User:Alexander Berchansky
From Proteopedia
(Difference between revisions)
| Line 91: | Line 91: | ||
*[[Methotrexate]] | *[[Methotrexate]] | ||
*[[Urease]] | *[[Urease]] | ||
| + | *[[Phosphoglycerate Kinase]] | ||
Revision as of 13:38, 4 July 2018
Dr. Alexander Berchansky, Ph.D., Israel Structural Proteomics Center, Weizmann Institute of Science
Interesting pages:
- Acetylcholinesterase
- AChE inhibitors and substrates
- Mutations in BRCA1/BARD1 RING-domain heterodimer
- Mutations in Brca1 BRCT Domains
- Missense Mutations in Phenylalanine Hydroxylase
- A hydrogen-bonding network formed by the B10-E7-E11 residues of a truncated hemoglobin from Tetrahymena pyriformis is critical for stability of bound oxygen and nitric oxide detoxification
- Phosphofructokinase (PFK)
- Alcohol dehydrogenase
- Beta-glucosidase
- Flexibility of the flap in the active site of BACE1 as revealed by crystal structures and molecular dynamics simulations
- A DNA structural alphabet provides new insight into DNA flexibility
- Crystal structure of ADL1, a plant-specific homologue of the universal diaminopimelate amino transferase enzyme of lysine biosynthesis
- Structure of recombinant human carboxylesterase 1 isolated from whole cabbage looper larvae
- Fine tuning of chlorophyll spectra by protein-induced ring deformation
- Xanthine dehydrogenase
- N-Butylisocyanide Oxidation at the [NiFe4S4OHx]-cluster of CO Dehydrogenase
- Multifaceted SlyD from Helicobacter pylori: implication in [NiFe] hydrogenase maturation
- Potent Inhibition of Dinuclear Zinc(II) Peptidase, an Aminopeptidase from Aeromonas proteolytica, by 8-Quinolinol Derivatives: Inhibitor Design Based on Zn2+ Fluorophores, Kinetic, and X-ray Crystallographic Study
- Laue Crystal Structure of Shewanella oneidensis Cytochrome c Nitrite Reductase from a High-yield Expression System
- Peptidylglycine α-Hydroxylating Monooxygenase (PHM)-coordination of peroxide to CuM center. Structural and computational study
- Solution structure and dynamics of human S100A14
- The crystal structure of Sporosarcina pasteurii urease in a complex with citrate provides new hints for inhibitor design
- The mechanism of copper uptake by tyrosinase from Bacillus megaterium
- The crystal structure of an extracellular catechol oxidase from the ascomycete fungus Aspergillus oryzae
- Selectivity of Ni(II) and Zn(II) binding to Sporosarcina pasteurii UreE, a metallo-chaperone in the urease assembly: a calorimetric and crystallographic study
- Solution structure and metal ion binding sites of the human CPEB3 ribozyme's P4 domain
- Synthesis, characterization and binding properties towards CT-DNA and Lipoxygenase, of mixed ligand silver(I) complexes with 2-mercapto-thiazole and its derivatives and triphenylphosphine.
- Fluoride inhibition of Sporosarcina pasteurii urease: structure and thermodynamics
- Aromatic aldehydes at the active site of Aldehyde Oxidoreductase from Desulfovibrio gigas: Reactivity and Molecular Details of the Enzyme-Substrate and Enzyme-Product Interactions
- Crystallographic studies of [NiFe]-hydrogenase mutants: towards consensus structures for the elusive unready oxidized states
- High-resolution crystal structure of Z-DNA in complex with Cr3+ cations
- Structural Characterization of Metal Binding to a Cold-adapted Frataxin
- Conformational control of the binding of diatomic gases to cytochrome c’
- Analyzing the Catalytic Role of Active Site Residues in the Fe-Type Nitrile Hydratase from Comamonas testosteroni Ni1
- Structural characterization of zinc-bound Zmp1, a zinc-dependent metalloprotease secreted by Clostridium difficile
- Structural evidence for Arabidopsis glutathione transferase AtGSTF2 functioning as a transporter of small organic ligands
- Crystal structure of porcine pancreatic phospholipase A2 in complex with 2-methoxycyclohexa-2-5-diene-1,4-dione
- A DNA Structural Alphabet Distinguishes Structural Features of DNA Bound to Regulatory Proteins and in the Nucleosome Core Particle
- Structural and kinetic studies of imidazole binding to two members of the cytochrome c6 family reveal an important role for a conserved heme pocket residue
- Protein and metal cluster structure of the wheat metallothionein domain γ-Ec-1. The second part of the puzzle.
- Ferredoxin
- A Cryo-Crystallographic Time Course for Peroxide Reduction by Rubrerythrin from Pyrococcus furiosus
- Cyt1Aa Toxin: High Resolution Structure Reveals Implications for its Membrane-Perforating Function
- Catalytic metal ion rearrangements underline promiscuity and evolvability of a metalloenzyme
- Structure of estradiol metal chelate and estrogen receptor complex: The basis for designing a new class of SERMs
- Structural and functional insights into a dodecameric molecular machine – The RuvBL1/RuvBL2 complex
- Automated computational design of human enzymes for high bacterial expression and stability
- Antiviral Activity of 3(2H)- and 6-Chloro-3(2H)-Isoflavenes against Highly Diverged, Neurovirulent Vaccine-Derived, Type2 Poliovirus Sewage Isolates
- Structural Basis of Enzymatic Activity for the Ferulic Acid Decarboxylase (FADase) from Enterobacter sp. Px6-4
- Structural and functional characterization of the interaction of the photosensitizing probe methylene blue with Torpedo californica acetylcholinesterase
- The Impact of Crystallization Conditions on Structure-Based Drug Design: a Case Study on the Methylene Blue/Acetylcholinesterase Complex
- Structural basis of transcription activation
- Promiscuous Protein Binding as a Function of Protein Stability
- An Insight to the Dynamics of Conserved Water Mediated Salt Bridge Interaction and Inter-Domain Recognition in hIMPDH Isoforms
- Elucidation by NMR solution of neurotensin in Small Unilamellar Vesicle environment: molecular surveys for neurotensin receptor recognition
- Dominant-negative Effects in Prion Diseases: Insights from Molecular Dynamics Simulations on Mouse Prion Protein Chimeras
- Influence of divalent magnesium ion on DNA: molecular dynamics simulation studies
- Evidence-based docking of the urease activation complex
- Carbon monoxide binding to the heme group at the dimeric interface modulates structure and copper accessibility in the Cu,Zn superoxide dismutase from Haemophilus ducreyi: in silico and in vitro evidences
- Para-(benzoyl)-phenylalanine as a potential inhibitor against LpxC of Leptospira spp.: Homology modeling, docking and molecular dynamics study
- Drug resistance mechanism of PncA in Mycobacterium Tuberculosis
- Mechanism of BAG1 repair on Parkinson’s disease-linked DJ1 mutation
- Traditional Chinese medicine as dual guardians against hypertension and cancer?
- The molecular origin of the MMR-dependent apoptosis pathway from dynamics analysis of MutSα-DNA complexes
- The extracellular subunit interface of the 5-HT3 receptors: a computational alanine scanning mutagenesis study
- DNA Conformation and Energy in Nucleosome Core: A Theoretical Approach
- Molecular modeling study for conformational changes of Sirtuin 2 due to substrate and inhibitor binding
- Crystal structure of the CN-hydrolase SA0302 from the pathogenic bacterium Staphylococcus aureus belonging to the Nit and NitFhit Branch of the nitrilase superfamily
- Insight into TPMT*23 Mutation Mis-folding Using Molecular Dynamics Simulation and Protein Structure Analysis
- Identification of structural motifs in the E2 glycoprotein of Chikungunya involved in virus - host interaction
- Molecular dynamics simulations of the thermal stability of tteRBP and ecRBP
- Investigation on the Site-Selective Binding of Bovine Serum Albumin by Erlotinib Hydrochloride
- Interhelical loops within the bHLH domain are determinant in maintaining TWIST1-DNA complexes
- Investigation of Silent Information Regulator 1 (Sirt1) Agonists from Traditional Chinese Medicine
- Han ethnicity-specific type 2 diabetic treatment from traditional Chinese medicine?
- Conformational dynamics of full-length inducible human Hsp70 derived from microsecond molecular dynamics simulations in explicit solvent
- Non-specificity and synergy at the binding site of the carboplatin-induced DNA adduct via molecular dynamics simulations of the MutSα-DNA recognition complex
- A Possible Strategy against Head and Neck Cancer: In Silico. Investigation of Three-in-One inhibitors
- Structural Insights into the South African HIV-1 Subtype C Protease: Impact of hinge region dynamics and flap flexibility in drug resistance
- Memory-Enhancement by Traditional Chinese Medicine?
- The remarkable efficiency of a Pin-II proteinase inhibitor sans two conserved disulfide bonds is due to enhanced flexibility and hydrogen-bond density in the reactive loop
- Traditional Chinese medicine application in HIV: An in silico study
- Molecular Mechanism of HIV-1 gp120 Mutations That Reduce CD4 Binding Affinity
- Cytochrome c
- Methotrexate
- Urease
- Phosphoglycerate Kinase
