Pharmaceutical Drugs
From Proteopedia
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Revision as of 08:42, 9 January 2025
The Pharmaceutical industry is one of the world’s largest industries, grossing well over $300 billion in the United States alone. Understanding how the drugs the pharma industry develops work and different characteristics of these compounds is important to nearly everyone as 50% of the US population takes at least one prescription medication regularly and nearly everyone takes a pharmaceutical pill at some point in their life.[1] See also WHO Model Lists of Essential Medicines. The following is a growing list of pharmaceutical compounds organized by disorder. 
See Pharmaceutical Drug Targets for a list of drug targets organized by disease. 
The majority of all modern medicinal drugs target members of the superfamily of proteins called the G protein-coupled receptors or GPCRs[2][3].
Treatments
The following is a list of pharmaceutical treatments for various diseases, organized by disorder. Each entry highlights general information about the therapeutic, pharmacokinetic data comparisons within its drug class, and a structural analysis explaining how the drug compound functions in vivo.
Alzheimer's Disease | 
Bacterial Infection | 
Cancer | 
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Depression | 
Diabetes | 
Erectile Dysfunction | 
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Hypercholeseterolemia | 
Hypertension | 
HIV | 
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Inflammation & Arthritis | 
Influenza | 
Opioid drugs | 
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Viral diseases | 
Asthma | 
Various diseases | 
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References
- ↑ http://www.npr.org/blogs/health/2010/09/03/129626052/a-portrait-of-health-prescription-drugs-in-america
 - ↑ Overington JP, Al-Lazikani B, Hopkins AL. How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. PMID:17139284 doi:10.1038/nrd2199
 - ↑ Peeters MC, van Westen GJ, Li Q, IJzerman AP. Importance of the extracellular loops in G protein-coupled receptors for ligand recognition and receptor activation. Trends Pharmacol Sci. 2011 Jan;32(1):35-42. PMID:21075459 doi:10.1016/j.tips.2010.10.001
 
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David Canner, Alexander Berchansky, Michal Harel, Karsten Theis, Wayne Decatur
