Pharmaceutical Drugs

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Revision as of 04:39, 24 April 2011

AstraZeneca’s Nexium
AstraZeneca’s Nexium

The Pharmaceutical industry is one of the world’s largest industries, grossing well over $300 billion in the United States alone. Understanding how the drugs the pharma industry develops work and different characteristics of these compounds is important to nearly everyone as 50% of the US population takes at least one prescription medication regularly and nearly everyone takes a pharmaceutical pill at some point in their life.[1] The following is a growing list of pharmaceutical compounds organized by disorder.

See Pharmaceutical Drug Targets for a list of drug targets organized by disease.

Treatments

The following is a list of pharmaceutical treatments for various diseases, organized by disorder. Each entry highlights general information about the therapeutic, pharmacokinetic data comparisons within its drug class, and a structural analysis explaining how the drug compound functions in vivo.

Alzheimer's Disease

Bacterial Infection

Cancer
Acetylcholinesterase Inhibitors
Antagonists at glutamatergic NMDA receptors
Antibiotics
Anti-ulcer antibiotics
Beta-lactam antibiotics

See Beta-lactam antibiotics, Penams

Anti-CD20 Monoclonal Antibody
Anti-melanoma Monoclonal Antibody

See Treatment of multiple myeloma

Anti-prostate cancer
Anti-myeloma
Anti-acute lymphocytic leukemia
Anti-non-small cell lung cacinoma
B-Raf Kinase Inhibitor
  • Zelboraf - Generic: Vemurafenib (Formerly: PLX-4032)
Chemotherapy
Dihydrofolate Reductase Inhibitor
Epidermal Growth Factor Receptor Inhibitors
Estrogen Receptor Modulator
mTOR inhibitor
  • Rapamune - Generic: Sirolimus (Rapamycin)
  • Afinitor - Generic: Everolimus
  • Torisel - Generic: Temsirolimus
Multiple Receptor Tyrosine kinase (VEGFR, PDGFR, EGFR, KIT, Abl, RAF kinase) Inhibitors

See Treatment of chronic myelogenous leukemia, Treatment of hepatocellular carcinoma, Treatment of renal cell carcinoma, Treatment of gastrointestinal stromal tumor, VEGFR inhibitors and Tyrosine-kinase inhibitors.

Vascular Endothelial Growth Factor Inhibitor
Poly ADP ribose polymerase (PARP) inhibitors
Cyclin-dependent kinases inhibitors

See also Anti-cancer drugs, Anticancer drugs and RAF kinase inhibitors

Diabetes

Erectile Dysfunction

Hypercholesterolemia
Insulin
Dipeptidyl peptidase IV Inhibitor
Peroxisome Proliferator-Activated Receptor Agonist
Glucagon-like peptide-1 (GLP-1) agonist
Mechanism is not completely understood
Inhibitors of the sodium glucose co-transporter-2 (SGLT-2)
Phosphodiesterase Type 5 Inhibitor
  • Cialis - Generic: Tadalafil
  • Levitra - Generic: Vardenafil
  • Viagra - Generic: Sildenafil
HMG-CoA Reductase Inhibitors (Statins)
Niemann-Pick C1-like 1 (NPC1L1) protein blocker

Hypertension

HIV

Inflammation & Arthritis
Angiotensin-Converting Enzyme Inhibitors
β-Adrenergic Receptor Antagonists
Ionotropic Glutamate Receptors
Inhibitors of neprilysin
Renin inhibitors
Angiotensin II receptor antagonist
Chemokine Receptor Type 5 (CCR5) Inhibitors
  • Selzentry - Generic: Maraviroc
HIV-Protease Inhibitors
Non-Nucleoside Reverse Transcriptase Inhibitors
Nucleoside Analog Reverse Transcriptase Inhibitors
  • Baraclude - Generic: Entecavir
  • Emtriva - Generic: Emtricitabine
  • Epivir - Generic: Lamivudine
  • Hivid - Generic: Zalcitabine
  • Retrovir - Generic: Zidovudine
  • Videx - Generic: Didanosine
  • Viread - Generic: Tenofovir
  • Zerit - Generic: Stavudine
  • Ziagen - Generic: Abacavir
Retroviral Integrase Inhibitors
Cytochrome P450 inhibitors
Combinations


Cyclooxygenase Inhibitors
Phospholipase A2 Inhibitors
  • Voltaren - Generic: Diclofenac also may inhibit phospholipase A2 as part of its mechanism of action.

Inflammation & Arthritis

Influenza

--
Cyclooxygenase Inhibitors
Phospholipase A2 Inhibitors
  • Voltaren - Generic: Diclofenac also may inhibit phospholipase A2 as part of its mechanism of action.
M2 Proton Channel Inhibitors
Neuraminidase Inhibitors


References

  1. ↑ http://www.npr.org/blogs/health/2010/09/03/129626052/a-portrait-of-health-prescription-drugs-in-america


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