Citric Acid Cycle

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*[[Krebs cycle overview]]
*[[Krebs cycle overview]]
*[[Krebs cycle reactions]]
*[[Krebs cycle reactions]]
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The [[Citric Acid Cycle]] (tricarboxylic acid cycle) is a series of enzyme catalyzed reactions which are critical in cellular respiration. Under oxidative conditions, pyruvate continues to be metabolized through the tricarboxylic acid cycle. In this cycle, Acetyl-CoA, a byproduct of [[glycolysis]], along with various cofactors, are broken down into carbon dioxide, water, and energy in the form of GTP and NADH. <span class="bg-pink ">pinl uuuu</span>
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The [[Citric Acid Cycle]] (tricarboxylic acid cycle) is a series of enzyme catalyzed reactions which are critical in cellular respiration. Under oxidative conditions, pyruvate continues to be metabolized through the tricarboxylic acid cycle. In this cycle, Acetyl-CoA, a byproduct of [[glycolysis]], along with various cofactors, are broken down into carbon dioxide, water, and energy in the form of GTP and NADH.
'''Pyruvate decarboxylation or pyruvate oxidation''', also known as the link reaction (or oxidative decarboxylation of pyruvate), is the conversion of pyruvate into Acetyl-CoA by the enzyme complex pyruvate dehydrogenase complex (see [[Pyruvate dehydrogenase]]).
'''Pyruvate decarboxylation or pyruvate oxidation''', also known as the link reaction (or oxidative decarboxylation of pyruvate), is the conversion of pyruvate into Acetyl-CoA by the enzyme complex pyruvate dehydrogenase complex (see [[Pyruvate dehydrogenase]]).

Revision as of 11:49, 15 September 2022

Open conformation of citrate synthase dimer complex with citrate (PDB code 1cts) and closed conformation of citrate synthase dimer complex with citrate and CoA (PDB code 2cts)

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Alexander Berchansky, David Canner, Ann Taylor, Wayne Decatur, Jaime Prilusky

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