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Troponin
From Proteopedia
(Difference between revisions)
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**[[1lxf]], [[1mxl]] - hTnC N-terminal+hTnI fragment<br /> | **[[1lxf]], [[1mxl]] - hTnC N-terminal+hTnI fragment<br /> | ||
**[[2kgb]] – hTnC (mutant) regulatory domain+TnI<br /> | **[[2kgb]] – hTnC (mutant) regulatory domain+TnI<br /> | ||
| - | **[[1sbj]] – cTnC C-terminal+cTnI N-terminal+Mg | + | **[[2mzp]] - hTnC regulatory domain+TnI switch region (mutant) <br /> |
| + | **[[1sbj]] – cTnC C-terminal+cTnI N-terminal+Mg - NMR<br /> | ||
**[[1scv]], [[1fi5]], [[1blq]] - cTnC C-terminal+cTnI N-terminal – NMR<br /> | **[[1scv]], [[1fi5]], [[1blq]] - cTnC C-terminal+cTnI N-terminal – NMR<br /> | ||
**[[1npq]] - cTnC (mutant) N-terminal+cTnI fragment+rhodamine<br /> | **[[1npq]] - cTnC (mutant) N-terminal+cTnI fragment+rhodamine<br /> | ||
Revision as of 06:57, 22 June 2015
Troponin (Tn) is a regulatory protein in muscle contraction. It contains 3 subunits:
- TnC causes conformational change in TnI when it binds to calcium ions. For more details on TnC see Role of Troponin C in decreased muscle sensitivity to calcium.
- TnT binds to tropomyosin.
- TnI binds to actin which is found in thin muscle filaments.
See additional details in Human Cardiac Troponin C.
3D Structures of Troponin
Updated on 22-June-2015
