Beta-2 microglobulin
From Proteopedia
Beta-2 microglobulin (B2M) is a component of MHC class I system. B2M associates with MHC class I α chain, CD1 and Qa. Loss of B2M function causes iron excess. For more details, see: Human beta two microglobulin.
3D Structures of β-2 microglobulin
Updated on 25-August-2014
B2M
3na4, 3myz, 3ib4, 3ekc, 3dhj, 3dhm, 3ciq, 2z9t, 2d4d, 2f8o, 1py4, 3ov6, 3tlr, 3tm6, 4fxl - hβ-2-microglobulin (mutant) – human
3qda - hβ-2-microglobulin residues 21-119 (mutant)
2xks, 2xku, 1jnj - hβ-2-microglobulin – NMR
2vb5 - hβ-2-microglobulin (mutant) – NMR
2e8d - hβ-2-microglobulin residues 40-61 - NMR
3low, 2yxf, 2d4f, 1lds - hβ-2-microglobulin
3gbl - β-2-microglobulin residues 1-97 - grass carp
1bmg - bβ-2-microglobulin - bovine
3loz - β-2-microglobulin – synthetic
3o81 - cβ-2-microglobulin - chicken
1cd1 - mβ-2-microglobulin - mouse
B2M in binary complex with MHC
1zs8, 1u58 - mβ-2-microglobulin + mMHC I – mouse
1r3h - mβ-2-microglobulin + mMHC II extracellular domain
2hla, 3hla, 1hla - hβ-2-microglobulin + hMHC I
4gup - hβ-2-microglobulin + hMHC I (mutant)
3p73, 3p77 - cβ-2-microglobulin + cMHC I
1pdq - mβ-2-microglobulin + MCMV M144
1z5l, 3au1 - mβ-2-microglobulin + CD1D
4f7c, 4f7e - bβ-2-microglobulin + CD1D
B2M in binary complex with CD1
3s6c - hβ-2-microglobulin/hCD1E
3t8x - hβ-2-microglobulin + hCD1B
3u0p - hβ-2-microglobulin + hCD1D (mutant)
3ma7, 3ilp, 3ilq, 3g08, 3gml, 3gmm, 3gmn, 3gmo, 3gmp, 3gmq, 3gmr, 1zhn, 3t1f, 4mq7 - mβ-2-microglobulin + CD1D1
2gaz, 2fik - mβ-2-microglobulin + CD1D1 extracellular domain
2akr - mβ-2-microglobulin residues 21-119+ CD1D1 extracellular domain
2h26 - hβ-2-microglobulin + CD1B extracellular domain
3l9r - bβ-2-microglobulin + CD1B3
3jvg - cβ-2-microglobulin + CD1A1 ectodomain
B2M in binary complex with other molecules
1exu - hβ-2-microglobulin + Fc receptor
3fru - rβ-2-microglobulin + Fc receptor - rat
1c16 - mβ-2-microglobulin + protein T22
1a6z - hβ-2-microglobulin + hemochromatosis protein
2x89 - hβ-2-microglobulin + antibody
4kdt - hβ-2-microglobulin + nanobody
3mzt - hβ-2-microglobulin + thioflavin
1pqz - mβ-2-microglobulin + MCMV M144
4iiq, 4l8s, 4l9l, 4lcc, 4lcw - bβ-2-microglobulin + Tc receptor
B2M in ternary complex with MHC
2yf6, 3bew, 4e0r, 4g42, 4g43 – cβ-2-microglobulin + cMHC I α + peptide
2xfx - bβ-2-microglobulin + MHC I α + peptide
3jts, 3jtt, 1zvs, 3rwc, 3rwd, 3rwe, 3rwf, 3rwg, 3rwh, 3rwi, 3rwj - β-2-microglobulin + MHC I α + peptide – Macaca mulatta
3kpn, 3kpo – hβ-2-microglobulin + hMHC I B + peptide
3bev, 1kpr, 1k5n, 3nfn, 3mr9, 3mrb, 3mrc, 3mrd, 3mre, 3mrf, 3mrg, 3mrh, 3mri, 3mrj, 3mrk, 3mrl, 3mrm, 3mrn, 3mro, 3mrp, 3mrq, 3mrr, 3ox8, 3oxr, 3oxs, 2xpg, 3pwj, 3pwl, 3pwn, 3pwp, 2x70, 3o3a, 3o3b, 3o3d, 3o3e, 3lv3, 3ln4, 3ln5, 3myj, 3i6l, 3lkn, 3lko, 3lkp, 3lkq, 3lkr, 3lks, 3hpj, 3i6g, 3i6k, 3mgo, 3mgt, 3l3d, 3l3g, 3l3h, 3l3i, 3l3j, 3l3k, 2x4n, 2x4o, 2x4p, 2x4q, 2x4r, 2x4s, 2x4t, 2x4u, 3lka, 3h7b, 3kpl, 3kpm, 3kpn, 3kpo, 3kpp, 3kpq, 3kpr, 3kps, 3giv, 3hcv, 3d18, 3dtx, 3czf, 3fqn, 3fqr, 3fqt, 3fqu, 3fqw, 3fqx, 3d25, 3bvn, 3dx6, 3dx7, 3dx8, 3dxa, 3bo8, 3bp4, 3bp7, 3bgm, 3bh8, 3bh9, 3bhb, 3b3i, 3b6s, 2rfx, 3bze, 3bzf, 3bw9, 3bwa, 3c9n, 2v2w, 2v2x, 2gt9, 2gtw, 2gtz, 2guo, 2nw3, 2fyy, 2fz3, 2hn7, 2cik, 2git, 2hjk, 2hjl, 2h6p, 2d31, 2c7u, 2bck, 2a83, 2axf, 2axg, 2bvo, 2bvp, 2bvq, 1s8d, 1t1w, 1t1x, 1t1y, 1t1z, 1t20, 1t21, 1t22, 1s7q, 1zsd, 2bsr, 2bss, 2bst, 1zhk, 1zhl, 1tvb, 1tvh, 1xr8, 1xr9, 1w0v, 1w0w, 1xh3, 1uxs, 1uxw, 1s9w, 1s9x, 1s9y, 1q94, 1qvo, 1n2r, 1ogt, 1qew, 1jge, 1k5n, 1i7r, 1i7t, 1i7u, 1jf1, 1jht, 1i4f, 1e27, 1e28, 1i1y, 1i1f, 1qqd, 1mhe, 1b0g, 1a9b, 1a9e, 1a1m, 1a1n, 1a1o, 1tmc, 2clr, 1hhg, 1hhh, 1hhi, 1hhj, 1hhk, 1hsb, 1hsa, 3kla, 3giv, 3d18, 3bxn, 1x7q, 1ydp, 1sys, 1of2, 1jgd, 1eey, 1eez, 1duy, 1duz, 1agb, 1agc, 1agd, 1age, 1agf, 3am8, 3qfd, 3rew, 3rl1, 3rl2, 3skm, 3sko, 3utq, 3uts, 3utt, 3vfm, 3vfn, 3vfo, 3vfp, 3vfr, 3vfs, 3vft, 3vfu, 3vfv, 3vfw, 3vh8 ,2ypk, 3spv, 3tid, 3tie, 3to2, 3upr, 3v5d, 3v5h, 3v5k, 3vcl, 3vri, 3vrj, 4f7m, 4f7p, 4f7t, 4gks, 4i4w, 3w39, 4g8i, 4g9d, 4jqv, 4jqx, 4k7f, 1b0r, 3vxm, 3vxn, 3vxo, 3vxp, 3vxr, 3vxs, 3vxu, 3w0w, 4hwz, 4hx1, 4i48, 4nqv, 4nqx - hβ-2-microglobulin + hMHC I α + peptide
4l29, 4l3c - hβ-2-microglobulin + hMHC I α + NY-ES01
1ktl, 3kww, 3h9h, 3ixa, 3gso, 3gsq, 3gsr, 3gsu, 3gsv, 3gsw, 3gsx, 3ft2, 3ft3, 3ft4, 2av1, 2av7, 1cg9, 1m05, 1m6o, 1kpr, 1ktl, 3kyn, 3kyo, 1qr1 - β-2-microglobulin + hMHC I α (mutant) + peptide
1syv, 1n2r - β-2-microglobulin + hMHC I + hMHC II peptide
1kjv, 1kjm, 1ed3 – rβ-2-microglobulin + MHC I α + peptide
3bev, 3bew, 2yf6, 2yf1, 2yez, 2yf5 - cβ-2-microglobulin + cMHC I α + peptide
1kbg, 3l3h, 3ftg, 3e6f, 3ecb, 3ch1, 3cch, 3cc5, 3cpl, 2zsv, 2zsw, 2zok, 2zol, 3buy, 2ve6, 2e7l, 2fo4, 2cii, 2fwo, 2f74, 1zt1, 1zt7, 1vgk, 1yn6, 1yn7, 1zhb, 1wbx, 1wby, 1wbz, 1rjy, 1rjz, 1rk0, 1rk1, 1t0m, 1t0n, 1s7q, 1s7r, 1s7s, 1s7t, 1s7u, 1s7v, 1s7w, 1s7x, 1lk2, 1kpu, 1kpv, 1n3n, 1nan, 1n59, 1n5a, 1ffn, 1ffo, 1ffp, 1g7p, 1g7q, 1lek, 1leg, 1inq, 1juf, 1k8d, 1jpf, 1jpg, 1fg2, 1qlf, 1bz9, 1kbg, 1hoc, 2mha, 1vad, 1vac, 3fol, 3fom, 3fon, 1ce6, 1osz, 1bii, 1ld9, 2vaa, 2vab, 3p4m, 3p4n, 3p4o, 3p9l, 3p9m, 3pab, 3pwu, 3pwv, 3quk, 3qul, 3rol, 3roo, 3vj6, 1ldp, 3tbs, 3tbt, 3tbv, 3tbw, 3tbx, 3tby, 4huu, 4huv, 4huw, 4hux, 4hv8, 4nsk - mβ-2-microglobulin + mMHC I + peptide
2qri, 3nwm - mβ-2-microglobulin/mMHC I/peptide
2qrs, 2qrt - mβ-2-microglobulin/mMHC I (mutant )/peptide
1mhc, 2clv, 2clz, 1fzj, 1fzk, 1fzm, 1fzo, 1ddh, 4iho, 4l8b, 4l8c, 4l8d – mβ-2-microglobulin + mMHC I (mutant) + peptide
1ypz - mβ-2-microglobulin + mMHC II + T cell receptorbr />
4l4t, 4l4v - hβ-2-microglobulin + hMHC I + T cell receptor
3qq3, 3qq4 - β-2-microglobulin + MHC I + peptide - pig
4gkn - β-2-microglobulin + MHC I + peptide – gorilla
1nez - mβ-2-microglobulin + mMHC I + CD8 α chain
B2M in ternary complex with CD1
3qux, 3quy, 3quz, 3o8x, 3o9w, 4mng - mβ-2-microglobulin + T cell receptor + CD1D1
2po6, 3vwj, 3vwk, 4en3, 3sdx, 3tzv, 4lhu - hβ-2-microglobulin + T cell receptor + CD1D1
3dbx - cβ-2-microglobulin + CD1-2 + fatty acid
1zhn - mβ-2-microglobulin + CD1D1 + phosphatidylcholine
1zt4 - mβ-2-microglobulin + CD1D1 + ceramide derivative
3qi9, 3scm, 3sda, 3sdc, 3ta3, 3tn0, 3to4, 3tvm, 3sdd, 4elm, 3rtq, 3rzc, 4ei5, 4apq - mβ-2-microglobulin + T cell receptor + CD1D1
3ubx, 4irj, 4irs - mβ-2-microglobulin + FAB + CD1D1
1xz0 - hβ-2-microglobulin + CD1A + lipopeptide
1onq - hβ-2-microglobulin + CD1A + sulfatide
1uqs - hβ-2-microglobulin + CD1B + glycolipid
1gzp, 1gzq - hβ-2-microglobulin + CD1B + ceramide derivative
4ei5 - mβ-2-microglobulin + CD1D1 + T cell receptor
B2M in ternary complex with other molecules
1i1a, 1frt - rβ-2-microglobulin + Fc receptor + Fc fragment
1de4 - hβ-2-microglobulin + hemochromatosis protein + transferring receptor
3m17, 3m1b - hβ-2-microglobulin + FcRn+ peptide
4k71, 4n0f, 4n0u - hβ-2-microglobulin + serum albumin + Igg receptor P51
B2M in quaternary complex with MHC
3qdg, 3qdj, 3qdm, 3qeq, 3mv7, 3mv8, 3mv9, 3h9s, 3gsn, 3d39, 3d3v, 3ffc, 2vlj, 2vlk, 2vll, 2vlr, 2j8u, 2p5e, 2p5w, 2pye, 2gj6, 2f54, 2esv, 2bnq, 2bnr, 1lp9, 1oga, 1mi5, 1qrn, 2nx5, 2ak4, 1qse, 1qsf, 1bd2, 1ao7, 2ypl, 4g8g, 4g9f, 4jrx, 4jry - hβ-2-microglobulin + hMHC I α + T cell receptor + peptide
3kxf, 3mv8, 2jcc, 2uwe - hβ-2-microglobulin + hMHC I α (mutant) + T cell receptor + peptide
3sjv - hβ-2-microglobulin + hMHC I α + T cell receptor + peptide
2f53 - hβ-2-microglobulin (mutant) + hMHC I α + T cell receptor + peptide
1p7q, 1im9 - hβ-2-microglobulin + hMHC I α + leukocyte immunoglobulin-like receptor + peptide
2dyp - hβ-2-microglobulin + hMHC I α (mutant) + leukocyte immunoglobulin-like receptor + peptide
3qzw, 3dmm, 1bqh, 1akj - hβ-2-microglobulin + hMHC I α + CD8 α + peptide
1im3 - hβ-2-microglobulin + hMHC I α + cytomegalovirus protein US2 + peptide
3cii, 3cdg - hβ-2-microglobulin + hMHC I α + CD94 ectodomain + NKG2A/NKG2B integral membrane protein + peptide
3hae, 3gjf, 3cvh, 1w72 - hβ-2-microglobulin + hMHC I α + antibody + peptide
1g6r, 2ckb, 3pqy, 2z31, 1nam, 1mwa, 1g6r, 2ckb, 2ol3, 1kj2, 1kj3, 1fo0 - mβ-2-microglobulin + mMHC I + T cell receptor + peptide
2oi9, 3rgv, 3c8k - mβ-2-microglobulin + mMHC I (mutant) + T cell receptor + peptide
1p1z, 1p4l, 1qo3, 1efx - mβ-2-microglobulin + mMHC I + T cell receptor + peptide
3o4l - hβ-2-microglobulin +MHC I + BSLF2/BMLF1 + T cell receptor
4mnq - hβ-2-microglobulin +MHC I + telomerse reverse transcriptase + T cell receptor
4eup, 4euq, 4jfd, 4jfe, 4jff, 4jfo, 4jfp, 4jfq - hβ-2-microglobulin +MHC I + JKF6 + melanoma peptide
4ftv - hβ-2-microglobulin +MHC I + A6 + protein TAX-1 peptide
3hg1 - hβ-2-microglobulin +MHC I + cancer/MART-1+ T cell receptor
3gjf - hβ-2-microglobulin + hMHC I + antibody + peptide
3qfj - hβ-2-microglobulin + hMHC I + A6 + peptide
4e5x - hβ-2-microglobulin + hMHC I + E3 glycoprotein + peptide
4hkj - hβ-2-microglobulin + hMHC I + CPXV203 protein + peptide
4m8v - hβ-2-microglobulin + hMHC I + killer cell Igg-like receptor + peptide
B2M in quaternary complex with CD1
2q7y - mβ-2-microglobulin + CD1D1 + ceramide derivative + fatty acid
3arb, 3ard, 3are, 3arf, 3arg, 3he6, 3he7, 3huj - mβ-2-microglobulin + T cell receptor NKT + CD1D1 + ceramide derivative
3rug - mβ-2-microglobulin + CD1D1 + VALPHA10-Vβ8
B2M in quaternary complex with other molecules
3d2u - hβ-2-microglobulin + UL18 + leukocyte immunoglobulin-like receptor + peptide
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