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This Months Featured Article

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The Ribosome

by Wayne Decatur

On October 7th, 2009 the Nobel Committee announced three structural biologists would share the 2009 Nobel Prize in Chemistry for studies of the the ribosome. The ribosome is the machine in your cells that accurately and efficiently decodes the genetic information stored in your genome and synthesizes the corresponding polypeptide chain one amino acid at a time in the process of translation. Venkatraman Ramakrishnan of the M.R.C. Laboratory of Molecular Biology in Cambridge, England; Thomas A. Steitz of Yale University; and Ada E. Yonath of the Weizmann Institute of Science in Rehovot, Israel share the prize for the first atomic-resolution structures of the two subunits that come together to form an active ribosome. These structures are considered landmarks for the fact they showed clearly the major contributions to decoding and peptide bond synthesis come from RNA and not protein, as well as for the sheer size of the structures determined. These structures represent tour-de-force efforts in understanding fundamental processes in every organism on earth and will have direct impacts on how we fight pathogenic bacteria in the immediate future. Shown are both subunits of the ribosome, as well as that bind in the complex during the process of translation. (more...)

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New Quality Pages

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Crystal Structure of Vascular Endothelial Growth Factor

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Crystal Structure of Vascular Endothelial Growth Factor Receptor

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Crystal Structure of an Antibody

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Crystal Structure of Triose Phosphate Isomerase

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November 2024: How To Find A Structure is a new guide to finding an empirical model for a protein of interest, choosing which empirical structure is best, and getting an AlphaFold-predicted structure when no empirical structures are available.
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A practical guide to teaching with Proteopedia ^[1]
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↑ Castro C, Johnson RJ, Kieffer B, Means JA, Taylor A, Telford J, Thompson LK, Sussman JL, Prilusky J, Theis K. A practical guide to teaching with Proteopedia. Biochem Mol Biol Educ. 2021 Jun 3. doi: 10.1002/bmb.21548. PMID:34080750 doi:http://dx.doi.org/10.1002/bmb.21548

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eLIFE Labs 2016.

The Journal of Structural Biology 2011.

Genome Biology 2008

Proteopedia Page Contributors and Editors (what is this?)

David Canner, Eran Hodis

Retrieved from "http://52.214.119.220/wiki/index.php/User:David_Canner/sandbox_main3"

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