We apologize for Proteopedia being slow to respond. For the past two years, a new implementation of Proteopedia has been being built. Soon, it will replace this 18-year old system. All existing content will be moved to the new system at a date that will be announced here.

Troponin

From Proteopedia

Revision as of 12:03, 15 December 2014 by Michal Harel (Talk | contribs)

(diff) ←Older revision | Current revision (diff) | Newer revision→ (diff)

Jump to: navigation, search

Template:STRUCTURE 1yv0

Troponin (Tn) is a regulatory protein in muscle contraction. It contains 3 subunits:

TnC causes conformational change in TnI when it binds to calcium ions. For more details on TnC see Role of Troponin C in decreased muscle sensitivity to calcium.
TnT binds to tropomyosin.
TnI binds to actin which is found in thin muscle filaments.

See additional details in Human Cardiac Troponin C.