Featured Article
|
Green links change the 3D image!
Click and drag on the molecule!
|
|
|
|
|
|
Green fluorescent protein (GFP) is a bioluminescent polypeptide consisting of 238 residues isolated from the body of Aequorea victoria jellyfish.[1] GFP converts the blue chemiluminescent of aequorin in the jellyfish into green fluorescent light.[2] It remains unclear why these jellyfish use fluorescence, why green is better than blue, or why they produce a separate protein for green fluorescence as opposed to simply mutating the present aequorin to shift its wavelength,[3] but in the laboratory, GFP can be incorporated into a variety of biological systems in order to function as a marker protein. Since its discovery in 1962, GFP has become a significant contributor to the research of monitoring gene expression, localization, mobility, traffic, interactions between various membrane and cytoplasmic proteins, as well as many others. (more...)
|
Browse Proteopedia
|
|
Find Your Protein or Biomolecule
|
|
- All PDB entries (over 100,000) have pages
- Go takes you directly to the page if it exists,
- Search gives you search results
|
|
|
What Can Proteopedia Do For You?
|
|
|
|
|
Proteopedia News
|
- October 2025: The Nobel Prize in Chemistry recognizes the development of Metal-Organic Frameworks that have a multitude of potential applications. These are similar to Metal-Ligand Polyhedra, but they form extended crystalline networks instead of discrete polyhedra.
- November 2024: How To Find A Structure is a new guide to finding an empirical model for a protein of interest, choosing which empirical structure is best, and getting an AlphaFold-predicted structure when no empirical structures are available.
- November 2024: How to predict structures with AlphaFold has been updated with instructions for the latest AlphaFold3 Server.
- November 2024: A handful of case studies illustrate what Nobel-Prize winning AlphaFold3 can, and cannot, predict.
- November 2024: There is a new guide to being aware of, and dealing with missing residues and incomplete sidechains.
- March 2024: Professors are using Proteopedia for class projects in Brazil, Czech Republic, France, and various states in the USA. See the updated Adoptions in College and University Classes.
- What happens if a SARS-CoV-2 coronavirus enters your lung? See a clear explanation at Lifecycle of SARS-CoV-2
- July 2022: Exercise-induced N-lactoyl-phenylalanine, appetite and obesity
- 5,000 users!! On December 4, 2021, the number of Proteopedia users went over 5,000. The 5,000th user is from Juniata College, Huntingdon, Pennsylvania, US
- AlphaFold protein structure predictions - a step change for biology, an electronic talk by EBI staff for students and early career researchers via FEBS Junior Sections, Oct. 26, 2021, 19:00 CEST. Announcement. Registration.
- A practical guide to teaching with Proteopedia [4]
How to display cavities, pockets, and tunnels. |
- January 2021: How to display cavities, pockets, and tunnels? Jmol/Cavities_pockets_and_tunnels
- December 2020: What is changing on SARS-CoV-2 virus and what this means for humanity? SARS-CoV-2 spike protein mutations.
- August 2020: An animation of coronavirus spike protein showing the SARS-CoV-2 spike protein fusion transformation.
- July 2020: An animation of coronavirus spike protein showing SARS-CoV-2 protein S priming by furin.
- March 2020: New Proteopedia page focused on the Coronavirus 2019 (COVID-19).
- January 2019: New morphing feature for Proteopedia, powered by PyMOL from from Schrodinger.
- January, 2018: 10th Anniversary Celebration Conference, University of Massachusetts, Amherst, USA. Group Photo of Participants.
- September, 2017: A workshop based on Proteopedia was held at the New Horizons in Biochemistry & Molecular Biology Education Conference, jointly organised by FEBS and IUBMB and hosted at the Weizmann Institute of Science.
- June, 2016: Animate any Proteopedia scene in Powerpoint.
- June, 2016: Proteopedia uses the Biological Assemblies from PDBe as the default scenes for all PDB entry pages. Thus, based on the curation by EBI (host for PDBe) the most biologically significant structure is shown.
- June, 2015: Award Ceremony for the the Proteopedia Award at the ICSG2015 - Deep Sequencing Meets Structural Biology, awarded on 10-Jun-2015 at the Weizmann Institute of Science
- December, 2014, Talking about Proteopedia on 12/04/14-12/06/14, a live online talk organised by DivCHED CCCE: Committee on Computers in Chemical Education
- October, 2014 Course in Spanish/English on Proteopedia and its uses to study, display and teach macromolecules.
- How to create fast loading pages in Proteopedia.
- How to be as safe as possible with Java
- Proteopedia on iPads!
- What version of Jmol is running?
- Proteopedia status
- Awards
- ↑ [1], Protein Database (PDBsum): 1ema. European Bioinformatics (EBI); 2009.
- ↑ [2], Yang F, Moss LG, Phillips GN Jr. 1996. The molecular structure of green fluorescent protein. Biotechnology. 14: 1246-1251. DOI 10.1038/nbt1096-1246.
- ↑ Cite error: Invalid
<ref> tag;
no text was provided for refs named Tsien
- ↑ Castro C, Johnson RJ, Kieffer B, Means JA, Taylor A, Telford J, Thompson LK, Sussman JL, Prilusky J, Theis K. A practical guide to teaching with Proteopedia. Biochem Mol Biol Educ. 2021 Jun 3. doi: 10.1002/bmb.21548. PMID:34080750 doi:http://dx.doi.org/10.1002/bmb.21548
|
The Scoreboard
|
Score based on pages-edited and number-of-edits.
List excludes members of the Proteopedia Team.
All scores...
|
Want To Contribute?
|
Pages are easy to create and edit,
and green links are fun & easy to make!
Step 1:
Step 2:
Step 3:
|
Read The Articles
|
|
|
|
|
|
|
|
