Pharmaceutical Drugs
From Proteopedia
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[[Image: Nexium.jpg|160px|right|thumb|AstraZeneca’s Nexium]] | [[Image: Nexium.jpg|160px|right|thumb|AstraZeneca’s Nexium]] | ||
| - | The Pharmaceutical industry is one of the world’s largest industries, grossing well over $300 billion in the United States alone. Understanding how the drugs the pharma industry develops work and different characteristics of these compounds is important to nearly everyone as 50% of the US population takes at least one prescription medication regularly and nearly everyone takes a pharmaceutical pill at some point in their life.<ref>http://www.npr.org/blogs/health/2010/09/03/129626052/a-portrait-of-health-prescription-drugs-in-america</ref> The following is a growing list of pharmaceutical compounds organized by disorder. | + | The Pharmaceutical industry is one of the world’s largest industries, grossing well over $300 billion in the United States alone. Understanding how the drugs the pharma industry develops work and different characteristics of these compounds is important to nearly everyone as 50% of the US population takes at least one prescription medication regularly and nearly everyone takes a pharmaceutical pill at some point in their life.<ref>http://www.npr.org/blogs/health/2010/09/03/129626052/a-portrait-of-health-prescription-drugs-in-america</ref> See also [[WHO Model Lists of Essential Medicines]]. The following is a growing list of pharmaceutical compounds organized by disorder. |
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==[[Alzheimer's Disease]]== | ==[[Alzheimer's Disease]]== | ||
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| - | ==[[Antifungal]]== | ||
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{{:Treatments:Alzheimer's Disease}} | {{:Treatments:Alzheimer's Disease}} | ||
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| - | {{:Treatments:Antifungal}} | ||
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| - | ==Opioid drugs== | + | ==[[Opioids|Opioid drugs]]== |
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| + | ==Viral diseases== | ||
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| + | <td style="width:33%;border-width:1px; border-style:inset; text-align:center; background:#F1F2FC"> | ||
| + | ==Asthma== | ||
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| + | ==Various diseases== | ||
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| + | {{:Treatments:Viral diseases}} | ||
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| + | {{:Treatments:Asthma}} | ||
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| + | {{:Treatments:Other diseases}} | ||
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Current revision
The Pharmaceutical industry is one of the world’s largest industries, grossing well over $300 billion in the United States alone. Understanding how the drugs the pharma industry develops work and different characteristics of these compounds is important to nearly everyone as 50% of the US population takes at least one prescription medication regularly and nearly everyone takes a pharmaceutical pill at some point in their life.[1] See also WHO Model Lists of Essential Medicines. The following is a growing list of pharmaceutical compounds organized by disorder.
See Pharmaceutical Drug Targets for a list of drug targets organized by disease.
The majority of all modern medicinal drugs target members of the superfamily of proteins called the G protein-coupled receptors or GPCRs[2][3].
Treatments
The following is a list of pharmaceutical treatments for various diseases, organized by disorder. Each entry highlights general information about the therapeutic, pharmacokinetic data comparisons within its drug class, and a structural analysis explaining how the drug compound functions in vivo.
Alzheimer's Disease |
Bacterial Infection |
Cancer |
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Depression |
Diabetes |
Erectile Dysfunction |
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Hypercholeseterolemia |
Hypertension |
HIV |
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Inflammation & Arthritis |
Influenza |
Opioid drugs |
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Viral diseases |
Asthma |
Various diseases |
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References
- ↑ http://www.npr.org/blogs/health/2010/09/03/129626052/a-portrait-of-health-prescription-drugs-in-america
- ↑ Overington JP, Al-Lazikani B, Hopkins AL. How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. PMID:17139284 doi:10.1038/nrd2199
- ↑ Peeters MC, van Westen GJ, Li Q, IJzerman AP. Importance of the extracellular loops in G protein-coupled receptors for ligand recognition and receptor activation. Trends Pharmacol Sci. 2011 Jan;32(1):35-42. PMID:21075459 doi:10.1016/j.tips.2010.10.001
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David Canner, Alexander Berchansky, Michal Harel, Karsten Theis, Wayne Decatur
