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<div style="font-size:1.5em;border:1px solid #ddd;background-color:yellow;">Server maintenance warning:<br>
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Proteopedia will be down for infrastructure maintenance from Monday, July 23, 2012 10:00am EDT (Eastern Daylight Time USA) till Monday, July 23, 2012 11:30am EDT (Eastern Daylight Time USA)
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<div style="font-size:175%; padding-top:0.5em; padding-left:30.0px;">Welcome to Proteopedia,</div>
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<div style="border:0px; padding:0px; margin=0px; line-height:2.0em; padding-left:30.0px;">The free, collaborative 3D encyclopedia of proteins & other molecules</div>
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<div style="font-size:1.5em;border:1px solid #ddd;background-color:yellow;padding:10px;"><b>READ-ONLY Mode Mar 18-21 2017</b><br>Proteopedia will be in a READ-ONLY mode for Mar 18-21, 2017, in order to move Proteopedia to a better server. While Proteopedia is in READ-ONLY, it will be possible to search and browse the current pages, but creation or editing of pages will be disabled, and it will not be possible to create new userIDs during this period.
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<span style="font-size:2.0em; border:none; margin:0; padding:0.3em; color:#000;">Welcome to Proteopedia</span>
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<span style="top:+0.2em; font-size:1.2em; padding-left:5px;">The free, collaborative 3D-encyclopedia of proteins & other molecules</span>
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<span style="top:+0.2em; font-size:1.2em; padding-right:5px;">'''''ISSN 2310-6301'''''</span>
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<span style="font-size:1.5em; border:none; margin:0; padding:0.3em;font-weight:bold;"> [[Proteopedia:Table of Contents|Table of Contents]] * [[Proteopedia:Structure Index|Structure Index]] * [[Krebs_cycle_overview|Function to Structure]] * [[Proteopedia:About|About]] * [[Proteopedia:Video_Guide|Video Guide]] * [[Help:Contents|Help]]</span>
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<td align="left" width="50%">[[Proteopedia:About|About]] <font color="blue">•</font> [[Help:Editing|Editing]] <font color="blue">•</font> [[Help:Contents|Help]]</td>
 
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<td align="right" width="50%">[[Proteopedia:Video_Guide|Video Guide]] <font color="blue">•</font> [[Proteopedia:Interesting_Pages|Content (Topic Pages)]] <font color="blue">•</font> [[Proteopedia:What%27s_New|What's New]]</td>
 
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<applet load='2q66' size='300' frame='false' scene='Proteopedia:Main_page_develop/2q66_initial/3' />
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<div style="font-size:200%; line-height:2.0em">[[2q66]] - Poly(A) polymerase</div>
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Poly(A) polymerase binds specifically to ATP and adds it the end of a mRNA chain. This structure contains an oligo(A) polynucleotide with 5 nucleotides, an ATP molecule, and a magnesium ion. … In the <scene name='2q66/2q66_summary/1'>3D figure</scene>, the enzyme is shown as a blue backbone, the RNA chain in yellow, the ATP in red, the Mg<sup>++</sup> in green, and ALA154 in magenta. Several mechanisms are used to achieve the specificity for ATP. The Mg<sup>++</sup> is coordinated by <scene name='2q66/2q66_asp/2'>ASP100 and ASP102</scene>, and the Mg<sup>++</sup> coordinates with the phosphates of ATP, positioning the nucleotide in the active site. The adenine base is sandwiched between the <scene name='2q66/2q66_stacking/2'>terminal base of the RNA (in yellow) and VAL234 (in cyan)</scene>. [[2q66|Read more...]]
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<div style="font-size:120%; line-height:2.0em">Find my protein/molecule</div>
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* [[Hemoglobin]] - the protein in your blood responsible for oxygen transport
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* [[HIV-1 protease]] - a protein made by the HIV virus, crucial for infection
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* [[Lac repressor]] - a protein that controls the expression of bacterial enzymes involved in lactose metabolism
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* All [[PDB]] entries (over 54,000) have pages
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* [[2q66]] - yeast poly(a)-polymerase, adds poly-A tails to nascent messenger RNAs
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* [[Hydrogen bonds]]
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* [[Morphs]] - visualizing conformational changes
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<div align="center">Pages are easy to create and edit, and <font color='green'>'''Green links'''</font> are easy to make! </div>
 
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[[Special:RequestAccount|Request an account]].<br/>''(Members of the scientific community, including students and educators.)''
 
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Get started with our narrated [[Proteopedia:Video_Guide|video guide]], then use our [[Help:Editing|editing-help page]] as a reference.
 
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Help us expand an existing page like [[1twc]] or [[Prion proteins]],
 
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Or [[Help:Editing#How_To_Create_A_New_Page|start a new page]] on your favorite molecule or topic.
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! style="padding:2px" | <h2 id="WCPDFU" style="margin:3px; background:#D9FCDA; font-size:1.25em; font-weight:bold; border:1px solid #a3bfb1; text-align:left; color:#000; padding:0.2em 0.4em;">What Can Proteopedia Do For You?</h2>
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We could use pages on [[DNA]], [[Trypsin]], and [[Myoglobin]], among [[Wanted pages|others]].
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! style="padding:2px;" | <h2 id="PN" style="margin:3px; background:#D9FCDA; font-size:1.25em; font-weight:bold; border:1px solid #a3b0bf; text-align:left; color:#000; padding:0.2em 0.4em;">Proteopedia News</h2>
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<div style="font-size:120%; line-height:2.0em">Scientists and Students</div>
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* Understand and communicate protein 3D structure-function relationships
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** Example: [[1wsu|Elongation factor SelB]], the protein responsible for adding the 21<sup>st</sup> amino acid selenocysteine to a growing protein chain in bacteria, featured in the [[Teaching_Scenes%2C_Tutorials%2C_and_Educators%27_Pages#Molecule_of_the_Month_.28MotM.29_Series|Molecule of the Month]] at the PDB.
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* Develop [[Teaching Scenes, Tutorials, and Educators' Pages|tutorials or molecular scenes]] to project during lectures
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* [[Teaching Strategies Using Proteopedia|Assign students to construct pages]] in Proteopedia for [[Student Projects|class projects]] or reports
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''(You may [[Help:Protected Pages|protect your teaching pages from editing]] by others.)''
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* Create [[3btp|supplementary material]] for your journal publications
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* Create pages about your [[Research Groups|research team or institute]], highlighting structures you have researched.
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''(You may [[Help:Protected Pages|protect such pages from editing]] by others, or [[Proteopedia:Workbench|unwanted viewing]] pre-publication.)''
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''Proteopedia - a scientific 'wiki' bridging the rift between 3D structure and function of biomacromolecules'', '''Genome Biology''' 2008, 9:R121 [http://genomebiology.com/2008/9/8/R121 doi:10.1186/gb-2008-9-8-r121]
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Current revision


Proteopedia Page Contributors and Editors (what is this?)

Eran Hodis, Eric Martz, Joel L. Sussman, Jaime Prilusky, David Canner

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