Amino acid oxidase

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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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'''D-amino acid oxidase'''
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===D-amino acid oxidase===
[[1kif]] – pDAO – pig<br />
[[1kif]] – pDAO – pig<br />
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[[3g3e]] - hDAO + hydroxyquinoline<br />
[[3g3e]] - hDAO + hydroxyquinoline<br />
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'''L-amino acid oxidase'''
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===L-amino acid oxidase===
[[2jae]] – RoLAO – ''Rhodococcus opacus''<br />
[[2jae]] – RoLAO – ''Rhodococcus opacus''<br />

Revision as of 10:40, 30 January 2014

Template:STRUCTURE 2jb1 Amino acid oxidase catalyzes the oxidation of amino acids to the keto acid producing ammonia and hydrogen peroxide. These enzymes oxidize D-amino acids (DAO) and L-amino acids (LAO). The LAO oxidation products are 2-oxo acid, ammonia and hydrogen peroxide. LAO is widely found in snake venom. DAOs oxidize neutral and basic D-amino acids. Some DAOs are used in cancer therapy as inducers of oxidative stress and apoptosis. DAO and LAO use FAD as a cofactor.

Contents

3D structures of amino acid oxidase

Updated on 30-January-2014

D-amino acid oxidase

1kif – pDAO – pig
1c0l – RtDAO – Rhodosporidium toruloides
2e48 - hDAO – human

D-amino acid oxidase complex

1dao – pDAO + methyl-oxo-valeric acid
1ddo – pDAO + imino-tryptophan
1an9 – pDAO + aminobenzoate
1ve9 - pDAO + benzoate
1evi – pDAO + dihydro-pyrrolium-carboxylate
1c0k – RtDAO + L-lactate
1c0p – RtDAO + peroxide
1c0i - RtDAO + aminobenzoate
2du8 - hDAO + benzoate
2e4a - hDAO + aminobenzoate
2e49 - hDAO + iminoserine
2e82 - hDAO + imino-DOPA
3cuk, 3w4i, 3w4j, 3w4k, 3znn, 3zno, 3znp, 3znq - hDAO + inhibitor
3g3e - hDAO + hydroxyquinoline

L-amino acid oxidase

2jae – RoLAO – Rhodococcus opacus
4e0v – LAO – Bothrops jararacussu
1reo – HvLAO - Halys viper
3kve – LAO + Zn – Vipera ammodytes

L-amino acid oxidase complex

1f8r – CrLAO + citrate – Calloselasma rhodostoma
1f8s - CrLAO + aminobenzoate
1tdk – HvLAO + L-vinylglycine – Halys viper
1tdn - HvLAO + L-leucine
1tdo - HvLAO + L-phenylalanine
2jb1 - RoLAO + L-alanine
2jb2 - RoLAO + L-phenylalanine
2jb3 - RoLAO + aminobenzoate
2iid - LAO + L-phenylalanine – Calloselasma rhodostoma

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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