User:Alexander Berchansky

From Proteopedia

Revision as of 10:47, 13 February 2019

Dr. Alexander Berchansky, Ph.D., Israel Structural Proteomics Center, Weizmann Institute of Science

My interesting pages:

• Acetylcholinesterase
• AChE inhibitors and substrates
• Mutations in BRCA1/BARD1 RING-domain heterodimer
• Mutations in Brca1 BRCT Domains
• Lactate Dehydrogenase
• Human Acetylcholinesterase
• Missense Mutations in Phenylalanine Hydroxylase
• Ferredoxin
• Phosphofructokinase (PFK)
• Alcohol dehydrogenase
• Beta-glucosidase
• Aricept Complexed with Acetylcholinesterase (Hebrew)
• Aricept Complexed with Acetylcholinesterase (Russian)
• Prion
• Canine parvovirus
• Opioids

CRISPR-Cas (under development):

• CRISPR-Cas Part I
• CRISPR-Cas Part II
• CRISPR-Cas9

Classification according to the Wikipedia page CRISPR [1] with additions

CRISPR Class 1 uses a complex of multiple Cas proteins

CRISPR type I (Cas3)

CRISPR type I-A (Cascade) - see CRISPR subtype I-A

CRISPR type I-B (Cascade) - see CRISPR subtype I-B

CRISPR type I-C (Cascade) - see CRISPR subtype I-C

CRISPR type I-D (Cas10d)

CRISPR type I-E (Cascade) - see CRISPR subtype I-E

CRISPR type I-F (Csy1, Csy2, Csy3) - see CRISPR subtype I-F

CRISPR type I-U (GSU0054)

CRISPR type III (Cas10)

CRISPR type III-A (Csm complex) - see CRISPR subtype III-A (Csm complex)

CRISPR type III-B (Cmr complex)

CRISPR type III-C (Cas10 or Csx11)

CRISPR type III-D (Csx10)

CRISPR type Orphan

CRISPR type IV (Csf1)

CRISPR type IV-A

CRISPR type IV-B

CRISPR Class 2 uses a single large Cas protein

CRISPR type II-A - see CRISPR-Cas9

CRISPR type II-B (Cas4)

CRISPR type II-C

CRISPR type V (Cpf1, C2c1, C2c3) - see CRISPR type V

CRISPR type VI (Cas13a (previously known as C2c2), Cas13b, Cas13c, Cas13d) - see CRISPR type VI

• Flexibility of the flap in the active site of BACE1 as revealed by crystal structures and molecular dynamics simulations
• A DNA structural alphabet provides new insight into DNA flexibility
• Crystal structure of ADL1, a plant-specific homologue of the universal diaminopimelate amino transferase enzyme of lysine biosynthesis
• Structure of recombinant human carboxylesterase 1 isolated from whole cabbage looper larvae
• Fine tuning of chlorophyll spectra by protein-induced ring deformation
• A hydrogen-bonding network formed by the B10-E7-E11 residues of a truncated hemoglobin from Tetrahymena pyriformis is critical for stability of bound oxygen and nitric oxide detoxification
• ISC-like [2Fe-2S] ferredoxin (FdxB) dimer from Pseudomonas putida JCM 20004: Structural and electron nuclear double resonance characterization
• N-Butylisocyanide Oxidation at the [NiFe₄S₄OH_x]-cluster of CO Dehydrogenase
• Multifaceted SlyD from Helicobacter pylori: implication in [NiFe] hydrogenase maturation
• Potent Inhibition of Dinuclear Zinc(II) Peptidase, an Aminopeptidase from Aeromonas proteolytica, by 8-Quinolinol Derivatives: Inhibitor Design Based on Zn2+ Fluorophores, Kinetic, and X-ray Crystallographic Study
• Laue Crystal Structure of Shewanella oneidensis Cytochrome c Nitrite Reductase from a High-yield Expression System
• Peptidylglycine α-Hydroxylating Monooxygenase (PHM)-coordination of peroxide to Cu_M center. Structural and computational study
• Solution structure and dynamics of human S100A14
• The crystal structure of Sporosarcina pasteurii urease in a complex with citrate provides new hints for inhibitor design
• The mechanism of copper uptake by tyrosinase from Bacillus megaterium
• The crystal structure of an extracellular catechol oxidase from the ascomycete fungus Aspergillus oryzae
• Selectivity of Ni(II) and Zn(II) binding to Sporosarcina pasteurii UreE, a metallo-chaperone in the urease assembly: a calorimetric and crystallographic study
• Solution structure and metal ion binding sites of the human CPEB3 ribozyme's P4 domain
• Synthesis, characterization and binding properties towards CT-DNA and Lipoxygenase, of mixed ligand silver(I) complexes with 2-mercapto-thiazole and its derivatives and triphenylphosphine.
• Fluoride inhibition of Sporosarcina pasteurii urease: structure and thermodynamics
• Aromatic aldehydes at the active site of Aldehyde Oxidoreductase from Desulfovibrio gigas: Reactivity and Molecular Details of the Enzyme-Substrate and Enzyme-Product Interactions
• Crystallographic studies of [NiFe]-hydrogenase mutants: towards consensus structures for the elusive unready oxidized states
• High-resolution crystal structure of Z-DNA in complex with Cr3+ cations
• Structural Characterization of Metal Binding to a Cold-adapted Frataxin
• Conformational control of the binding of diatomic gases to cytochrome c’
• Analyzing the Catalytic Role of Active Site Residues in the Fe-Type Nitrile Hydratase from Comamonas testosteroni Ni1
• Structural characterization of zinc-bound Zmp1, a zinc-dependent metalloprotease secreted by Clostridium difficile
• Structural evidence for Arabidopsis glutathione transferase AtGSTF2 functioning as a transporter of small organic ligands
• Crystal structure of porcine pancreatic phospholipase A₂ in complex with 2-methoxycyclohexa-2-5-diene-1,4-dione
• A DNA Structural Alphabet Distinguishes Structural Features of DNA Bound to Regulatory Proteins and in the Nucleosome Core Particle
• Structural and kinetic studies of imidazole binding to two members of the cytochrome c6 family reveal an important role for a conserved heme pocket residue
• Protein and metal cluster structure of the wheat metallothionein domain γ-Ec-1. The second part of the puzzle.
• A Cryo-Crystallographic Time Course for Peroxide Reduction by Rubrerythrin from Pyrococcus furiosus
• Cyt1Aa Toxin: High Resolution Structure Reveals Implications for its Membrane-Perforating Function
• Catalytic metal ion rearrangements underline promiscuity and evolvability of a metalloenzyme
• Structure of estradiol metal chelate and estrogen receptor complex: The basis for designing a new class of SERMs
• Structural and functional insights into a dodecameric molecular machine – The RuvBL1/RuvBL2 complex
• Automated computational design of human enzymes for high bacterial expression and stability
• Antiviral Activity of 3(2H)- and 6-Chloro-3(2H)-Isoflavenes against Highly Diverged, Neurovirulent Vaccine-Derived, Type2 Poliovirus Sewage Isolates
• Structural Basis of Enzymatic Activity for the Ferulic Acid Decarboxylase (FADase) from Enterobacter sp. Px6-4
• Structural and functional characterization of the interaction of the photosensitizing probe methylene blue with Torpedo californica acetylcholinesterase
• The Impact of Crystallization Conditions on Structure-Based Drug Design: a Case Study on the Methylene Blue/Acetylcholinesterase Complex
• Structural basis of transcription activation
• Promiscuous Protein Binding as a Function of Protein Stability
• An Insight to the Dynamics of Conserved Water Mediated Salt Bridge Interaction and Inter-Domain Recognition in hIMPDH Isoforms
• Elucidation by NMR solution of neurotensin in Small Unilamellar Vesicle environment: molecular surveys for neurotensin receptor recognition
• Dominant-negative Effects in Prion Diseases: Insights from Molecular Dynamics Simulations on Mouse Prion Protein Chimeras
• Influence of divalent magnesium ion on DNA: molecular dynamics simulation studies
• Evidence-based docking of the urease activation complex
• Carbon monoxide binding to the heme group at the dimeric interface modulates structure and copper accessibility in the Cu,Zn superoxide dismutase from Haemophilus ducreyi: in silico and in vitro evidences
• Para-(benzoyl)-phenylalanine as a potential inhibitor against LpxC of Leptospira spp.: Homology modeling, docking and molecular dynamics study
• Drug resistance mechanism of PncA in Mycobacterium Tuberculosis
• Mechanism of BAG1 repair on Parkinson’s disease-linked DJ1 mutation
• Traditional Chinese medicine as dual guardians against hypertension and cancer?
• The molecular origin of the MMR-dependent apoptosis pathway from dynamics analysis of MutSα-DNA complexes
• The extracellular subunit interface of the 5-HT3 receptors: a computational alanine scanning mutagenesis study
• DNA Conformation and Energy in Nucleosome Core: A Theoretical Approach
• Molecular modeling study for conformational changes of Sirtuin 2 due to substrate and inhibitor binding
• Crystal structure of the CN-hydrolase SA0302 from the pathogenic bacterium Staphylococcus aureus belonging to the Nit and NitFhit Branch of the nitrilase superfamily
• Insight into TPMT*23 Mutation Mis-folding Using Molecular Dynamics Simulation and Protein Structure Analysis
• Identification of structural motifs in the E2 glycoprotein of Chikungunya involved in virus - host interaction
• Molecular dynamics simulations of the thermal stability of tteRBP and ecRBP
• Investigation on the Site-Selective Binding of Bovine Serum Albumin by Erlotinib Hydrochloride
• Interhelical loops within the bHLH domain are determinant in maintaining TWIST1-DNA complexes
• Investigation of Silent Information Regulator 1 (Sirt1) Agonists from Traditional Chinese Medicine
• Han ethnicity-specific type 2 diabetic treatment from traditional Chinese medicine?
• Conformational dynamics of full-length inducible human Hsp70 derived from microsecond molecular dynamics simulations in explicit solvent
• Non-specificity and synergy at the binding site of the carboplatin-induced DNA adduct via molecular dynamics simulations of the MutSα-DNA recognition complex
• A Possible Strategy against Head and Neck Cancer: In Silico. Investigation of Three-in-One inhibitors
• Structural Insights into the South African HIV-1 Subtype C Protease: Impact of hinge region dynamics and flap flexibility in drug resistance
• Memory-Enhancement by Traditional Chinese Medicine?
• The remarkable efficiency of a Pin-II proteinase inhibitor sans two conserved disulfide bonds is due to enhanced flexibility and hydrogen-bond density in the reactive loop
• Traditional Chinese medicine application in HIV: An in silico study
• Molecular Mechanism of HIV-1 gp120 Mutations That Reduce CD4 Binding Affinity
• Book:Structural Proteomics and its Impact on the Life Sciences:6‎
• A cytosine modification mechanism revealed by the ternary complex structure of deoxycytidylate hydroxymethylase from bacteriophage T4 with its cofactor and substrate
• Structure of the AmyC GH13 alpha-amylase from Alicyclobacillus sp, reveals accommodation of starch branching points in the alpha-amylase family
• The crystal structure of the N-acetylglucosamine 2-epimerase from Nostoc sp. KVJ10 reveals the true dimer
• Structure of ISG15 from the bat species Myotis davidii and the impact of interdomain ISG15 interactions on viral protein engagement
• The structure of Mycobacterium tuberculosis HtrA reveals an auto-regulatory mechanism
• Crystal structure and kinetic analyses of a hexameric form of (S)-3-hydroxybutyryl-CoA dehydrogenase from Clostridium acetobutylicum

1. Identification of novel isocytosine derivatives as xanthine oxidase inhibitors from a set of virtual screening hits, Chandrika B-Rao, Asha Kulkarni-Almeida, Kamlesh V. Katkar, Smriti Khanna, Usha Ghosh, Ashish Keche, Pranay Shah, Ankita Srivastava, Vaidehi Korde, Kumar V. S. Nemmani, Nitin J. Deshmukh, Amol Dixit, Manoja K. Brahma, Umakant Bahirat, Lalit Doshi, Rajiv Sharma, H. Sivaramakrishnan http://www.ncbi.nlm.nih.gov/pubmed/22483591

• SUMO
• EPSP synthase
• AMP-activated protein kinase
• Xanthine dehydrogenase
• Nicotinic Acetylcholine Receptor
• Cytochrome c
• Methotrexate
• Kemp elimination catalyst
• Urease
• Phosphoglycerate Kinase
• Plant-derived glucocerebrosidase
• NADH quinone oxidoreductase (NQO1) with inhibitor dicoumarol
• Matrix metalloproteinase
• Amino acid oxidase
• Mutant immunity protein 9 (variant R12-13)
• Acetylcholine binding protein
• Hydroxylase
• Actin
• Torpedo Californica Acetylcholinesterase in complex with an (R)-Tacrine-(10)-Hupyridone inhibitor
• Dronpa
• Major histocompatibility complex
• Mutant immunity protein 9 (variant R12-2)
• Butyrylcholinesterase
• Human acid-beta-glucosidase covalently bound to conduritol B epoxide
• Avidin
• Proteasome
• FK506 binding protein
• Insecticidal delta-endotoxin Cyt2Ba from Bacillus thuringiensis
• Ubiquitin protein ligase
• Catalase
• Albumin
• Aminopeptidase
• Staphylococcal nuclease
• Virus protease
• Asparaginase
• NAC transcription factor
• Kemp eliminase
• NADPH-Cytochrome P450 Reductase
• Prolyl hydroxylase domain
• Neuraminidase
• Carbonic anhydrase
• Carboxypeptidase
• ABC transporter
• Ubiquitin
• Cytochrome P450
• TEM1-beta-Lactamase/beta-lactamase Inhibitor Protein (BLIP)
• Acid beta-glucosidase with N-butyl-deoxynojirimycin
• Treatment of Gaucher disease
• Acyl carrier protein synthase
• Chimeras of alcohol dehydrogenases
• Dihydrodipicolinate synthase
• Directed evolution
• Colicin Immunity Protein
• Human FKBP52
• Opioid receptor
• Acetylcholine
• Heat Shock Proteins
• Dioxygenase
• Flavodoxin
• Phospholipase A2
• Tyrosine kinase
• Cellobiohydrolase
• Acid phosphatase
• Neuroglobin
• Hirudin
• GTP-binding protein
• Aldehyde dehydrogenase
• Delta-endotoxin
• Beta-lactamase
• Estrogen receptor
• DNA-binding protein VirE2 from Agrobacterium tumefaciens complexed with chaperone VirE1
• Alkaline phosphatase
• Cathepsin
• Prolyl Endopeptidase
• Forkhead box protein
• Subtilisin
• Hyaluronidase
• Lysine-specific histone demethylase
• Glycolate oxidase
• Chaperonin
• Nucleoprotein
• Transcriptional activator
• Chitinase
• Cluster of Differentiation CD38
• Tubulin
• SAM-dependent methyltransferase
• Lignin peroxidase
• Gyrase
• Methylesterase
• CAMP-dependent protein kinase
• Plasminogen
• Choline Oxidase
• Thioesterase
• Dopamine receptor
• Mitogen-activated protein kinase kinase
• Kinesin
• Gelsolin
• DNA glycosylase
• Mitogen-activated protein kinase
• Factor VIII
• BtuB
• BLUF domain protein
• Botulinum neurotoxin
• Blue copper oxidase CueO
• Beta-phosphoglucomutase
• Beta-ketoacyl-ACP reductase
• Beta-adrenergic receptor kinase
• Barnase
• Bacteriorhodopsin
• BA42
• Gramicidin
• Horseradish peroxidase
• Azurin
• Avirulence protein
• Autophagy-related protein
• ATP-citrate synthase
• Atlastin
• Catabolite gene activator protein
• Cytochrome bc1 complex
• Lactoferrin
• Glycosyltransferase
• Factor inhibiting HIF
• Ephrin receptor
• Aspartoacylase
• Aspartate carbamoyltransferase
• Proliferating Cell Nuclear Antigen
• Aspartate-semialdehyde dehydrogenase
• Ascorbate peroxidase
• Aromatic amine dehydrogenase
• Arginine kinase
• Antigen 85
• Anti-sigma factor antagonist
• Anthrax protective antigen
• Anthrax edema factor
• Annexin
• Aminotransferase
• Alpha-tubulin N-acetyltransferase
• Alpha-lytic protease
• Aldose Reductase
• Alanine racemase
• Agglutinin
• ADP-ribose pyrophosphatase
• Poly (ADP-ribose) polymerase
• Adenylosuccinate lyase
• Adenosine kinase
• Adenosine deaminase
• Adenosine A2A receptor
• Adaptin
• Acylaminoacyl peptidase
• Acyl carrier protein
• Acyl-CoA dehydrogenase
• Acetylxylan esterase
• Acetyl-CoA carboxylase
• Acetyl-CoA synthetase
• Acetyl-CoA synthase
• Cytochrome c oxidase
• Concanavalin A
• Neurexin
• Histone deacetylase
• Purine repressor
• Protein phosphatase
• Glutamate synthase
• 4-hydroxy-3-methylbut-2-enyl diphosphate reductase
• 6-aminohexanoate-dimer hydrolase
• 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase
• 7,8-dihydro-8-oxoguanine triphosphatase
• Cell division protein
• Carbon monoxide dehydrogenase
• CXC chemokine receptor
• Cyclin-dependent kinase
• 12-oxophytodienoate reductase
• Enoyl-Acyl-Carrier Protein Reductase
• Dihydrolipoamide acetyltransferase
• Alpha-glucosidase
• Apoptotic protease-activating factor
• Arginase
• Adhesin
• Arabinanase
• Gp120
• GMP synthase
• Leukotriene A4 Hydrolase
• Biotin Protein Ligase
• Androgen receptor
• Glutamate dehydrogenase
• 14-3-3 protein
• Fibrin
• 3C protease
• GTPase KRas
• 6-phosphogluconate dehydrogenase
• Mineralocorticoid receptor
• Thyroid hormone receptor
• Progesterone receptor
• Serpin
• Leucine transporter
• Microtubule-associated protein
• Ectonucleotide pyrophosphatase/phosphodiesterase
• Ribosome biogenesis protein
• Liver X receptor
• Nitrophorin
• VprBP
• Growth factor receptor-bound protein
• CREB-binding protein
• Kdo-8-phosphate synthase
• Signal recognition particle receptor
• Liver receptor homolog-1
• Orexin and Orexin receptor
• Spindlin
• Prostaglandin E synthase
• Terminase
• Mandelate racemase/muconate lactonizing enzyme
• GABA(A) receptor-associated protein
• IspG
• Haloperoxidase
• Cytochrome P450 hydroxylase
• Period circadian protein
• Proteinase
• Sialyltransferase
• Neprilysin
• Cholesterol esterase
• Chloramphenicol acetyltransferase
• Thiolase
• CCA-adding enzyme
• Glucose-fructose oxidoreductase
• Tripeptidyl peptidase
• Tryptophan synthase
• Fatty acid synthase
• Glucosamine 6-phosphate synthase
• Rho GTPase activating protein
• Ornithine decarboxylase
• Prostaglandin D synthase
• Prestin
• Polyamine oxidase
• Phosphotransferase
• Phosphodiesterase
• Plexin
• Plasminogen activator
• Plasmid segregation protein ParM
• Phospholipase C
• Phosphoenolpyruvate carboxylase
• Peptide N-glycanase
• Penicillopepsin
• Penicillin acylase
• PCSK9
• Galactose-binding lectin
• Paired box protein
• D-xylose isomerase
• Adrenodoxin reductase
• Methylamine dehydrogenase
• Oligopeptide-binding protein
• Met repressor
• Nuclear receptor coactivator
• Neuropilin
• NADH peroxidase
• Deoxyuridine 5'-triphosphate nucleotidohydrolase
• LDL receptor
• P63
• Galactose oxidase
• Leukotriene B4 hydroxydehydrogenase
• Leukocyte immunoglobulin-like receptor
• Alpha-lactalbumin
• 3-phosphoinositide-dependent protein kinase 1
• 2-isopropylmalate synthase
• Kelch-like protein
• Lactoperoxidase
• Mur ligase
• Calcineurin
• S100 protein
• Ecotin
• Leukotriene C4 synthase
• Jumonji domain-containing protein
• Monooxygenase
• Vanillyl-alcohol oxidase
• Isopropylmalate dehydrogenase
• Tumor necrosis factor
• Tumor necrosis factor receptor
• Mannosidase
• Transthyretin
• Transport inhibitor response 1
• Transducin
• Nitrate reductase
• Nitroreductase
• Dihydroorotate dehydrogenase
• L-rhamnose isomerase
• TRAIL
• Estrogen-related receptor
• Inosine monophosphate dehydrogenase
• Survivin
• UDP-N-acetylglucosamine acyltransferase
• Haptoglobin receptor
• D-alanine-D-alanine ligase
• Glutaminyl cyclase
• Severin
• Carnitine palmitoyltransferase
• Isoaspartyl dipeptidase
• Thiaminase
• Acetylcholinesterase with OTMA
• D275P mutant of alcohol dehydrogenase from protozoa Entamoeba histolytica
• Ferripyoverdine receptor
• Fatty acid-binding protein
• Rho-associated protein kinase
• Endonuclease
• Collagenase (non-MMP)
• Epoxidase
• Ferrochelatase
• Elastase
• Tyrosinase
• N-acetylornithine carbamoyltransferase
• Ornithine carbamoyltransferase
• Pantothenate kinase
• Pantothenate synthetase
• Parvalbumin
• Cephalosporin acylase
• Dipeptidyl peptidase
• Farnesyltransferase
• Farnesyl diphosphate synthase
• Arginine repressor
• Transferrin
• Transketolase
• Dihydropteroate synthase
• Trichodiene synthase
• DAHP synthase
• Trehalulose synthase
• TRNA-guanine transglycosylase
• Cyclophilin
• Cutinase
• Trypanothione reductase
• Trypsin inhibitor
• Tryptase
• Tubulin tyrosine ligase
• Transaldolase
• Urokinase
• Undecaprenyl pyrophosphate synthase
• UDP-galactose 4-epimerase
• Uridine 5'-monophosphate synthase
• Arsenate reductase
• Rac
• Rho GTPase
• Carbamoyl phosphate synthetase
• Dedicator of cytokinesis protein
• Phosphoribosylaminoimidazole carboxylase
• Retinoid isomerohydrolase
• Calcium uptake protein 1
• Abscisic acid receptor
• Apoptosis-inducing factor
• Nucleolin
• Aldo-keto reductase
• SAICAR synthetase
• Prolactin receptor
• Siderocalin
• Latrophilin
• Folypolyglutamate synthase
• WD repeat-containing protein
• Xylosidase
• Uridylate kinase
• Penicillin-binding protein
• Pentaerythritol tetranitrate reductase
• Thymidine kinase
• Thymidylate kinase
• Tissue factor pathway inhibitor
• Thioredoxin Reductase
• Peptidyl-tRNA hydrolase
• Peroxiredoxin
• Phenylethanolamine N-methyltransferase
• Tetracycline repressor protein
• Phenylpyruvate decarboxylase
• Succinate-semialdehyde dehydrogenase
• Spermidine/spermine N-acetyltransferase
• Sulfotransferase
• Phosphomannomutase
• Strictosidine Synthase
• Phosphoenolpyruvate carboxykinase
• Phosphoribosyltransferase
• Phosphoserine aminotransferase
• Phosphoserine phosphatase
• Shikimate kinase
• Shikimate dehydrogenase
• Selectin
• Selenocysteine synthase
• Semaphorin
• Serine palmitoyltransferase
• SAM decarboxylase
• SAM synthetase
• S-adenosylhomocysteine hydrolase
• Plasmepsin
• RNA uridylyltransferase
• Ribosomal protein S6 kinase
• Poly(A) RNA polymerase protein Cid1
• Ribonucleotide reductase
• Phycocyanobilin:ferredoxin oxidoreductase
• Poly (ADP-ribose) glycohydrolase
• Rhomboid protease
• Rhodopsin kinase
• Retinol-binding protein
• Polyneuridine Aldehyde Esterase
• Retinoid X receptor
• Porphobilinogen synthase
• Retinoblastoma-binding protein
• Pyruvate dehydrogenase kinase
• Pyruvate-ferredoxin oxidoreductase
• Pyrroline-5-carboxylate dehydrogenase
• Purine nucleoside phosphorylase
• Proline utilization A
• Protein kinase C
• Nucleoside diphosphate kinase
• Formate dehydrogenase
• NAD synthase
• Nuclear transcription factor Y
• Methanol dehydrogenase
• Matriptase
• Manganese peroxidase
• Mandelate racemase
• MEP cytidylyltransferase
• Mandelate dehydrogenase
• Malate synthase
• Macrophage inhibitory factor
• Homocitrate synthase
• Hemagglutinin-esterase
• Guanylate kinase
• Granzyme
• Glycosylasparaginase
• Glutaryl-CoA dehydrogenase
• Glutaminase
• Glutamate racemase
• Glucuronidase
• Glucose-1-phosphate thymidylyltransferase
• Geranylgeranyl transferase
• Galactose mutarotase
• Ficolin
• Phosphoinositide phosphatase
• Ferredoxin thioredoxin reductase
• PcrH
• Exportin
• Exoenzyme
• Epoxide hydrolase
• Elongation factor
• DNA damage-binding protein
• DNA adenine methylase
• Glucose 6-phosphate dehydrogenase
• Diphthine synthase
• Cytochrome f
• Cullin
• Cruzain
• Complement C3
• Formyl-CoA transferase
• Ferric hydroxamate uptake receptor
• Enoylpyruvate transferase
• Enoyl-CoA hydratase
• Cholesterol oxidase
• Ceruloplasmin
• Calpain
• DXP reductoisomerase
• Diphtheria toxin
• Diphtheria toxin repressor
• Diguanylate cyclase
• Dehydroquinase
• Dehaloperoxidase
• Death-associated protein kinase
• D-aminoacylase
• Cytochrome c peroxidase
• Cytochrome b5
• Cyclohydrolase
• Cocaine esterase
• CotA laccase
• Colicin I receptor
• Choline O-acetyltransferase
• Choline kinase
• 5'-deoxy-5'-methylthioadenosine phosphorylase
• CD4
• Casein kinase
• Nitrile hydratase
• UDP-3-O-acyl-N-acetylglucosamine deacetylase
• Chitinase-3-like protein
• Insulin-like growth factor receptor
• Ribose-binding protein
• Nitrite reductase
• DNA methyltransferase
• Pre-mRNA-splicing factor
• Carboxylesterase
• Ankyrin
• Acetylcholinesterase with DFP
• IFG/DG-Cerezyme
• C-terminal portion of human eIF4GI
• Death Associated Protein 5
• Acetylcholinesterase complexed with N-9-(1',2',3',4'-tetrahydroacridinyl)-1,8-diaminooctane
• Torpedo californica acetylcholinesterase with alkylene-linked tacrine dimer (5 carbon linker)
• Thioredoxin Glutathione Reductase