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Troponin

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{{STRUCTURE_1yv0| PDB=1yv0 | SIZE=400| SCENE=Troponin/Cv/1 |right|CAPTION=Chicken troponin: subunit T (dark green), subunit I (wheat), subunit C (pink) complex with Mg+2 ion (green) [[1yv0]] }}
{{STRUCTURE_1yv0| PDB=1yv0 | SIZE=400| SCENE=Troponin/Cv/1 |right|CAPTION=Chicken troponin: subunit T (dark green), subunit I (wheat), subunit C (pink) complex with Mg+2 ion (green) [[1yv0]] }}
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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{{#tree:id=OrganizedByTopic|openlevels=0|
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=== Troponin C+Troponin I+Troponin T ===
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* Troponin C+Troponin I+Troponin T
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+
-
[[2w49]], [[2w4u]] – cTnC+cTnI+cTnT+tropomyosin+actin – chicken<br />
+
-
[[1ytz]] - cTnC+cTnI+cTnT+Ca++<br />
+
-
[[1yv0]] - cTnC+cTnI+cTnT<br />
+
-
[[1j1d]], [[1j1e]] – hTnC (mutant)+hTnI (mutant) fragment+hTnT fragment+Ca++ - human
+
-
=== Troponin C+Troponin I ===
+
**[[2w49]], [[2w4u]] – cTnC+cTnI+cTnT+tropomyosin+actin – chicken<br />
 +
**[[1ytz]] - cTnC+cTnI+cTnT+Ca<br />
 +
**[[1yv0]] - cTnC+cTnI+cTnT<br />
 +
**[[1j1d]], [[1j1e]] – hTnC (mutant)+hTnI (mutant) fragment+hTnT fragment+Ca - human
-
[[2krd]], [[2mkp]] – hTnC+hTnI – NMR<br />
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* Troponin C+Troponin I
-
[[1ozs]] - hTnC C-terminal+hTnI N-terminal – NMR<br />
+
-
[[2l1r]] - hTnC C-terminal+hTnI switch region - NMR<br />
+
-
[[1lxf]], [[1mxl]] - hTnC N-terminal+hTnI fragment<br />
+
-
[[2kgb]] – hTnC (mutant) regulatory domain+TnI<br />
+
-
[[1sbj]] – cTnC C-terminal+cTnI N-terminal+Mg++ - NMR<br />
+
-
[[1scv]], [[1fi5]], [[1blq]] - cTnC C-terminal+cTnI N-terminal – NMR<br />
+
-
[[1npq]] - cTnC (mutant) N-terminal+cTnI fragment+rhodamine<br />
+
-
[[1jc2]] - cTnC C-terminal+cTnI N-terminal<br />
+
-
[[1a2x]] - rTnC +rTnI fragment – rabbit<br />
+
-
[[3tz1]] - TnC C terminal +TnI fragment – akazara scallop<br />
+
-
=== Troponin C ===
+
**[[2krd]], [[2mkp]] – hTnC+hTnI – NMR<br />
 +
**[[1ozs]] - hTnC C-terminal+hTnI N-terminal – NMR<br />
 +
**[[2l1r]] - hTnC C-terminal+hTnI switch region - NMR<br />
 +
**[[1lxf]], [[1mxl]] - hTnC N-terminal+hTnI fragment<br />
 +
**[[2kgb]] – hTnC (mutant) regulatory domain+TnI<br />
 +
**[[1sbj]] – cTnC C-terminal+cTnI N-terminal+Mg++ - NMR<br />
 +
**[[1scv]], [[1fi5]], [[1blq]] - cTnC C-terminal+cTnI N-terminal – NMR<br />
 +
**[[1npq]] - cTnC (mutant) N-terminal+cTnI fragment+rhodamine<br />
 +
**[[1jc2]] - cTnC C-terminal+cTnI N-terminal<br />
 +
**[[1a2x]] - rTnC +rTnI fragment – rabbit<br />
 +
**[[3tz1]] - TnC C terminal +TnI fragment – akazara scallop<br />
-
[[2kdh]] – hTnC+green tea polyphenol – NMR<br />
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* Troponin C
-
[[2kfx]] – hTnC (mutant) N-terminal+Ca+naphthalene derivative<br />
+
-
[[2jt0]], [[2jtz]], [[2jt8]], [[2jt3]] – hTnC (mutant) – NMR<br />
+
-
[[2jxl]] - hTnC (mutant) N-terminal – NMR<br />
+
-
[[3rv5]], [[3sd6]], [[3swb]] - hTnC N-terminal<br />
+
-
[[4gjg]] - hTnC N-terminal (mutant)<br />
+
-
[[4gjf]] - hTnC N-terminal (mutant) + Cd<br />
+
-
[[4gje]] - hTnC N-terminal + Cd<br />
+
-
[[1wrk]], [[1wrl]] - hTnC (mutant) N-terminal+trifluoperazine<br />
+
-
[[1spy]] - hTnC N-terminal – NMR<br />
+
-
[[2mle]] - hTnC C-terminal – NMR<br />
+
-
[[2mlf]] - hTnC C-terminal (mutant) – NMR<br />
+
-
[[1ih0]] - hTnC C-terminal+EMD 57033 – NMR<br />
+
-
[[1ap4]] - hTnC N-terminal+Ca++ – NMR<br />
+
-
[[2l98]] – hTnC EF-hand domains 3,4 + resveratrol<br />
+
-
[[1la0]], [[4tnc]] – cTnC+Ca++<br />
+
-
[[1dtl]] – cTnC (mutant)+Ca++ +bepridil<br />
+
-
[[1skt]], [[1zac]], [[2ctn]] - cTnC N-terminal – NMR<br />
+
-
[[1aj4]] - cTnC (mutant) +Ca++ – NMR<br />
+
-
[[3ctn]] - cTnC C-terminal – NMR<br />
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[[1avs]] - cTnC N-terminal+Ca++<br />
+
-
[[1smg]], [[1tnq]] - cTnC N-terminal+Ca++ - NMR<br />
+
-
[[1ncy]] – cTnC+Mn++<br />
+
-
[[1ncx]], [[1ncz]], [[1top]] – cTnC<br />
+
-
[[1pon]], [[1cta]], [[1ctd]] – cTnC fragment – NMR<br />
+
-
[[1tnp]] - cTnC N-terminal – NMR<br />
+
-
[[1tnw]], [[1tnx]] - cTnC +Ca++ - NMR<br />
+
-
[[1trf]] - tTnC N-terminal+Ca++ - turkey – NMR<br />
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-
[[5tnc]] - tTnC<br />
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-
[[2k2a]] - TnC C-terminal – ''Lethocerus indicus'' – NMR<br />
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-
[[2jnf]] – TnC – fly – NMR<br />
+
-
[[1r2u]], [[1r6p]] - TnC N-terminal – trout – NMR<br />
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[[1tcf]] – rTnC+Ca++<br />
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[[1tn4]], [[2tn4]] – rTnC (mutant)+Ca++
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=== Troponin I ===
+
**[[2kdh]] – hTnC+green tea polyphenol – NMR<br />
 +
**[[2kfx]] – hTnC (mutant) N-terminal+Ca+naphthalene derivative<br />
 +
**[[2jt0]], [[2jtz]], [[2jt8]], [[2jt3]] – hTnC (mutant) – NMR<br />
 +
**[[2jxl]] - hTnC (mutant) N-terminal – NMR<br />
 +
**[[3rv5]], [[3sd6]], [[3swb]] - hTnC N-terminal<br />
 +
**[[4gjg]] - hTnC N-terminal (mutant)<br />
 +
**[[4gjf]] - hTnC N-terminal (mutant) + Cd<br />
 +
**[[4gje]] - hTnC N-terminal + Cd<br />
 +
**[[1wrk]], [[1wrl]] - hTnC (mutant) N-terminal+trifluoperazine<br />
 +
**[[1spy]] - hTnC N-terminal – NMR<br />
 +
**[[2mle]] - hTnC C-terminal – NMR<br />
 +
**[[2mlf]] - hTnC C-terminal (mutant) – NMR<br />
 +
**[[1ih0]] - hTnC C-terminal+EMD 57033 – NMR<br />
 +
**[[1ap4]] - hTnC N-terminal+Ca – NMR<br />
 +
**[[2l98]] – hTnC EF-hand domains 3,4 + resveratrol<br />
 +
**[[1la0]], [[4tnc]] – cTnC+Ca<br />
 +
**[[1dtl]] – cTnC (mutant)+Ca +bepridil<br />
 +
**[[1skt]], [[1zac]], [[2ctn]] - cTnC N-terminal – NMR<br />
 +
**[[1aj4]] - cTnC (mutant) +Ca – NMR<br />
 +
**[[3ctn]] - cTnC C-terminal – NMR<br />
 +
**[[1avs]] - cTnC N-terminal+Ca<br />
 +
**[[1smg]], [[1tnq]] - cTnC N-terminal+Ca - NMR<br />
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**[[1ncy]] – cTnC+Mn<br />
 +
**[[1ncx]], [[1ncz]], [[1top]] – cTnC<br />
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**[[1pon]], [[1cta]], [[1ctd]] – cTnC fragment – NMR<br />
 +
**[[1tnp]] - cTnC N-terminal – NMR<br />
 +
**[[1tnw]], [[1tnx]] - cTnC +Ca - NMR<br />
 +
**[[1trf]] - tTnC N-terminal+Ca - turkey – NMR<br />
 +
**[[5tnc]] - tTnC<br />
 +
**[[2k2a]] - TnC C-terminal – ''Lethocerus indicus'' – NMR<br />
 +
**[[2jnf]] – TnC – fly – NMR<br />
 +
**[[1r2u]], [[1r6p]] - TnC N-terminal – trout – NMR<br />
 +
**[[1tcf]] – rTnC+Ca<br />
 +
**[[1tn4]], [[2tn4]] – rTnC (mutant)+Ca
-
[[2jpw]] – TnI biphosphorylated – mouse – NMR<br />
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* Troponin I
-
[[1vdi]] – cTnI – NMR<br />
+
-
[[1vdj]] – cTnI+Ca++ - NMR
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=== Troponin T ===
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**[[2jpw]] – TnI biphosphorylated – mouse – NMR<br />
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**[[1vdi]] – cTnI – NMR<br />
 +
**[[1vdj]] – cTnI+Ca - NMR
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[[2z5h]] – yTnT fragment+tropomyosin – yeast
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* Troponin T
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**[[2z5h]] – yTnT fragment+tropomyosin – yeast
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}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 12:03, 15 December 2014

Template:STRUCTURE 1yv0

Troponin (Tn) is a regulatory protein in muscle contraction. It contains 3 subunits:

See additional details in Human Cardiac Troponin C.

3D Structures of Troponin

Updated on 15-December-2014

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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