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Troponin
From Proteopedia
(Difference between revisions)
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* Troponin C+Troponin I+Troponin T | * Troponin C+Troponin I+Troponin T | ||
| + | **[[1j1d]], [[1j1e]], [[4y99]] – hTnC (mutant)+hTnI (mutant) fragment+hTnT fragment+Ca - human<br /> | ||
**[[2w49]], [[2w4u]] – cTnC+cTnI+cTnT+tropomyosin+actin – chicken<br /> | **[[2w49]], [[2w4u]] – cTnC+cTnI+cTnT+tropomyosin+actin – chicken<br /> | ||
**[[1ytz]] - cTnC+cTnI+cTnT+Ca<br /> | **[[1ytz]] - cTnC+cTnI+cTnT+Ca<br /> | ||
**[[1yv0]] - cTnC+cTnI+cTnT<br /> | **[[1yv0]] - cTnC+cTnI+cTnT<br /> | ||
| - | **[[1j1d]], [[1j1e]], [[4y99]] – hTnC (mutant)+hTnI (mutant) fragment+hTnT fragment+Ca - human | ||
* Troponin C+Troponin I | * Troponin C+Troponin I | ||
| Line 33: | Line 33: | ||
**[[2kgb]] – hTnC (mutant) regulatory domain+TnI - NMR<br /> | **[[2kgb]] – hTnC (mutant) regulatory domain+TnI - NMR<br /> | ||
**[[2mzp]] - hTnC regulatory domain+TnI switch region (mutant) - NMR<br /> | **[[2mzp]] - hTnC regulatory domain+TnI switch region (mutant) - NMR<br /> | ||
| + | **[[1a2x]] - rTnC +rTnI fragment – rabbit<br /> | ||
**[[1sbj]] – cTnC C-terminal+cTnI N-terminal+Mg - NMR<br /> | **[[1sbj]] – cTnC C-terminal+cTnI N-terminal+Mg - NMR<br /> | ||
**[[1scv]], [[1fi5]], [[1blq]] - cTnC C-terminal+cTnI N-terminal – NMR<br /> | **[[1scv]], [[1fi5]], [[1blq]] - cTnC C-terminal+cTnI N-terminal – NMR<br /> | ||
**[[1npq]] - cTnC (mutant) N-terminal+cTnI fragment+rhodamine<br /> | **[[1npq]] - cTnC (mutant) N-terminal+cTnI fragment+rhodamine<br /> | ||
**[[1jc2]] - cTnC C-terminal+cTnI N-terminal<br /> | **[[1jc2]] - cTnC C-terminal+cTnI N-terminal<br /> | ||
| - | **[[1a2x]] - rTnC +rTnI fragment – rabbit<br /> | ||
**[[3tz1]] - TnC C terminal +TnI fragment – akazara scallop<br /> | **[[3tz1]] - TnC C terminal +TnI fragment – akazara scallop<br /> | ||
| Line 56: | Line 56: | ||
**[[1ih0]] - hTnC C-terminal+EMD 57033 – NMR<br /> | **[[1ih0]] - hTnC C-terminal+EMD 57033 – NMR<br /> | ||
**[[2l98]] – hTnC EF-hand domains 3,4 + resveratrol<br /> | **[[2l98]] – hTnC EF-hand domains 3,4 + resveratrol<br /> | ||
| + | **[[1tcf]] – rTnC+Ca<br /> | ||
| + | **[[1tn4]], [[2tn4]] – rTnC (mutant)+Ca<br /> | ||
**[[1la0]], [[4tnc]] – cTnC+Ca<br /> | **[[1la0]], [[4tnc]] – cTnC+Ca<br /> | ||
**[[1dtl]] – cTnC (mutant)+Ca +bepridil<br /> | **[[1dtl]] – cTnC (mutant)+Ca +bepridil<br /> | ||
| Line 73: | Line 75: | ||
**[[2jnf]] – TnC – fly – NMR<br /> | **[[2jnf]] – TnC – fly – NMR<br /> | ||
**[[1r2u]], [[1r6p]] - TnC N-terminal – trout – NMR<br /> | **[[1r2u]], [[1r6p]] - TnC N-terminal – trout – NMR<br /> | ||
| - | **[[1tcf]] – rTnC+Ca<br /> | ||
| - | **[[1tn4]], [[2tn4]] – rTnC (mutant)+Ca | ||
* Troponin I | * Troponin I | ||
Revision as of 10:47, 10 March 2020
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3D Structures of Troponin
Updated on 10-March-2020
References
- ↑ Li MX, Hwang PM. Structure and function of cardiac troponin C (TNNC1): Implications for heart failure, cardiomyopathies, and troponin modulating drugs. Gene. 2015 Oct 25;571(2):153-66. doi: 10.1016/j.gene.2015.07.074. Epub 2015 Jul, 29. PMID:26232335 doi:http://dx.doi.org/10.1016/j.gene.2015.07.074
- ↑ Kimura A, Harada H, Park JE, Nishi H, Satoh M, Takahashi M, Hiroi S, Sasaoka T, Ohbuchi N, Nakamura T, Koyanagi T, Hwang TH, Choo JA, Chung KS, Hasegawa A, Nagai R, Okazaki O, Nakamura H, Matsuzaki M, Sakamoto T, Toshima H, Koga Y, Imaizumi T, Sasazuki T. Mutations in the cardiac troponin I gene associated with hypertrophic cardiomyopathy. Nat Genet. 1997 Aug;16(4):379-82. PMID:9241277 doi:10.1038/ng0897-379
- ↑ Palm T, Graboski S, Hitchcock-DeGregori SE, Greenfield NJ. Disease-causing mutations in cardiac troponin T: identification of a critical tropomyosin-binding region. Biophys J. 2001 Nov;81(5):2827-37. PMID:11606294 doi:http://dx.doi.org/10.1016/S0006-3495(01)75924-3
