ...://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1x4k ConSurf].
  8. 1x4l (2,936 bytes)
    7: ...<td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
    8: ...Bsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1x4l ProSAT], [https://www.topsan.org/Protein...
    11: ...nction by enhancing the interaction of FOXO1 with SIRT1 and FOXO1 deacetylation.<ref>PMID:15692560</ref> ...
    20: ...://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1x4l ConSurf].
  9. 1znq (3,898 bytes)
    7: ...<td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD<...
    8: ...Bsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1znq ProSAT]</span></td></tr>
    11: ...-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. Modulates the organization and ...
    20: ...://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1znq ConSurf].
  10. 1zr5 (4,479 bytes)
    7: ...Bsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zr5 ProSAT]</span></td></tr>
    19: ...://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1zr5 ConSurf].
    23: ...in. Here we show that human macroH2A1.1 binds the SirT1-metabolite O-acetyl-ADP-ribose (OAADPR) through i...
    29: <div class="pdbe-citations 1zr5" style="background-color:#fffaf0;...
  11. 2d8z (2,866 bytes)
    7: ...<td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
    8: ...Bsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d8z ProSAT], [https://www.topsan.org/Protein...
    11: ...nction by enhancing the interaction of FOXO1 with SIRT1 and FOXO1 deacetylation.<ref>PMID:15692560</ref> ...
    20: ...://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2d8z ConSurf].
  12. 2fxk (4,605 bytes)
    5: ...PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1zq0 1zq0]. Full crystallographic inform...
    7: ...Bsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fxk ProSAT]</span></td></tr>
    19: ...://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fxk ConSurf].
    23: ...in. Here we show that human macroH2A1.1 binds the SirT1-metabolite O-acetyl-ADP-ribose (OAADPR) through i...
    29: <div class="pdbe-citations 2fxk" style="background-color:#fffaf0;...
  13. 2g01 (6,076 bytes)
    7: ...O[3,4-B]QUINOLIN-4-ONE'>73Q</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
    8: ...Bsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2g01 ProSAT]</span></td></tr>
    11: ...at shock factor protein 4 (HSF4), the deacetylase SIRT1, ELK1, or the E3 ligase ITCH.<ref>PMID:16581800</...
    20: ...://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2g01 ConSurf].
    30: <div class="pdbe-citations 2g01" style="background-color:#fffaf0;...
  14. 2gmx (6,830 bytes)
    7: ...ETHOXYPHENYL)ACETAMIDE'>877</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
    8: ...Bsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gmx ProSAT]</span></td></tr>
    11: ...at shock factor protein 4 (HSF4), the deacetylase SIRT1, ELK1, or the E3 ligase ITCH.<ref>PMID:16581800</...
    20: ...://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gmx ConSurf].
    30: <div class="pdbe-citations 2gmx" style="background-color:#fffaf0;...
  15. 2h96 (6,339 bytes)
    7: ...pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
    8: ...Bsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2h96 ProSAT]</span></td></tr>
    11: ...at shock factor protein 4 (HSF4), the deacetylase SIRT1, ELK1, or the E3 ligase ITCH.<ref>PMID:16581800</...
    20: ...://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2h96 ConSurf].
    30: <div class="pdbe-citations 2h96" style="background-color:#fffaf0;...
  16. 9l3e (3,414 bytes)
    7: ...4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
    8: ...Bsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9l3e ProSAT]</span></td></tr>
    11: ...-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. Modulates the organization and ...
  17. 2jo8 (6,478 bytes)
    7: ...Bsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jo8 ProSAT]</span></td></tr>
    10: ...pendent manner. Phosphorylates SIRT1 and inhibits SIRT1-mediated p53/TP53 deacetylation, thereby promotin...
    19: ...://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jo8 ConSurf].
    29: <div class="pdbe-citations 2jo8" style="background-color:#fffaf0;...
  18. 2no3 (5,951 bytes)
    7: ...N-4-YL}AMINO)BENZAMIDE'>859</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
    8: ...Bsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2no3 ProSAT]</span></td></tr>
    11: ...at shock factor protein 4 (HSF4), the deacetylase SIRT1, ELK1, or the E3 ligase ITCH.<ref>PMID:16581800</...
    20: ...://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2no3 ConSurf].
    30: <div class="pdbe-citations 2no3" style="background-color:#fffaf0;...
  19. 3gpd (4,457 bytes)
    5: ....doi.org/10.2210/rcsb_pdb/mom_2004_2 10.2210/rcsb_pdb/mom_2004_2]. Full crystallographic information is...
    7: ...E-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
    8: ...Bsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3gpd ProSAT]</span></td></tr>
    11: ...-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. Modulates the organization and ...
    20: ...://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3gpd ConSurf].
  20. 8g12 (4,579 bytes)
    7: ...<td class="sblockDat" id="ligandDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr...
    8: ...Bsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8g12 ProSAT]</span></td></tr>
    11: ...-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. Modulates the organization and ...
    20: <div class="pdbe-citations 8g12" style="background-color:#fffaf0;...

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