User:Alexander Berchansky

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (13:37, 20 July 2021) (edit) (undo)
 
(163 intermediate revisions not shown.)
Line 4: Line 4:
{{Clear}}
{{Clear}}
-
Interesting pages:
+
'''My interesting pages:'''
*[[Acetylcholinesterase]]
*[[Acetylcholinesterase]]
*[[AChE inhibitors and substrates]]
*[[AChE inhibitors and substrates]]
*[[Mutations in BRCA1/BARD1 RING-domain heterodimer]]
*[[Mutations in BRCA1/BARD1 RING-domain heterodimer]]
*[[Mutations in Brca1 BRCT Domains]]
*[[Mutations in Brca1 BRCT Domains]]
 +
*[[Lactate Dehydrogenase]]
 +
*[[Human Acetylcholinesterase]]
*[[Journal:Proteins:2|Missense Mutations in Phenylalanine Hydroxylase]]
*[[Journal:Proteins:2|Missense Mutations in Phenylalanine Hydroxylase]]
-
*[[Journal:JBIC:8|A hydrogen-bonding network formed by the B10-E7-E11 residues of a truncated hemoglobin from Tetrahymena pyriformis is critical for stability of bound oxygen and nitric oxide detoxification]]
+
*[[Ferredoxin]]
*[[Phosphofructokinase (PFK)]]
*[[Phosphofructokinase (PFK)]]
*[[Alcohol dehydrogenase]]
*[[Alcohol dehydrogenase]]
*[[Beta-glucosidase]]
*[[Beta-glucosidase]]
-
*[[Journal:Acta Cryst D:S0907444911047251|Flexibility of the flap in the active site of BACE1 as revealed by crystal structures and molecular dynamics simulations]]
+
*[[Aricept Complexed with Acetylcholinesterase (Hebrew)]]
-
*[[Journal:Acta Cryst D:S2059798318000050|A DNA structural alphabet provides new insight into DNA flexibility]]
+
*[[Aricept Complexed with Acetylcholinesterase (Russian)]]
-
*[[Journal:Acta Cryst F:S1744309112050270|Crystal structure of ADL1, a plant-specific homologue of the universal diaminopimelate amino transferase enzyme of lysine biosynthesis]]
+
*[[Prion]]
-
*[[Journal:Acta Cryst F:S1744309112003326|Structure of recombinant human carboxylesterase 1 isolated from whole cabbage looper larvae]]
+
*[[Viral capsids]]
 +
*[[Journal:Acta Cryst D:S2059798320011869|Lattice-translocation defects in some specific crystals of the catalytic head domain of influenza neuraminidase]], Linghui Li, Shuliu Dai, George F. Gao and Jiawei Wang [http://dx.doi.org/10.1107/S2059798320011869 http://dx.doi.org/10.1107/S2059798320011869]
 +
*[[Proteins from Mycobacterium tuberculosis]]
 +
*[[Treatment of Tuberculosis]]
 +
*[[Iron–sulfur proteins]]
 +
*[[Hemeproteins]]
 +
*[[Neurotransmitters]]
 +
*[[Growth factors]]
 +
*[[Receptor]]
 +
*[[Hormones and their receptors]]
 +
 
 +
'''CRISPR-Cas (under development):'''
 +
*[[CRISPR-Cas|CRISPR-Cas Part I]]
 +
*[[CRISPR-Cas Part II]]
 +
*[[CRISPR-Cas9]]
 +
 
 +
'''Classification according to the Wikipedia page CRISPR [https://en.wikipedia.org/wiki/CRISPR] with additions'''
 +
 
 +
'''CRISPR Class 1 uses a complex of multiple Cas proteins'''
 +
 
 +
CRISPR type I (Cas3)
 +
 
 +
CRISPR type I-A (Cascade) - see [[CRISPR subtype I-A]]
 +
 
 +
CRISPR type I-B (Cascade) - see [[CRISPR subtype I-B]]
 +
 
 +
CRISPR type I-C (Cascade) - see [[CRISPR subtype I-C]]
 +
 
 +
CRISPR type I-D (Cas10d)
 +
 
 +
CRISPR type I-E (Cascade) - see [[CRISPR type I-E (Cascade)|CRISPR subtype I-E]]
 +
 
 +
CRISPR type I-F (Csy1, Csy2, Csy3) - see [[CRISPR subtype I-F]]
 +
 
 +
CRISPR type I-U (GSU0054)
 +
 
 +
CRISPR type III (Cas10)
 +
 
 +
CRISPR type III-A (Csm complex) - see [[CRISPR subtype III-A (Csm complex)]]
 +
 
 +
CRISPR type III-B (Cmr complex)
 +
 
 +
CRISPR type III-C (Cas10 or Csx11)
 +
 
 +
CRISPR type III-D (Csx10)
 +
 
 +
CRISPR type Orphan
 +
 
 +
CRISPR type IV (Csf1)
 +
 
 +
CRISPR type IV-A
 +
 
 +
CRISPR type IV-B
 +
 
 +
'''CRISPR Class 2 uses a single large Cas protein'''
 +
 
 +
CRISPR type II-A - see [[CRISPR-Cas9]]
 +
 
 +
CRISPR type II-B (Cas4)
 +
 
 +
CRISPR type II-C
 +
 
 +
CRISPR type V (Cpf1, C2c1, C2c3) - see [[CRISPR type V]]
 +
 
 +
CRISPR type VI (Cas13a (previously known as C2c2), Cas13b, Cas13c, Cas13d) - see [[CRISPR type VI]]
 +
 
 +
*[[Journal:Protein Science:3|''Torpedo californica'' acetylcholinesterase is stabilized by binding of a divalent metal ion to a novel and versatile 4D motif]]
 +
*[[Journal:IUCrJ:S2052252521005340|X-ray crystallography studies of RoAb13 bound to PIYDIN, a part of the CCR5 N-terminal domain]]
 +
*[[Journal:Acta Cryst F:S2053230X20016015|Using Yeast Surface Display to Engineer a Soluble and Crystallizable Construct of HPK1]]
 +
*[[Journal:Acta Cryst D:S2059798320015004|The substrate binding in the bile acid transporter ASBT<sub>Yf</sub> of ''Yersinia frederiksenii'']]
 +
*[[Journal:Acta Cryst D:S205979832001517X|An engineered disulfide bridge traps and validates an outward-facing conformation in a bile acid transporter]]
 +
*[[Journal:Acta Cryst D:S2059798321003922|Structure of the human factor VIIa/soluble tissue factor with calcium, magnesium and rubidium]]
*[[Journal:Angew Chem Int Ed:1|Fine tuning of chlorophyll spectra by protein-induced ring deformation]]
*[[Journal:Angew Chem Int Ed:1|Fine tuning of chlorophyll spectra by protein-induced ring deformation]]
-
*[[Xanthine dehydrogenase]]
+
*[[Journal:JBIC:8|A hydrogen-bonding network formed by the B10-E7-E11 residues of a truncated hemoglobin from Tetrahymena pyriformis is critical for stability of bound oxygen and nitric oxide detoxification]]
 +
*[[Journal:JBIC:12|ISC-like [2Fe-2S] ferredoxin (FdxB) dimer from ''Pseudomonas putida'' JCM 20004: Structural and electron nuclear double resonance characterization]]
*[[Journal:JBIC:13|{{nowrap|N-Butylisocyanide Oxidation}} at the {{nowrap|&#91;NiFe<sub>4</sub>S<sub>4</sub>OH<sub>x</sub>&#93;-cluster}} of CO Dehydrogenase]]
*[[Journal:JBIC:13|{{nowrap|N-Butylisocyanide Oxidation}} at the {{nowrap|&#91;NiFe<sub>4</sub>S<sub>4</sub>OH<sub>x</sub>&#93;-cluster}} of CO Dehydrogenase]]
*[[Journal:JBIC:14|Multifaceted SlyD from ''Helicobacter pylori'': implication in [NiFe] hydrogenase maturation]]
*[[Journal:JBIC:14|Multifaceted SlyD from ''Helicobacter pylori'': implication in [NiFe] hydrogenase maturation]]
 +
*[[Journal:Acta Cryst D:S2059798320014540|Statistically correcting dynamical electron scattering improves refinement of protein nanocrystals, including charge refinement of coordinated metals]]
*[[Journal:JBIC:15|Potent Inhibition of Dinuclear Zinc(II) Peptidase, an Aminopeptidase from Aeromonas proteolytica, by 8-Quinolinol Derivatives: Inhibitor Design Based on Zn2+ Fluorophores, Kinetic, and X-ray Crystallographic Study]]
*[[Journal:JBIC:15|Potent Inhibition of Dinuclear Zinc(II) Peptidase, an Aminopeptidase from Aeromonas proteolytica, by 8-Quinolinol Derivatives: Inhibitor Design Based on Zn2+ Fluorophores, Kinetic, and X-ray Crystallographic Study]]
*[[Journal:JBIC:16|Laue Crystal Structure of ''Shewanella oneidensis'' Cytochrome c Nitrite Reductase from a High-yield Expression System]]
*[[Journal:JBIC:16|Laue Crystal Structure of ''Shewanella oneidensis'' Cytochrome c Nitrite Reductase from a High-yield Expression System]]
Line 45: Line 120:
*[[Journal:JBIC:7|Structural and kinetic studies of imidazole binding to two members of the cytochrome c6 family reveal an important role for a conserved heme pocket residue]]
*[[Journal:JBIC:7|Structural and kinetic studies of imidazole binding to two members of the cytochrome c6 family reveal an important role for a conserved heme pocket residue]]
*[[Journal:JBIC:9|Protein and metal cluster structure of the wheat metallothionein domain &gamma;-Ec-1. The second part of the puzzle.]]
*[[Journal:JBIC:9|Protein and metal cluster structure of the wheat metallothionein domain &gamma;-Ec-1. The second part of the puzzle.]]
-
*[[Ferredoxin]]
 
*[[Journal:JBIC:11|{{nowrap|A Cryo-Crystallographic}} Time Course for Peroxide Reduction by Rubrerythrin from ''Pyrococcus furiosus'']]
*[[Journal:JBIC:11|{{nowrap|A Cryo-Crystallographic}} Time Course for Peroxide Reduction by Rubrerythrin from ''Pyrococcus furiosus'']]
*[[Journal:JMB:1|Cyt1Aa Toxin: High Resolution Structure Reveals Implications for its Membrane-Perforating Function]]
*[[Journal:JMB:1|Cyt1Aa Toxin: High Resolution Structure Reveals Implications for its Membrane-Perforating Function]]
Line 88: Line 162:
*[[Journal:JBSD:40|Traditional Chinese medicine application in HIV: An ''in silico'' study]]
*[[Journal:JBSD:40|Traditional Chinese medicine application in HIV: An ''in silico'' study]]
*[[Journal:JBSD:41|Molecular Mechanism of HIV-1 gp120 Mutations That Reduce CD4 Binding Affinity]]
*[[Journal:JBSD:41|Molecular Mechanism of HIV-1 gp120 Mutations That Reduce CD4 Binding Affinity]]
 +
*[[Book:Structural Proteomics and its Impact on the Life Sciences:6]]‎
 +
*[[Journal:Acta Cryst D:S0907444911047251|Flexibility of the flap in the active site of BACE1 as revealed by crystal structures and molecular dynamics simulations]]
 +
*[[Journal:Acta Cryst D:S2059798318000050|A DNA structural alphabet provides new insight into DNA flexibility]]
 +
*[[Journal:Acta Cryst D:S2059798319000676|Crystal structures of pyrrolidone-carboxylate peptidase I from ''Deinococcus radiodurans'' reveal the mechanism of L-pyroglutamate recognition]]
 +
*[[Journal:Acta Cryst D:S2059798318014900|Structure of the AmyC GH13 alpha-amylase from Alicyclobacillus sp, reveals accommodation of starch branching points in the alpha-amylase family]]
 +
*[[Journal:Acta Cryst D:S2059798318017047|The crystal structure of the N-acetylglucosamine 2-epimerase from Nostoc sp. KVJ10 reveals the true dimer]]
 +
*[[Journal:Acta Cryst D:S2059798318015322|Structure of ISG15 from the bat species Myotis davidii and the impact of interdomain ISG15 interactions on viral protein engagement]]
 +
*[[Journal:Acta Cryst D:S2059798319000214|In-house high energy remote SAD-phasing using the magic triangle: how to tackle the P1 low symmetry using multiple orientations on the same human IBA57 crystal to increase multiplicity]]
 +
*[[Journal:Acta Cryst D:S2059798319002912|Crystal structure of the pseudoenzyme PDX1.2 in complex with its cognate enzyme PDX1.3]]
 +
*[[Journal:Acta Cryst D:S2059798319007113|Crystal Structure Determination of ''Pseudomonas stutzeri'' A1501 endoglucanase Cel5A]]
 +
*[[Journal:Acta Cryst D:S2059798319006995|Structural insight into a matured humanized monoclonal antibody HuA21 against HER2-overexpressing cancer cells]]
 +
*[[Journal:Acta Cryst D:S2059798319002304|The third structural switch in the molecule of archaeal translation initiation factor 2 and its possible role in initiation of GTP hydrolysis and removal of aIF2 from the ribosome]]
 +
*[[Journal:Acta Cryst D:S2059798319004169|Structural and functional insights into phosphomannose isomerase]]
 +
*[[Journal:Acta Cryst F:S2053230X18016217|The structure of ''Mycobacterium tuberculosis'' HtrA reveals an auto-regulatory mechanism]]
 +
*[[Journal:Acta Cryst F:S2053230X18014814|Crystal structure and kinetic analyses of a hexameric form of (S)-3-hydroxybutyryl-CoA dehydrogenase from Clostridium acetobutylicum]]
 +
*[[Journal:Acta Cryst F:S2053230X19000815|Crystal structure of Type VI immunity protein Tdi1 (Atu4351) from Agrobacterium tumefaciens]]
 +
*[[Journal:Acta Cryst F:S2053230X19004151|Phasing with calcium at home]]
 +
*[[Journal:Acta Cryst F:S2053230X19001213|Substrate analogue complex structure of ''Mycobacterium tuberculosis'' decaprenyl diphosphate synthase]]
 +
*[[Journal:Acta Cryst F:S2053230X19004618|Novel T9 loop interaction of Filamenting Temperature-sensitive mutant Z from ''Mycobacterium tuberculosis'']]
 +
*[[Journal:Acta Cryst F:S1744309112050270|Crystal structure of ADL1, a plant-specific homologue of the universal diaminopimelate amino transferase enzyme of lysine biosynthesis]]
 +
*[[Journal:Acta Cryst F:S2053230X19002863|Functional and structural characterization of IdnL7, an adenylation enzyme involved in incednine biosynthesis]]
 +
*[[Journal:Acta Cryst F:S2053230X19004424|Structure of the Ebola virus nucleoprotein - RNA complex]]
 +
*[[Journal:Acta Cryst F:S1744309112003326|Structure of recombinant human carboxylesterase 1 isolated from whole cabbage looper larvae]]
 +
*[[Journal:Acta Cryst F:S2053230X18018083|An assessment of three human methylenetetrahydrofolate dehydrogenase/cyclohydrolase ligand complexes following further refinement]]
 +
*[[Journal:Acta Cryst F:S2053230X19002693|Crystal structure of phosphoribulokinase from ''Synechococcus sp.'' strain PCC 6301]]
 +
*[[Journal:Acta Cryst F:S1744309112003326|Structure of recombinant human carboxylesterase 1 isolated from whole cabbage looper larvae]]
 +
*[[Journal:Acta Cryst F:S2053230X19007192|Crystal Structure of Flavin Dependent Thymidylate Synthase, Thy1, from ''Thermus thermophilus'' having an Extra C Terminal Domain]]
 +
*[[Journal:BMC:3|Identification of novel isocytosine derivatives as xanthine oxidase inhibitors from a set of virtual screening hits]]
 +
*[[Journal:FEBS Open Bio:2|Structural evidence for Arabidopsis glutathione transferase AtGSTF2 functioning as a transporter of small organic ligands]]
 +
*[[Journal:IUCrJ:S2052252519002926|Determination of the Molecular Basis for Coprogen Import by Gram Negative Bacteria]]
 +
*[[Journal:IUCrJ:S2052252519001568|Structure of mammalian plasma fetuin-B and its mechanism of selective metallopeptidase inhibition]]
 +
*[[Journal:IUCrJ:S2052252518018274|A cytosine modification mechanism revealed by the ternary complex structure of deoxycytidylate hydroxymethylase from bacteriophage T4 with its cofactor and substrate]]
 +
*[[Journal:IUCrJ:S2052252519005372|The structural characterisation of a glucosylglycerate hydrolase provides insights into the molecular mechanism of mycobacterial recovery from nitrogen starvation]]
 +
*[[Journal:IUCrJ:S2052252519005761|Room-temperature photo-induced martensitic transformation in a protein crystal]]
 +
*[[SUMO]]
 +
*[[EPSP synthase]]
 +
*[[AMP-activated protein kinase]]
 +
*[[Xanthine dehydrogenase]]
 +
*[[Nicotinic Acetylcholine Receptor]]
*[[Cytochrome c]]
*[[Cytochrome c]]
*[[Methotrexate]]
*[[Methotrexate]]
 +
*[[Kemp elimination catalyst]]
*[[Urease]]
*[[Urease]]
*[[Phosphoglycerate Kinase]]
*[[Phosphoglycerate Kinase]]
 +
*[[Plant-derived glucocerebrosidase]]
*[[NADH quinone oxidoreductase (NQO1) with inhibitor dicoumarol]]
*[[NADH quinone oxidoreductase (NQO1) with inhibitor dicoumarol]]
 +
*[[Matrix metalloproteinase]]
 +
*[[Amino acid oxidase]]
 +
*[[Mutant immunity protein 9 (variant R12-13)]]
 +
*[[Acetylcholine binding protein]]
 +
*[[Hydroxylase]]
 +
*[[Actin]]
 +
*[[Torpedo Californica Acetylcholinesterase in complex with an (R)-Tacrine-(10)-Hupyridone inhibitor]]
 +
*[[Dronpa]]
 +
*[[Major histocompatibility complex]]
 +
*[[Mutant immunity protein 9 (variant R12-2)]]
 +
*[[Butyrylcholinesterase]]
 +
*[[Human acid-beta-glucosidase covalently bound to conduritol B epoxide]]
 +
*[[Avidin]]
 +
*[[Proteasome]]
 +
*[[FK506 binding protein]]
 +
*[[Insecticidal delta-endotoxin Cyt2Ba from Bacillus thuringiensis]]
 +
*[[Ubiquitin protein ligase]]
 +
*[[Catalase]]
 +
*[[Albumin]]
 +
*[[Aminopeptidase]]
 +
*[[Staphylococcal nuclease]]
 +
*[[Virus protease]]
 +
*[[Asparaginase]]
 +
*[[NAC transcription factor]]
 +
*[[Kemp eliminase]]
 +
*[[NADPH-Cytochrome P450 Reductase]]
 +
*[[Prolyl hydroxylase domain]]
 +
*[[Neuraminidase]]
 +
*[[Carbonic anhydrase]]
 +
*[[Carboxypeptidase]]
 +
*[[ABC transporter]]
 +
*[[Ubiquitin]]
 +
*[[Cytochrome P450]]
 +
*[[TEM1-beta-Lactamase/beta-lactamase Inhibitor Protein (BLIP)]]
 +
*[[Acid beta-glucosidase with N-butyl-deoxynojirimycin]]
 +
*[[Treatment of Gaucher disease]]
 +
*[[Acyl carrier protein synthase]]
 +
*[[Chimeras of alcohol dehydrogenases]]
 +
*[[Dihydrodipicolinate synthase]]
 +
*[[Directed evolution]]
 +
*[[Colicin Immunity Protein]]
 +
*[[Human FKBP52]]
 +
*[[Opioid receptor]]
 +
*[[Acetylcholine]]
 +
*[[Heat Shock Proteins]]
 +
*[[Dioxygenase]]
 +
*[[Flavodoxin]]
 +
*[[Phospholipase A2]]
 +
*[[Tyrosine kinase]]
 +
*[[Cellobiohydrolase]]
 +
*[[Acid phosphatase]]
 +
*[[Neuroglobin]]
 +
*[[Hirudin]]
 +
*[[GTP-binding protein]]
 +
*[[Aldehyde dehydrogenase]]
 +
*[[Delta-endotoxin]]
 +
*[[Beta-lactamase]]
 +
*[[Estrogen receptor]]
 +
*[[DNA-binding protein VirE2 from Agrobacterium tumefaciens complexed with chaperone VirE1]]
 +
*[[Alkaline phosphatase]]
 +
*[[Cathepsin]]
 +
*[[Prolyl Endopeptidase]]
 +
*[[Forkhead box protein]]
 +
*[[Subtilisin]]
 +
*[[Hyaluronidase]]
 +
*[[Lysine-specific histone demethylase]]
 +
*[[Glycolate oxidase]]
 +
*[[Chaperonin]]
 +
*[[Nucleoprotein]]
 +
*[[Transcriptional activator]]
 +
*[[Chitinase]]
 +
*[[Cluster of Differentiation CD38]]
 +
*[[Tubulin]]
 +
*[[SAM-dependent methyltransferase]]
 +
*[[Lignin peroxidase]]
 +
*[[Gyrase]]
 +
*[[Methylesterase]]
 +
*[[CAMP-dependent protein kinase]]
 +
*[[Plasminogen]]
 +
*[[Choline Oxidase]]
 +
*[[Thioesterase]]
 +
*[[Dopamine receptor]]
 +
*[[Mitogen-activated protein kinase kinase]]
 +
*[[Kinesin]]
 +
*[[Gelsolin]]
 +
*[[DNA glycosylase]]
 +
*[[Mitogen-activated protein kinase]]
 +
*[[Factor VIII]]
 +
*[[BtuB]]
 +
*[[BLUF domain protein]]
 +
*[[Botulinum neurotoxin]]
 +
*[[Blue copper oxidase CueO]]
 +
*[[Beta-phosphoglucomutase]]
 +
*[[Beta-ketoacyl-ACP reductase]]
 +
*[[Beta-adrenergic receptor kinase]]
 +
*[[Barnase]]
 +
*[[Bacteriorhodopsin]]
 +
*[[BA42]]
 +
*[[Gramicidin]]
 +
*[[Horseradish peroxidase]]
 +
*[[Azurin]]
 +
*[[Avirulence protein]]
 +
*[[Autophagy-related protein]]
 +
*[[ATP-citrate synthase]]
 +
*[[Atlastin]]
 +
*[[Catabolite gene activator protein]]
 +
*[[Cytochrome bc1 complex]]
 +
*[[Lactoferrin]]
 +
*[[Glycosyltransferase]]
 +
*[[Factor inhibiting HIF]]
 +
*[[Ephrin receptor]]
 +
*[[Aspartoacylase]]
 +
*[[Aspartate carbamoyltransferase]]
 +
*[[Proliferating Cell Nuclear Antigen]]
 +
*[[Aspartate-semialdehyde dehydrogenase]]
 +
*[[Ascorbate peroxidase]]
 +
*[[Aromatic amine dehydrogenase]]
 +
*[[Arginine kinase]]
 +
*[[Antigen 85]]
 +
*[[Anti-sigma factor antagonist]]
 +
*[[Anthrax protective antigen]]
 +
*[[Anthrax edema factor]]
 +
*[[Annexin]]
 +
*[[Aminotransferase]]
 +
*[[Alpha-tubulin N-acetyltransferase]]
 +
*[[Alpha-lytic protease]]
 +
*[[Aldose Reductase]]
 +
*[[Alanine racemase]]
 +
*[[Agglutinin]]
 +
*[[ADP-ribose pyrophosphatase]]
 +
*[[Poly (ADP-ribose) polymerase]]
 +
*[[Adenylosuccinate lyase]]
 +
*[[Adenosine kinase]]
 +
*[[Adenosine deaminase]]
 +
*[[Adenosine A2A receptor]]
 +
*[[Adaptin]]
 +
*[[Acylaminoacyl peptidase]]
 +
*[[Acyl carrier protein]]
 +
*[[Acyl-CoA dehydrogenase]]
 +
*[[Acetylxylan esterase]]
 +
*[[Acetyl-CoA carboxylase]]
 +
*[[Acetyl-CoA synthetase]]
 +
*[[Acetyl-CoA synthase]]
 +
*[[Cytochrome c oxidase]]
 +
*[[Concanavalin A]]
 +
*[[Neurexin]]
 +
*[[Histone deacetylase]]
 +
*[[Purine repressor]]
 +
*[[Protein phosphatase]]
 +
*[[Glutamate synthase]]
 +
*[[4-hydroxy-3-methylbut-2-enyl diphosphate reductase]]
 +
*[[6-aminohexanoate-dimer hydrolase]]
 +
*[[6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase]]
 +
*[[7,8-dihydro-8-oxoguanine triphosphatase]]
 +
*[[Cell division protein]]
 +
*[[Carbon monoxide dehydrogenase]]
 +
*[[CXC chemokine receptor]]
 +
*[[Cyclin-dependent kinase]]
 +
*[[12-oxophytodienoate reductase]]
 +
*[[Enoyl-Acyl-Carrier Protein Reductase]]
 +
*[[Dihydrolipoamide acetyltransferase]]
 +
*[[Alpha-glucosidase]]
 +
*[[Apoptotic protease-activating factor]]
 +
*[[Arginase]]
 +
*[[Adhesin]]
 +
*[[Arabinanase]]
 +
*[[Gp120]]
 +
*[[GMP synthase]]
 +
*[[Leukotriene A4 Hydrolase]]
 +
*[[Biotin Protein Ligase]]
 +
*[[Androgen receptor]]
 +
*[[Glutamate dehydrogenase]]
 +
*[[14-3-3 protein]]
 +
*[[Fibrin]]
 +
*[[3C protease]]
 +
*[[GTPase KRas]]
 +
*[[6-phosphogluconate dehydrogenase]]
 +
*[[Mineralocorticoid receptor]]
 +
*[[Thyroid hormone receptor]]
 +
*[[Progesterone receptor]]
 +
*[[Serpin]]
 +
*[[Leucine transporter]]
 +
*[[Microtubule-associated protein]]
 +
*[[Ectonucleotide pyrophosphatase/phosphodiesterase]]
 +
*[[Ribosome biogenesis protein]]
 +
*[[Liver X receptor]]
 +
*[[Nitrophorin]]
 +
*[[VprBP]]
 +
*[[Growth factor receptor-bound protein]]
 +
*[[CREB-binding protein]]
 +
*[[Kdo-8-phosphate synthase]]
 +
*[[Signal recognition particle receptor]]
 +
*[[Liver receptor homolog-1]]
 +
*[[Orexin and Orexin receptor]]
 +
*[[Spindlin]]
 +
*[[Prostaglandin E synthase]]
 +
*[[Terminase]]
 +
*[[Mandelate racemase/muconate lactonizing enzyme]]
 +
*[[GABA(A) receptor-associated protein]]
 +
*[[IspG]]
 +
*[[Haloperoxidase]]
 +
*[[Cytochrome P450 hydroxylase]]
 +
*[[Period circadian protein]]
 +
*[[Proteinase]]
 +
*[[Sialyltransferase]]
 +
*[[Neprilysin]]
 +
*[[Cholesterol esterase]]
 +
*[[Chloramphenicol acetyltransferase]]
 +
*[[Thiolase]]
 +
*[[CCA-adding enzyme]]
 +
*[[Glucose-fructose oxidoreductase]]
 +
*[[Tripeptidyl peptidase]]
 +
*[[Tryptophan synthase]]
 +
*[[Fatty acid synthase]]
 +
*[[Glucosamine 6-phosphate synthase]]
 +
*[[Rho GTPase activating protein]]
 +
*[[Ornithine decarboxylase]]
 +
*[[Prostaglandin D synthase]]
 +
*[[Prestin]]
 +
*[[Polyamine oxidase]]
 +
*[[Phosphotransferase]]
 +
*[[Phosphodiesterase]]
 +
*[[Plexin]]
 +
*[[Plasminogen activator]]
 +
*[[Plasmid segregation protein ParM]]
 +
*[[Phospholipase C]]
 +
*[[Phosphoenolpyruvate carboxylase]]
 +
*[[Peptide N-glycanase]]
 +
*[[Penicillopepsin]]
 +
*[[Penicillin acylase]]
 +
*[[PCSK9]]
 +
*[[Galactose-binding lectin]]
 +
*[[Paired box protein]]
 +
*[[D-xylose isomerase]]
 +
*[[Adrenodoxin reductase]]
 +
*[[Methylamine dehydrogenase]]
 +
*[[Oligopeptide-binding protein]]
 +
*[[Met repressor]]
 +
*[[Nuclear receptor coactivator]]
 +
*[[Neuropilin]]
 +
*[[NADH peroxidase]]
 +
*[[Deoxyuridine 5'-triphosphate nucleotidohydrolase]]
 +
*[[LDL receptor]]
 +
*[[P63]]
 +
*[[Galactose oxidase]]
 +
*[[Leukotriene B4 hydroxydehydrogenase]]
 +
*[[Leukocyte immunoglobulin-like receptor]]
 +
*[[Alpha-lactalbumin]]
 +
*[[3-phosphoinositide-dependent protein kinase 1]]
 +
*[[2-isopropylmalate synthase]]
 +
*[[Kelch-like protein]]
 +
*[[Lactoperoxidase]]
 +
*[[Mur ligase]]
 +
*[[Calcineurin]]
 +
*[[S100 protein]]
 +
*[[Ecotin]]
 +
*[[Leukotriene C4 synthase]]
 +
*[[Jumonji domain-containing protein]]
 +
*[[Monooxygenase]]
 +
*[[Vanillyl-alcohol oxidase]]
 +
*[[Isopropylmalate dehydrogenase]]
 +
*[[Tumor necrosis factor]]
 +
*[[Tumor necrosis factor receptor]]
 +
*[[Mannosidase]]
 +
*[[Transthyretin]]
 +
*[[Transport inhibitor response 1]]
 +
*[[Transducin]]
 +
*[[Nitrate reductase]]
 +
*[[Nitroreductase]]
 +
*[[Dihydroorotate dehydrogenase]]
 +
*[[L-rhamnose isomerase]]
 +
*[[TRAIL]]
 +
*[[Estrogen-related receptor]]
 +
*[[Inosine monophosphate dehydrogenase]]
 +
*[[Survivin]]
 +
*[[UDP-N-acetylglucosamine acyltransferase]]
 +
*[[Haptoglobin receptor]]
 +
*[[D-alanine-D-alanine ligase]]
 +
*[[Glutaminyl cyclase]]
 +
*[[Severin]]
 +
*[[Carnitine palmitoyltransferase]]
 +
*[[Isoaspartyl dipeptidase]]
 +
*[[Thiaminase]]
 +
*[[Acetylcholinesterase with OTMA]]
 +
*[[D275P mutant of alcohol dehydrogenase from protozoa Entamoeba histolytica]]
 +
*[[Ferripyoverdine receptor]]
 +
*[[Fatty acid-binding protein]]
 +
*[[Rho-associated protein kinase]]
 +
*[[Endonuclease]]
 +
*[[Collagenase (non-MMP)]]
 +
*[[Epoxidase]]
 +
*[[Ferrochelatase]]
 +
*[[Elastase]]
 +
*[[Tyrosinase]]
 +
*[[N-acetylornithine carbamoyltransferase]]
 +
*[[Ornithine carbamoyltransferase]]
 +
*[[Pantothenate kinase]]
 +
*[[Pantothenate synthetase]]
 +
*[[Parvalbumin]]
 +
*[[Cephalosporin acylase]]
 +
*[[Dipeptidyl peptidase]]
 +
*[[Farnesyltransferase]]
 +
*[[Farnesyl diphosphate synthase]]
 +
*[[Arginine repressor]]
 +
*[[Transferrin]]
 +
*[[Transketolase]]
 +
*[[Dihydropteroate synthase]]
 +
*[[Trichodiene synthase]]
 +
*[[DAHP synthase]]
 +
*[[Trehalulose synthase]]
 +
*[[TRNA-guanine transglycosylase]]
 +
*[[Cyclophilin]]
 +
*[[Cutinase]]
 +
*[[Trypanothione reductase]]
 +
*[[Trypsin inhibitor]]
 +
*[[Tryptase]]
 +
*[[Tubulin tyrosine ligase]]
 +
*[[Transaldolase]]
 +
*[[Urokinase]]
 +
*[[Undecaprenyl pyrophosphate synthase]]
 +
*[[UDP-galactose 4-epimerase]]
 +
*[[Uridine 5'-monophosphate synthase]]
 +
*[[Arsenate reductase]]
 +
*[[Rac]]
 +
*[[Rho GTPase]]
 +
*[[Carbamoyl phosphate synthetase]]
 +
*[[Dedicator of cytokinesis protein]]
 +
*[[Phosphoribosylaminoimidazole carboxylase]]
 +
*[[Retinoid isomerohydrolase]]
 +
*[[Calcium uptake protein 1]]
 +
*[[Abscisic acid receptor]]
 +
*[[Apoptosis-inducing factor]]
 +
*[[Nucleolin]]
 +
*[[Aldo-keto reductase]]
 +
*[[SAICAR synthetase]]
 +
*[[Prolactin receptor]]
 +
*[[Siderocalin]]
 +
*[[Latrophilin]]
 +
*[[Folypolyglutamate synthase]]
 +
*[[WD repeat-containing protein]]
 +
*[[Xylosidase]]
 +
*[[Uridylate kinase]]
 +
*[[Penicillin-binding protein]]
 +
*[[Pentaerythritol tetranitrate reductase]]
 +
*[[Thymidine kinase]]
 +
*[[Thymidylate kinase]]
 +
*[[Tissue factor pathway inhibitor]]
 +
*[[Thioredoxin Reductase]]
 +
*[[Peptidyl-tRNA hydrolase]]
 +
*[[Peroxiredoxin]]
 +
*[[Phenylethanolamine N-methyltransferase]]
 +
*[[Tetracycline repressor protein]]
 +
*[[Phenylpyruvate decarboxylase]]
 +
*[[Succinate-semialdehyde dehydrogenase]]
 +
*[[Spermidine/spermine N-acetyltransferase]]
 +
*[[Sulfotransferase]]
 +
*[[Phosphomannomutase]]
 +
*[[Strictosidine Synthase]]
 +
*[[Phosphoenolpyruvate carboxykinase]]
 +
*[[Phosphoribosyltransferase]]
 +
*[[Phosphoserine aminotransferase]]
 +
*[[Phosphoserine phosphatase]]
 +
*[[Shikimate kinase]]
 +
*[[Shikimate dehydrogenase]]
 +
*[[Selectin]]
 +
*[[Selenocysteine synthase]]
 +
*[[Semaphorin]]
 +
*[[Serine palmitoyltransferase]]
 +
*[[SAM decarboxylase]]
 +
*[[SAM synthetase]]
 +
*[[S-adenosylhomocysteine hydrolase]]
 +
*[[Plasmepsin]]
 +
*[[RNA uridylyltransferase]]
 +
*[[Ribosomal protein S6 kinase]]
 +
*[[Poly(A) RNA polymerase protein Cid1]]
 +
*[[Ribonucleotide reductase]]
 +
*[[Phycocyanobilin:ferredoxin oxidoreductase]]
 +
*[[Poly (ADP-ribose) glycohydrolase]]
 +
*[[Rhomboid protease]]
 +
*[[Rhodopsin kinase]]
 +
*[[Retinol-binding protein]]
 +
*[[Polyneuridine Aldehyde Esterase]]
 +
*[[Retinoid X receptor]]
 +
*[[Porphobilinogen synthase]]
 +
*[[Retinoblastoma-binding protein]]
 +
*[[Pyruvate dehydrogenase kinase]]
 +
*[[Pyruvate-ferredoxin oxidoreductase]]
 +
*[[Pyrroline-5-carboxylate dehydrogenase]]
 +
*[[Purine nucleoside phosphorylase]]
 +
*[[Proline utilization A]]
 +
*[[Protein kinase C]]
 +
*[[Nucleoside diphosphate kinase]]
 +
*[[Formate dehydrogenase]]
 +
*[[NAD synthase]]
 +
*[[Nuclear transcription factor Y]]
 +
*[[Methanol dehydrogenase]]
 +
*[[Matriptase]]
 +
*[[Manganese peroxidase]]
 +
*[[Mandelate racemase]]
 +
*[[MEP cytidylyltransferase]]
 +
*[[Mandelate dehydrogenase]]
 +
*[[Malate synthase]]
 +
*[[Macrophage inhibitory factor]]
 +
*[[Homocitrate synthase]]
 +
*[[Hemagglutinin-esterase]]
 +
*[[Guanylate kinase]]
 +
*[[Granzyme]]
 +
*[[Glycosylasparaginase]]
 +
*[[Glutaryl-CoA dehydrogenase]]
 +
*[[Glutaminase]]
 +
*[[Glutamate racemase]]
 +
*[[Glucuronidase]]
 +
*[[Glucose-1-phosphate thymidylyltransferase]]
 +
*[[Geranylgeranyl transferase]]
 +
*[[Galactose mutarotase]]
 +
*[[Ficolin]]
 +
*[[Phosphoinositide phosphatase]]
 +
*[[Ferredoxin thioredoxin reductase]]
 +
*[[PcrH]]
 +
*[[Exportin]]
 +
*[[Exoenzyme]]
 +
*[[Epoxide hydrolase]]
 +
*[[Elongation factor]]
 +
*[[DNA damage-binding protein]]
 +
*[[DNA adenine methylase]]
 +
*[[Glucose 6-phosphate dehydrogenase]]
 +
*[[Diphthine synthase]]
 +
*[[Cytochrome f]]
 +
*[[Cullin]]
 +
*[[Cruzain]]
 +
*[[Complement C3]]
 +
*[[Formyl-CoA transferase]]
 +
*[[Ferric hydroxamate uptake receptor]]
 +
*[[Enoylpyruvate transferase]]
 +
*[[Enoyl-CoA hydratase]]
 +
*[[Cholesterol oxidase]]
 +
*[[Ceruloplasmin]]
 +
*[[Calpain]]
 +
*[[DXP reductoisomerase]]
 +
*[[Diphtheria toxin]]
 +
*[[Diphtheria toxin repressor]]
 +
*[[Diguanylate cyclase]]
 +
*[[Dehydroquinase]]
 +
*[[Dehaloperoxidase]]
 +
*[[Death-associated protein kinase]]
 +
*[[D-aminoacylase]]
 +
*[[Cytochrome c peroxidase]]
 +
*[[Cytochrome b5]]
 +
*[[Cyclohydrolase]]
 +
*[[Cocaine esterase]]
 +
*[[CotA laccase]]
 +
*[[Colicin I receptor]]
 +
*[[Choline O-acetyltransferase]]
 +
*[[Choline kinase]]
 +
*[[5'-deoxy-5'-methylthioadenosine phosphorylase]]
 +
*[[CD4]]
 +
*[[Casein kinase]]
 +
*[[Nitrile hydratase]]
 +
*[[UDP-3-O-acyl-N-acetylglucosamine deacetylase]]
 +
*[[Chitinase-3-like protein]]
 +
*[[Insulin-like growth factor receptor]]
 +
*[[Ribose-binding protein]]
 +
*[[Nitrite reductase]]
 +
*[[DNA methyltransferase]]
 +
*[[Pre-mRNA-splicing factor]]
 +
*[[Carboxylesterase]]
 +
*[[Ankyrin]]
 +
*[[Acetylcholinesterase with DFP]]
 +
*[[IFG/DG-Cerezyme]]
 +
*[[C-terminal portion of human eIF4GI]]
 +
*[[Death Associated Protein 5]]
 +
*[[Acetylcholinesterase complexed with N-9-(1',2',3',4'-tetrahydroacridinyl)-1,8-diaminooctane]]
 +
*[[Torpedo californica acetylcholinesterase with alkylene-linked tacrine dimer (5 carbon linker)]]
 +
*[[Thioredoxin Glutathione Reductase]]
 +
*[[Journal:PMC:1]]

Current revision

Dr. Alexander Berchansky, Ph.D., Israel Structural Proteomics Center, Weizmann Institute of Science

My interesting pages:

CRISPR-Cas (under development):

Classification according to the Wikipedia page CRISPR [1] with additions

CRISPR Class 1 uses a complex of multiple Cas proteins

CRISPR type I (Cas3)

CRISPR type I-A (Cascade) - see CRISPR subtype I-A

CRISPR type I-B (Cascade) - see CRISPR subtype I-B

CRISPR type I-C (Cascade) - see CRISPR subtype I-C

CRISPR type I-D (Cas10d)

CRISPR type I-E (Cascade) - see CRISPR subtype I-E

CRISPR type I-F (Csy1, Csy2, Csy3) - see CRISPR subtype I-F

CRISPR type I-U (GSU0054)

CRISPR type III (Cas10)

CRISPR type III-A (Csm complex) - see CRISPR subtype III-A (Csm complex)

CRISPR type III-B (Cmr complex)

CRISPR type III-C (Cas10 or Csx11)

CRISPR type III-D (Csx10)

CRISPR type Orphan

CRISPR type IV (Csf1)

CRISPR type IV-A

CRISPR type IV-B

CRISPR Class 2 uses a single large Cas protein

CRISPR type II-A - see CRISPR-Cas9

CRISPR type II-B (Cas4)

CRISPR type II-C

CRISPR type V (Cpf1, C2c1, C2c3) - see CRISPR type V

CRISPR type VI (Cas13a (previously known as C2c2), Cas13b, Cas13c, Cas13d) - see CRISPR type VI

Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky, Eran Hodis

Personal tools