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1. Image:SHOC2.jpg (0 bytes)
2. Image:SHOC2-MRAS.pdb (0 bytes)
3. Image:SHOC2 MRAS.png (0 bytes)
4. Image:7upi SHOC2.pse (0 bytes)
5. Image:GDP with SHOC2.pdb (0 bytes)
6. Image:SHOC2-PP1C-MRAS Pathway.JPG (0 bytes)
7. Image:SHOC2-PP1C-MRAS Pathway Schematic.png (0 bytes)
8. Image:SHOC2-PP1C-MRAS Schematic.JPG (0 bytes)
9. Image:SHOC2-PP1C-MRAS Surface.JPG (0 bytes)
10. Image:Shoc2.pse (0 bytes)
11. Image:SHoc2-pp1c-mras.jpg (0 bytes)
12. Category:Shoc2 (36 bytes)
    1: List of pages with the keyword Shoc2

Page text matches

1. 9b8d (4,256 bytes)
   14: ..., new effector functions, and conserved roles for SHOC2 and PSMC1 in virus restriction.
2. Sandbox Reserved 1788 (8,222 bytes)
   1: ...tion load='7pui' size='350' side='right' caption='SHOC2-PP1C-MRAS (PDB entry [[7upi]])' scene='95/952718/...
   3: =SHOC2-PP1C-MRAS=
   6: ...Overall cartoon of SHOC2-PP1C-MRAS structure with SHOC2 in pink, PP1C in blue, and MRAs in white.</div></...
   7: ...hatase complex formed by the individual proteins: SHOC2, PP1C, and MRAS. Formation of this complex begins...
   12: == SHOC2 ==
3. Sandbox Reserved 1778 (8,870 bytes)
   9: <scene name='95/952705/Shoc2_mras_interaction/2'>hydrogen bonding</scene>
   10: <scene name='95/952706/Shoc2_mras_interaction/2'>hydrogen bonding</scene>
   12: <scene name='95/952705/Shoc2_pp1c_interaction/1'>PP1C binds</scene>
   13: <scene name='95/952706/Shoc2_pp1c_interaction/3'>PP1C binds</scene>
   15: <scene name='95/952705/Shoc2_rvxf/3'>PVxF motif</scene>
4. Sandbox Reserved 1765 (15,355 bytes)
   1: <scene name='95/952693/Shoc2_gtp_bound_vs_gdp_bound/7'>Text To Be Displayed</s...
   2: =SHOC2-PP1C-MRAS=
   3: ...tion load='1stp' size='340' side='right' caption='SHOC2-MRAS-PP1C Holophosphatase Complex' scene='95/9526...
   11: ...unction. <scene name='95/952695/Shoc2intro/1'>The SHOC2 subunit</scene> uses a crescent shape to enhance ...
   15: In all images and animations, {{Font color|cyan|SHOC2}} will be shown as cyan blue, {{Font color|lime|M...
5. Sandbox Reserved 1766 (21,366 bytes)
   2: =SHOC2-PP1C-MRAS=
   3: ...tion load='1stp' size='340' side='right' caption='SHOC2-MRAS-PP1C Holophosphatase Complex' scene='95/9526...
   6: ...unction. <scene name='95/952694/Shoc2intro/1'>The SHOC2 subunit</scene> uses a crescent shape to enhance ...
   10: In all images and animations, {{Font color|cyan|SHOC2}} will be shown as cyan blue, {{Font color|lime|M...
   15: ...inhibition before Ras and Raf can interact. Since SHOC2-PP1C-MRAS plays such a crucial role in the activa...
6. Sandbox Reserved 1767 (18,951 bytes)
   2: =SHOC2-PP1C-MRAS=
   3: ...ns to allow for MAPK signaling. {{Font color|cyan|SHOC2}} is shown as cyan blue, {{Font color|lime|MRAS}}...
   7: ...unction. <scene name='95/952695/Shoc2intro/1'>The SHOC2 subunit</scene> uses a crescent shape to enhance ...
   11: In all images and animations, {{Font color|cyan|SHOC2}} will be shown as cyan blue, {{Font color|lime|M...
   19: === SHOC2 ===
7. User:Sloan August/Sandbox 1 (1,272 bytes)
   1: =SHOC2-PP1C-MRAS PROTEIN COMPLEX=
   2: ...PI' size='350' frame='true' side='right' caption='SHOC2-PP1C-MRAS Holophosphatase Complex'>
   9: <scene name='95/954044/Shoc2_switch_i_region/1'>SHOC2 Switch I Region</scene>
   12: [[Image:SHOC2.png|350 px|center|thumb|Figure 1]]
   17: === Mechanism of SHOC2-PP1C-MRAS Complex Formation ===
8. User:Katherine Snook/Sandbox 1 (1,391 bytes)
   1: =SHOC2-MRAS-PP1C holoenzyme=
   2: ...pi' size='350' frame='true' side='right' caption='SHOC2-MRAS-PP1C 7upi' scene='95/954076/Random_selection...
   20: === SHOC2:MRAS ===
   21: [[Image:SHOC2_MRAS.png|400 px|right|thumb|Figure 1. The coolest...
9. User:Reagann R. Meyers/ Sandbox 1 (1,760 bytes)
   3: ...pi' size='350' frame='true' side='right' caption='SHOC2-PP1C-MRAS' scene=''>
   16: ===SHOC2-PP1C-MRAS Specifically===
   22: <scene name='95/954077/Gdp_with_mras_and_shoc2/1'>TextToBeDisplayed</scene>
10. User:Emily Landwehr/Sandbox1 (1,457 bytes)
    1: =Structure of SHOC2-PP1C-MRAS Holoenzyme=
    2: ...PI' size='350' frame='true' side='right' caption='SHOC2-PP1C-MRAS Holoenzye. PDB 7UPI' scene='95/954079/A...
    11: ...079/Assignment_scene/2'> The active holoenzyme of SHOC2-PP1C-MRAS. Residues 275-350 are displayed in whit...
    12: ===SHOC2 Cradle===
11. User:Rosa Trippel/Sandbox 1 (1,096 bytes)
    1: =''SHOC2-PP1C-MRas, RAS-RAF Pathway and Signaling Cascade'...
    2: ...pi' size='350' frame='true' side='right' caption='SHOC2-PP1C-MRas, 7upi' scene=''>
    4: [https://proteopedia.org/wiki/index.php/7upi SHOC2-PP1C-MRas Background Information]
    6: === SHOC2 ===
    17: <scene name='95/954050/Residues_45-80/1'>SHOC2 Complex highlighting Residues 45-80</scene>
12. User:Kayla Wilhoite/Sandbox1 (1,203 bytes)
    1: =SHOC2-PP1C-MRAS=
13. User:Inaya Patel/Sandbox 1 (659 bytes)
    1: ...pi' size='350' frame='true' side='right' caption='shoc2 pp1c mras' scene='95/955184/Residues_1-100/1'>
    4: =SHOC2 PP1C MRAS=
    7: [https://proteopedia.org/wiki/index.php/7upi shoc2 pp1c mras proteopedia page]
14. Sandbox Reserved 1777 (16,105 bytes)
    3: ...size='350' side='right' caption='SHOC2-PP1C-MRAS. SHOC2(blue) PP1C(orange) MRAS (green) and metal ions (g...
    5: SHOC2-PP1C-MRAS is a regulatory protein and enzyme comp...
    7: ...tion of RAS/RAF/MEK/ERK pathway after assembly of SHOC2-PP1C-MRAS complex. </div></font>]]
    14: ...([https://www.rcsb.org/structure/7UPI PDB 7upi]). SHOC2 (blue), PP1C (orange) and MRAS (green). </div></...
    15: ...PP1C and MRAS bound within the concave surface of SHOC2, leaving the catalytic site of PP1C and the GTP b...
15. Sandbox Reserved 1776 (6,678 bytes)
    3: ...PI' size='350' frame='true' side='right' caption='SHOC2-PP1C-MRAS holoenzyme complex' scene=''>
    10: SHOC2-PP1C-MRAS is a human enzyme that is involved in r...
    13: ... that PP1C and MRAS occupy the concave surface of SHOC2, leaving the catalytic site of PP1C and the subst...
    16: ...nson, M.C., Izadi, S. et al. Structural basis for SHOC2 modulation of RAS signalling. Nature 609, 400–4...
    20: ...n, Y. et al. Structure–function analysis of the SHOC2–MRAS–PP1C holophosphatase complex. Nature 609...
16. User:Madeline Gilbert/Sandbox 1 (1,375 bytes)
    1: =SHOC2-MRAS-PP1C=
    3: ...tion load='7UPI' size='340' side='right' caption='SHOC2-MRAS-PP1C'>
    8: [https://proteopedia.org/wiki/index.php/7upi SHOC2-MRAS-PP1C]<scene name='95/955187/Leucine-sheets_a...
17. Sandbox Reserved 1789 (10,784 bytes)
    8: ==SHOC2-PP1C-MRAS==
    9: ...tion load='7UPI' size='340' side='right' caption='SHOC2-MRAS-PP1C'>
    13: ...s GDP to GTP, it then assembles with the combined SHOC2 and PP1C. Based on MRAS targeting, PP1C catalyzes...
    15: ...sm.png|200px|center|thumb|Figure 1: Mechanism for Shoc2-MRAS-PP1C]]
    19: === SHOC2 ===
18. Sandbox Reserved 1790 (15,421 bytes)
    1: ...tion load='7pui' size='350' side='right' caption='SHOC2-PP1C-MRAS (PDB entry [[7upi]])' scene='95/952718/...
    3: =SHOC2-PP1C-MRAS=
    6: ...s GDP to GTP, it then assembles with the combined SHOC2 and PP1C. Based on MRAS targeting, PP1C catalyzes...
    10: ==SHOC2==
    11: ...] that is necessary for the LRR fold, giving the SHOC2 its concave structure <ref name="Kwon" />.
19. 9b8e (4,434 bytes)
    14: ..., new effector functions, and conserved roles for SHOC2 and PSMC1 in virus restriction.
20. 7sd0 (4,685 bytes)
    2: ==Cryo-EM structure of the SHOC2:PP1C:MRAS complex==
    11: [https://www.uniprot.org/uniprot/SHOC2_HUMAN SHOC2_HUMAN] Noonan syndrome-like disorder with loose a...
    13: [https://www.uniprot.org/uniprot/SHOC2_HUMAN SHOC2_HUMAN] Regulatory subunit of protein phosphatase ...
    16: ...erence for complex assembly, and uncovers how the SHOC2 scaffold and RAS collectively drive specificity o...
    18: Structural basis for SHOC2 modulation of RAS signalling.,Liau NPD, Johnson M...

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