Search results

From Proteopedia

There is no page with the exact title "Statin". The search results for "Statin" are displayed below. You can create a page titled Statin (by clicking on the red link).

For more information about searching Proteopedia, see Help.

Showing below up to 20 results starting with #1.

Article title matches

1. Category:Statin (37 bytes)
   1: List of pages with the keyword Statin
2. Statin Pharmacokinetics (1,335 bytes)
   3: ! colspan="7" align="center"| Statin [[Pharmacokinetics]] at 10mg Dosage
   6: ! [[Atorvastatin]] (Lipitor)
   7: ! [[Fluvastatin]] (Lescol)
   8: ! [[Lovastatin]] (Mevacor)
   9: ! [[Simvastatin]] (Zocor)
3. Treatments:Statin Pharmacokinetics References (202 bytes)
   1: References for [[Statin Pharmacokinetics]]<ref>PMID:11907637</ref><ref>PM...
4. Image:Statin mechanism.gif (0 bytes)

Page text matches

1. 4ixt (4,271 bytes)
   14: ...ybutyrate, an important chiral building block for statin synthesis. One of the enzyme variants, HheC2360, ...
2. 1xdd (4,979 bytes)
   24: ...vivo. Moreover, we demonstrate that the novel lovastatin-derived LFA-1 inhibitor LFA878 exhibits potent an...
   26: ...nction-associated antigen-1 (LFA-1) inhibition by statin derivatives: molecular basis determined by x-ray ...
3. 1xdg (5,003 bytes)
   24: ...vivo. Moreover, we demonstrate that the novel lovastatin-derived LFA-1 inhibitor LFA878 exhibits potent an...
   26: ...nction-associated antigen-1 (LFA-1) inhibition by statin derivatives: molecular basis determined by x-ray ...
4. 4ixw (4,224 bytes)
   14: ...ybutyrate, an important chiral building block for statin synthesis. One of the enzyme variants, HheC2360, ...
5. Category:Statin (37 bytes)
   1: List of pages with the keyword Statin
6. 3b70 (4,482 bytes)
   2: ...structure of Aspergillus terreus trans-acting lovastatin polyketide enoyl reductase (LovC) with bound NADP...
   11: ... during the LovB-mediated biosynthesis of the lovastatin nonaketide chain.<ref>PMID:10334994</ref> <ref>PM...
   24: ...ight possible polyketide intermediates during lovastatin biosynthesis. Such trans-acting ERs have been rep...
   26: ...s-acting polyketide enoyl reductase LovC from lovastatin biosynthesis.,Ames BD, Nguyen C, Bruegger J, Smit...
7. 2bl3 (873 bytes)
   3: ...LASMODIUM FALCIPARUM WITH A LIGAND FROM AN ECODED STATIN COMBINATORIAL LIBRARY==
8. 3h42 (6,197 bytes)
   26: ...creasing LDL uptake. A combination of mAb1 with a statin increases LDLR levels in HepG2 cells more than ei...
9. Atorvastatin (4,760 bytes)
   1: ...on load='' size='340' side='right' caption='Atorvastatin, also known as Lipitor ([[1hwk]])' scene='User:Da...
   5: * Drug Class: [[HMGR]] Inhibitor or Statin
   8: ...rtance: It is the best selling drug in the world. Statins are so ubiquitous, doctors have even suggested h...
   12: ...PMID:11349148</ref> These interactions help Atorvastatin outcompete outcompete HMG-CoA, the substrate of H...
   19: {{:Statin Pharmacokinetics}}
10. Pepsin (17,437 bytes)
    56: **[[1pso]] – hPep + pepstatin<br />
    62: **[[2h6t]] - CaPep residues 59-398 + pepstatin<br />
    64: **[[2qzx]] - CaPep residues 77-418 + pepstatin<br />
    67: **[[1wkr]] - Pep + pepstatin – ''Irpex lacteus''<br />
    68: **[[4apr]], [[5apr]], [[6apr]] - RcPep + pepstatin<br />
11. Rosuvastatin (4,617 bytes)
    1: ...on load='' size='340' side='right' caption='Rosuvastatin, also known as Crestor' scene='User:David_Canner/...
    5: * Drug Class: [[HMGR]] Inhibitor or Statin
    8: ...restor are the fastest growing among the statins. Statins are so ubiquitous, doctors have even suggested h...
    12: ...PMID:11349148</ref> These interactions help Rosuvastatin outcompete HMG-CoA, the substrate of HMGR, in bin...
    19: {{:Statin Pharmacokinetics}}
12. 4iy1 (4,166 bytes)
    14: ...ybutyrate, an important chiral building block for statin synthesis. One of the enzyme variants, HheC2360, ...
13. HMG-CoA Reductase (11,205 bytes)
    9: ...ID:1374417</ref> It is the major target of the '''Statins''' the best selling pharmaceutical drugs in the ...
    14: ...lonate Pathway. Note the early stage at which the statins interfere in the pathway]]
    49: ...mparison of Chemical Structure of HMG-CoA and Lovastatin]]
    53: ...www.medicalnewstoday.com/articles/25046.php</ref> Statin development stands as a triumph for rational drug...
    55: ... (Mevacor), [[cerivastatin]] (Baycol) and [[Atorvastatin]] (Lipitor).
14. Sandbox 55 (12,110 bytes)
    6: =Atorvastatin=
    7: ...ous familial hypercholesterolemia<ref>NIH. "Atorvastatin." PubMed Health. National Institutes of Health, 0...
    9: ... Roth, a Phizer employee, first synthesized atorvastatin in 1985. In 2008 Lipitor was the top-selling phar...
    21: ....jpg|right|thumb| Comparison of HMG-CoA and Atorvastatin ]]
    23: When synthesizing a statin, four properties need to be taken into considerat...
15. User:Eran Hodis/Sandbox7 (10,845 bytes)
    3: ...>PMID:1374417</ref> It is the major target of the Statins, a cholesterol lowering drug class and the best ...
    4: ...lonate Pathway. Note the early stage at which the statins interfere in the pathway]]
    36: ...mparison of Chemical Structure of HMG-CoA and Lovastatin]]
    40: ... levels.<ref>PMID:16386050</ref> As a drug class, statins generated over $20 billion dollars in sales in 2...
    42: ...cene name='HMG-CoA_Reductase/Statin_rosu/4'>rosuvastatin (Crestor)</scene> highlight the important residue...
16. User:Sachin Sundar/Sandbox 1 (17,580 bytes)
    1: ... caption='HMG-CoA Reductase Class II bound to Lovastatin' scene='Insert optional scene name here' />
    4: ..., A. A historical perspective on the discovery of statins https://www.ncbi.nlm.nih.gov/pmc/articles/PMC310...
    8: ...id it have any serious negative side effects. Lovastatin received FDA approval in 1986, and has lowered th...
    12: ...-hydroxyacid form. <ref name= "two">Mevacor (Lovastatin). (2014, February). Retrieved March 28, 2017, fro...
    13: ...der to inhibit the biosynthesis pathway.  As Lovastatin binds to the reductase, this lowers the productio...
17. Simvastatin (5,359 bytes)
    1: ...on='Simvastatin, also known as Zocor' scene='Simvastatin/Just_simva/1'>
    5: * Drug Class: [[HMGR]] Inhibitor or Statin
    8: ...lling drug in 2005 before going off patent. Since statins are so ubiquitous, doctors have even suggested h...
    12: ...>PMID:11349148</ref> These interactions help Simvastatin outcompete HMG-CoA, the substrate of HMGR, in bin...
    19: {{:Statin Pharmacokinetics}}
18. Statin Pharmacokinetics (1,335 bytes)
    3: ! colspan="7" align="center"| Statin [[Pharmacokinetics]] at 10mg Dosage
    6: ! [[Atorvastatin]] (Lipitor)
    7: ! [[Fluvastatin]] (Lescol)
    8: ! [[Lovastatin]] (Mevacor)
    9: ! [[Simvastatin]] (Zocor)
19. Fluvastatin (1,961 bytes)
    1: ...n, also known as Lescol' scene='1Fluvastatin/Fluvastatin/2'>
    5: * Drug Class: [[HMGR]] Inhibitor or Statin
    8: ... Importance: Was largely replaced by [[Lipitor]]. Statins are so ubiquitous, doctors have even suggested h...
    12: ...>PMID:11349148</ref> These interactions help Fluvastatin outcompete HMG-CoA, the substrate of HMGR, in bin...
    19: {{:Statin Pharmacokinetics}}
20. Lovastatin (1,434 bytes)
    1: ...tin, also known as Mevacor' scene='Lovastatin/Lovastatin/1'>
    5: * Drug Class: [[HMGR]] Inhibitor or Statin
    8: * Importance: Was the first HMG-CoA Inhibitor. Statins are so ubiquitous, doctors have even suggested h...
    12: ... the committed step in cholesterol synthesis. Lovastatin outcompetes HMG-CoA, the substrate of HMGR, in bi...
    19: {{:Statin Pharmacokinetics}}

View (previous 20) (next 20) (20 | 50 | 100 | 250 | 500)