User:Alexander Berchansky
From Proteopedia
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- | + | '''My interesting pages:''' | |
*[[Acetylcholinesterase]] | *[[Acetylcholinesterase]] | ||
*[[AChE inhibitors and substrates]] | *[[AChE inhibitors and substrates]] | ||
*[[Mutations in BRCA1/BARD1 RING-domain heterodimer]] | *[[Mutations in BRCA1/BARD1 RING-domain heterodimer]] | ||
*[[Mutations in Brca1 BRCT Domains]] | *[[Mutations in Brca1 BRCT Domains]] | ||
+ | *[[Lactate Dehydrogenase]] | ||
+ | *[[Human Acetylcholinesterase]] | ||
*[[Journal:Proteins:2|Missense Mutations in Phenylalanine Hydroxylase]] | *[[Journal:Proteins:2|Missense Mutations in Phenylalanine Hydroxylase]] | ||
- | *[[ | + | *[[Ferredoxin]] |
*[[Phosphofructokinase (PFK)]] | *[[Phosphofructokinase (PFK)]] | ||
*[[Alcohol dehydrogenase]] | *[[Alcohol dehydrogenase]] | ||
*[[Beta-glucosidase]] | *[[Beta-glucosidase]] | ||
- | *[[Journal:Acta Cryst D: | + | *[[Aricept Complexed with Acetylcholinesterase (Hebrew)]] |
- | *[[Journal: | + | *[[Aricept Complexed with Acetylcholinesterase (Russian)]] |
- | *[[Journal:Acta Cryst F: | + | *[[Prion]] |
- | *[[Journal:Acta Cryst | + | *[[Viral capsids]] |
+ | *[[Journal:Acta Cryst D:S2059798320011869|Lattice-translocation defects in some specific crystals of the catalytic head domain of influenza neuraminidase]], Linghui Li, Shuliu Dai, George F. Gao and Jiawei Wang [http://dx.doi.org/10.1107/S2059798320011869 http://dx.doi.org/10.1107/S2059798320011869] | ||
+ | *[[Proteins from Mycobacterium tuberculosis]] | ||
+ | *[[Treatment of Tuberculosis]] | ||
+ | *[[Iron–sulfur proteins]] | ||
+ | *[[Hemeproteins]] | ||
+ | *[[Neurotransmitters]] | ||
+ | *[[Growth factors]] | ||
+ | *[[Receptor]] | ||
+ | *[[Hormones and their receptors]] | ||
+ | |||
+ | '''CRISPR-Cas (under development):''' | ||
+ | *[[CRISPR-Cas|CRISPR-Cas Part I]] | ||
+ | *[[CRISPR-Cas Part II]] | ||
+ | *[[CRISPR-Cas9]] | ||
+ | |||
+ | '''Classification according to the Wikipedia page CRISPR [https://en.wikipedia.org/wiki/CRISPR] with additions''' | ||
+ | |||
+ | '''CRISPR Class 1 uses a complex of multiple Cas proteins''' | ||
+ | |||
+ | CRISPR type I (Cas3) | ||
+ | |||
+ | CRISPR type I-A (Cascade) - see [[CRISPR subtype I-A]] | ||
+ | |||
+ | CRISPR type I-B (Cascade) - see [[CRISPR subtype I-B]] | ||
+ | |||
+ | CRISPR type I-C (Cascade) - see [[CRISPR subtype I-C]] | ||
+ | |||
+ | CRISPR type I-D (Cas10d) | ||
+ | |||
+ | CRISPR type I-E (Cascade) - see [[CRISPR type I-E (Cascade)|CRISPR subtype I-E]] | ||
+ | |||
+ | CRISPR type I-F (Csy1, Csy2, Csy3) - see [[CRISPR subtype I-F]] | ||
+ | |||
+ | CRISPR type I-U (GSU0054) | ||
+ | |||
+ | CRISPR type III (Cas10) | ||
+ | |||
+ | CRISPR type III-A (Csm complex) - see [[CRISPR subtype III-A (Csm complex)]] | ||
+ | |||
+ | CRISPR type III-B (Cmr complex) | ||
+ | |||
+ | CRISPR type III-C (Cas10 or Csx11) | ||
+ | |||
+ | CRISPR type III-D (Csx10) | ||
+ | |||
+ | CRISPR type Orphan | ||
+ | |||
+ | CRISPR type IV (Csf1) | ||
+ | |||
+ | CRISPR type IV-A | ||
+ | |||
+ | CRISPR type IV-B | ||
+ | |||
+ | '''CRISPR Class 2 uses a single large Cas protein''' | ||
+ | |||
+ | CRISPR type II-A - see [[CRISPR-Cas9]] | ||
+ | |||
+ | CRISPR type II-B (Cas4) | ||
+ | |||
+ | CRISPR type II-C | ||
+ | |||
+ | CRISPR type V (Cpf1, C2c1, C2c3) - see [[CRISPR type V]] | ||
+ | |||
+ | CRISPR type VI (Cas13a (previously known as C2c2), Cas13b, Cas13c, Cas13d) - see [[CRISPR type VI]] | ||
+ | |||
+ | *[[Journal:Protein Science:3|''Torpedo californica'' acetylcholinesterase is stabilized by binding of a divalent metal ion to a novel and versatile 4D motif]] | ||
+ | *[[Journal:IUCrJ:S2052252521005340|X-ray crystallography studies of RoAb13 bound to PIYDIN, a part of the CCR5 N-terminal domain]] | ||
+ | *[[Journal:Acta Cryst F:S2053230X20016015|Using Yeast Surface Display to Engineer a Soluble and Crystallizable Construct of HPK1]] | ||
+ | *[[Journal:Acta Cryst D:S2059798320015004|The substrate binding in the bile acid transporter ASBT<sub>Yf</sub> of ''Yersinia frederiksenii'']] | ||
+ | *[[Journal:Acta Cryst D:S205979832001517X|An engineered disulfide bridge traps and validates an outward-facing conformation in a bile acid transporter]] | ||
+ | *[[Journal:Acta Cryst D:S2059798321003922|Structure of the human factor VIIa/soluble tissue factor with calcium, magnesium and rubidium]] | ||
*[[Journal:Angew Chem Int Ed:1|Fine tuning of chlorophyll spectra by protein-induced ring deformation]] | *[[Journal:Angew Chem Int Ed:1|Fine tuning of chlorophyll spectra by protein-induced ring deformation]] | ||
- | *[[ | + | *[[Journal:JBIC:8|A hydrogen-bonding network formed by the B10-E7-E11 residues of a truncated hemoglobin from Tetrahymena pyriformis is critical for stability of bound oxygen and nitric oxide detoxification]] |
+ | *[[Journal:JBIC:12|ISC-like [2Fe-2S] ferredoxin (FdxB) dimer from ''Pseudomonas putida'' JCM 20004: Structural and electron nuclear double resonance characterization]] | ||
*[[Journal:JBIC:13|{{nowrap|N-Butylisocyanide Oxidation}} at the {{nowrap|[NiFe<sub>4</sub>S<sub>4</sub>OH<sub>x</sub>]-cluster}} of CO Dehydrogenase]] | *[[Journal:JBIC:13|{{nowrap|N-Butylisocyanide Oxidation}} at the {{nowrap|[NiFe<sub>4</sub>S<sub>4</sub>OH<sub>x</sub>]-cluster}} of CO Dehydrogenase]] | ||
*[[Journal:JBIC:14|Multifaceted SlyD from ''Helicobacter pylori'': implication in [NiFe] hydrogenase maturation]] | *[[Journal:JBIC:14|Multifaceted SlyD from ''Helicobacter pylori'': implication in [NiFe] hydrogenase maturation]] | ||
+ | *[[Journal:Acta Cryst D:S2059798320014540|Statistically correcting dynamical electron scattering improves refinement of protein nanocrystals, including charge refinement of coordinated metals]] | ||
*[[Journal:JBIC:15|Potent Inhibition of Dinuclear Zinc(II) Peptidase, an Aminopeptidase from Aeromonas proteolytica, by 8-Quinolinol Derivatives: Inhibitor Design Based on Zn2+ Fluorophores, Kinetic, and X-ray Crystallographic Study]] | *[[Journal:JBIC:15|Potent Inhibition of Dinuclear Zinc(II) Peptidase, an Aminopeptidase from Aeromonas proteolytica, by 8-Quinolinol Derivatives: Inhibitor Design Based on Zn2+ Fluorophores, Kinetic, and X-ray Crystallographic Study]] | ||
*[[Journal:JBIC:16|Laue Crystal Structure of ''Shewanella oneidensis'' Cytochrome c Nitrite Reductase from a High-yield Expression System]] | *[[Journal:JBIC:16|Laue Crystal Structure of ''Shewanella oneidensis'' Cytochrome c Nitrite Reductase from a High-yield Expression System]] | ||
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*[[Journal:JBIC:7|Structural and kinetic studies of imidazole binding to two members of the cytochrome c6 family reveal an important role for a conserved heme pocket residue]] | *[[Journal:JBIC:7|Structural and kinetic studies of imidazole binding to two members of the cytochrome c6 family reveal an important role for a conserved heme pocket residue]] | ||
*[[Journal:JBIC:9|Protein and metal cluster structure of the wheat metallothionein domain γ-Ec-1. The second part of the puzzle.]] | *[[Journal:JBIC:9|Protein and metal cluster structure of the wheat metallothionein domain γ-Ec-1. The second part of the puzzle.]] | ||
- | *[[Ferredoxin]] | ||
*[[Journal:JBIC:11|{{nowrap|A Cryo-Crystallographic}} Time Course for Peroxide Reduction by Rubrerythrin from ''Pyrococcus furiosus'']] | *[[Journal:JBIC:11|{{nowrap|A Cryo-Crystallographic}} Time Course for Peroxide Reduction by Rubrerythrin from ''Pyrococcus furiosus'']] | ||
*[[Journal:JMB:1|Cyt1Aa Toxin: High Resolution Structure Reveals Implications for its Membrane-Perforating Function]] | *[[Journal:JMB:1|Cyt1Aa Toxin: High Resolution Structure Reveals Implications for its Membrane-Perforating Function]] | ||
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*[[Journal:JBSD:40|Traditional Chinese medicine application in HIV: An ''in silico'' study]] | *[[Journal:JBSD:40|Traditional Chinese medicine application in HIV: An ''in silico'' study]] | ||
*[[Journal:JBSD:41|Molecular Mechanism of HIV-1 gp120 Mutations That Reduce CD4 Binding Affinity]] | *[[Journal:JBSD:41|Molecular Mechanism of HIV-1 gp120 Mutations That Reduce CD4 Binding Affinity]] | ||
+ | *[[Book:Structural Proteomics and its Impact on the Life Sciences:6]] | ||
+ | *[[Journal:Acta Cryst D:S0907444911047251|Flexibility of the flap in the active site of BACE1 as revealed by crystal structures and molecular dynamics simulations]] | ||
+ | *[[Journal:Acta Cryst D:S2059798318000050|A DNA structural alphabet provides new insight into DNA flexibility]] | ||
+ | *[[Journal:Acta Cryst D:S2059798319000676|Crystal structures of pyrrolidone-carboxylate peptidase I from ''Deinococcus radiodurans'' reveal the mechanism of L-pyroglutamate recognition]] | ||
+ | *[[Journal:Acta Cryst D:S2059798318014900|Structure of the AmyC GH13 alpha-amylase from Alicyclobacillus sp, reveals accommodation of starch branching points in the alpha-amylase family]] | ||
+ | *[[Journal:Acta Cryst D:S2059798318017047|The crystal structure of the N-acetylglucosamine 2-epimerase from Nostoc sp. KVJ10 reveals the true dimer]] | ||
+ | *[[Journal:Acta Cryst D:S2059798318015322|Structure of ISG15 from the bat species Myotis davidii and the impact of interdomain ISG15 interactions on viral protein engagement]] | ||
+ | *[[Journal:Acta Cryst D:S2059798319000214|In-house high energy remote SAD-phasing using the magic triangle: how to tackle the P1 low symmetry using multiple orientations on the same human IBA57 crystal to increase multiplicity]] | ||
+ | *[[Journal:Acta Cryst D:S2059798319002912|Crystal structure of the pseudoenzyme PDX1.2 in complex with its cognate enzyme PDX1.3]] | ||
+ | *[[Journal:Acta Cryst D:S2059798319007113|Crystal Structure Determination of ''Pseudomonas stutzeri'' A1501 endoglucanase Cel5A]] | ||
+ | *[[Journal:Acta Cryst D:S2059798319006995|Structural insight into a matured humanized monoclonal antibody HuA21 against HER2-overexpressing cancer cells]] | ||
+ | *[[Journal:Acta Cryst D:S2059798319002304|The third structural switch in the molecule of archaeal translation initiation factor 2 and its possible role in initiation of GTP hydrolysis and removal of aIF2 from the ribosome]] | ||
+ | *[[Journal:Acta Cryst D:S2059798319004169|Structural and functional insights into phosphomannose isomerase]] | ||
+ | *[[Journal:Acta Cryst F:S2053230X18016217|The structure of ''Mycobacterium tuberculosis'' HtrA reveals an auto-regulatory mechanism]] | ||
+ | *[[Journal:Acta Cryst F:S2053230X18014814|Crystal structure and kinetic analyses of a hexameric form of (S)-3-hydroxybutyryl-CoA dehydrogenase from Clostridium acetobutylicum]] | ||
+ | *[[Journal:Acta Cryst F:S2053230X19000815|Crystal structure of Type VI immunity protein Tdi1 (Atu4351) from Agrobacterium tumefaciens]] | ||
+ | *[[Journal:Acta Cryst F:S2053230X19004151|Phasing with calcium at home]] | ||
+ | *[[Journal:Acta Cryst F:S2053230X19001213|Substrate analogue complex structure of ''Mycobacterium tuberculosis'' decaprenyl diphosphate synthase]] | ||
+ | *[[Journal:Acta Cryst F:S2053230X19004618|Novel T9 loop interaction of Filamenting Temperature-sensitive mutant Z from ''Mycobacterium tuberculosis'']] | ||
+ | *[[Journal:Acta Cryst F:S1744309112050270|Crystal structure of ADL1, a plant-specific homologue of the universal diaminopimelate amino transferase enzyme of lysine biosynthesis]] | ||
+ | *[[Journal:Acta Cryst F:S2053230X19002863|Functional and structural characterization of IdnL7, an adenylation enzyme involved in incednine biosynthesis]] | ||
+ | *[[Journal:Acta Cryst F:S2053230X19004424|Structure of the Ebola virus nucleoprotein - RNA complex]] | ||
+ | *[[Journal:Acta Cryst F:S1744309112003326|Structure of recombinant human carboxylesterase 1 isolated from whole cabbage looper larvae]] | ||
+ | *[[Journal:Acta Cryst F:S2053230X18018083|An assessment of three human methylenetetrahydrofolate dehydrogenase/cyclohydrolase ligand complexes following further refinement]] | ||
+ | *[[Journal:Acta Cryst F:S2053230X19002693|Crystal structure of phosphoribulokinase from ''Synechococcus sp.'' strain PCC 6301]] | ||
+ | *[[Journal:Acta Cryst F:S1744309112003326|Structure of recombinant human carboxylesterase 1 isolated from whole cabbage looper larvae]] | ||
+ | *[[Journal:Acta Cryst F:S2053230X19007192|Crystal Structure of Flavin Dependent Thymidylate Synthase, Thy1, from ''Thermus thermophilus'' having an Extra C Terminal Domain]] | ||
+ | *[[Journal:BMC:3|Identification of novel isocytosine derivatives as xanthine oxidase inhibitors from a set of virtual screening hits]] | ||
+ | *[[Journal:FEBS Open Bio:2|Structural evidence for Arabidopsis glutathione transferase AtGSTF2 functioning as a transporter of small organic ligands]] | ||
+ | *[[Journal:IUCrJ:S2052252519002926|Determination of the Molecular Basis for Coprogen Import by Gram Negative Bacteria]] | ||
+ | *[[Journal:IUCrJ:S2052252519001568|Structure of mammalian plasma fetuin-B and its mechanism of selective metallopeptidase inhibition]] | ||
+ | *[[Journal:IUCrJ:S2052252518018274|A cytosine modification mechanism revealed by the ternary complex structure of deoxycytidylate hydroxymethylase from bacteriophage T4 with its cofactor and substrate]] | ||
+ | *[[Journal:IUCrJ:S2052252519005372|The structural characterisation of a glucosylglycerate hydrolase provides insights into the molecular mechanism of mycobacterial recovery from nitrogen starvation]] | ||
+ | *[[Journal:IUCrJ:S2052252519005761|Room-temperature photo-induced martensitic transformation in a protein crystal]] | ||
+ | *[[SUMO]] | ||
+ | *[[EPSP synthase]] | ||
+ | *[[AMP-activated protein kinase]] | ||
+ | *[[Xanthine dehydrogenase]] | ||
+ | *[[Nicotinic Acetylcholine Receptor]] | ||
*[[Cytochrome c]] | *[[Cytochrome c]] | ||
*[[Methotrexate]] | *[[Methotrexate]] | ||
+ | *[[Kemp elimination catalyst]] | ||
*[[Urease]] | *[[Urease]] | ||
*[[Phosphoglycerate Kinase]] | *[[Phosphoglycerate Kinase]] | ||
+ | *[[Plant-derived glucocerebrosidase]] | ||
*[[NADH quinone oxidoreductase (NQO1) with inhibitor dicoumarol]] | *[[NADH quinone oxidoreductase (NQO1) with inhibitor dicoumarol]] | ||
+ | *[[Matrix metalloproteinase]] | ||
+ | *[[Amino acid oxidase]] | ||
+ | *[[Mutant immunity protein 9 (variant R12-13)]] | ||
+ | *[[Acetylcholine binding protein]] | ||
+ | *[[Hydroxylase]] | ||
+ | *[[Actin]] | ||
+ | *[[Torpedo Californica Acetylcholinesterase in complex with an (R)-Tacrine-(10)-Hupyridone inhibitor]] | ||
+ | *[[Dronpa]] | ||
+ | *[[Major histocompatibility complex]] | ||
+ | *[[Mutant immunity protein 9 (variant R12-2)]] | ||
+ | *[[Butyrylcholinesterase]] | ||
+ | *[[Human acid-beta-glucosidase covalently bound to conduritol B epoxide]] | ||
+ | *[[Avidin]] | ||
+ | *[[Proteasome]] | ||
+ | *[[FK506 binding protein]] | ||
+ | *[[Insecticidal delta-endotoxin Cyt2Ba from Bacillus thuringiensis]] | ||
+ | *[[Ubiquitin protein ligase]] | ||
+ | *[[Catalase]] | ||
+ | *[[Albumin]] | ||
+ | *[[Aminopeptidase]] | ||
+ | *[[Staphylococcal nuclease]] | ||
+ | *[[Virus protease]] | ||
+ | *[[Asparaginase]] | ||
+ | *[[NAC transcription factor]] | ||
+ | *[[Kemp eliminase]] | ||
+ | *[[NADPH-Cytochrome P450 Reductase]] | ||
+ | *[[Prolyl hydroxylase domain]] | ||
+ | *[[Neuraminidase]] | ||
+ | *[[Carbonic anhydrase]] | ||
+ | *[[Carboxypeptidase]] | ||
+ | *[[ABC transporter]] | ||
+ | *[[Ubiquitin]] | ||
+ | *[[Cytochrome P450]] | ||
+ | *[[TEM1-beta-Lactamase/beta-lactamase Inhibitor Protein (BLIP)]] | ||
+ | *[[Acid beta-glucosidase with N-butyl-deoxynojirimycin]] | ||
+ | *[[Treatment of Gaucher disease]] | ||
+ | *[[Acyl carrier protein synthase]] | ||
+ | *[[Chimeras of alcohol dehydrogenases]] | ||
+ | *[[Dihydrodipicolinate synthase]] | ||
+ | *[[Directed evolution]] | ||
+ | *[[Colicin Immunity Protein]] | ||
+ | *[[Human FKBP52]] | ||
+ | *[[Opioid receptor]] | ||
+ | *[[Acetylcholine]] | ||
+ | *[[Heat Shock Proteins]] | ||
+ | *[[Dioxygenase]] | ||
+ | *[[Flavodoxin]] | ||
+ | *[[Phospholipase A2]] | ||
+ | *[[Tyrosine kinase]] | ||
+ | *[[Cellobiohydrolase]] | ||
+ | *[[Acid phosphatase]] | ||
+ | *[[Neuroglobin]] | ||
+ | *[[Hirudin]] | ||
+ | *[[GTP-binding protein]] | ||
+ | *[[Aldehyde dehydrogenase]] | ||
+ | *[[Delta-endotoxin]] | ||
+ | *[[Beta-lactamase]] | ||
+ | *[[Estrogen receptor]] | ||
+ | *[[DNA-binding protein VirE2 from Agrobacterium tumefaciens complexed with chaperone VirE1]] | ||
+ | *[[Alkaline phosphatase]] | ||
+ | *[[Cathepsin]] | ||
+ | *[[Prolyl Endopeptidase]] | ||
+ | *[[Forkhead box protein]] | ||
+ | *[[Subtilisin]] | ||
+ | *[[Hyaluronidase]] | ||
+ | *[[Lysine-specific histone demethylase]] | ||
+ | *[[Glycolate oxidase]] | ||
+ | *[[Chaperonin]] | ||
+ | *[[Nucleoprotein]] | ||
+ | *[[Transcriptional activator]] | ||
+ | *[[Chitinase]] | ||
+ | *[[Cluster of Differentiation CD38]] | ||
+ | *[[Tubulin]] | ||
+ | *[[SAM-dependent methyltransferase]] | ||
+ | *[[Lignin peroxidase]] | ||
+ | *[[Gyrase]] | ||
+ | *[[Methylesterase]] | ||
+ | *[[CAMP-dependent protein kinase]] | ||
+ | *[[Plasminogen]] | ||
+ | *[[Choline Oxidase]] | ||
+ | *[[Thioesterase]] | ||
+ | *[[Dopamine receptor]] | ||
+ | *[[Mitogen-activated protein kinase kinase]] | ||
+ | *[[Kinesin]] | ||
+ | *[[Gelsolin]] | ||
+ | *[[DNA glycosylase]] | ||
+ | *[[Mitogen-activated protein kinase]] | ||
+ | *[[Factor VIII]] | ||
+ | *[[BtuB]] | ||
+ | *[[BLUF domain protein]] | ||
+ | *[[Botulinum neurotoxin]] | ||
+ | *[[Blue copper oxidase CueO]] | ||
+ | *[[Beta-phosphoglucomutase]] | ||
+ | *[[Beta-ketoacyl-ACP reductase]] | ||
+ | *[[Beta-adrenergic receptor kinase]] | ||
+ | *[[Barnase]] | ||
+ | *[[Bacteriorhodopsin]] | ||
+ | *[[BA42]] | ||
+ | *[[Gramicidin]] | ||
+ | *[[Horseradish peroxidase]] | ||
+ | *[[Azurin]] | ||
+ | *[[Avirulence protein]] | ||
+ | *[[Autophagy-related protein]] | ||
+ | *[[ATP-citrate synthase]] | ||
+ | *[[Atlastin]] | ||
+ | *[[Catabolite gene activator protein]] | ||
+ | *[[Cytochrome bc1 complex]] | ||
+ | *[[Lactoferrin]] | ||
+ | *[[Glycosyltransferase]] | ||
+ | *[[Factor inhibiting HIF]] | ||
+ | *[[Ephrin receptor]] | ||
+ | *[[Aspartoacylase]] | ||
+ | *[[Aspartate carbamoyltransferase]] | ||
+ | *[[Proliferating Cell Nuclear Antigen]] | ||
+ | *[[Aspartate-semialdehyde dehydrogenase]] | ||
+ | *[[Ascorbate peroxidase]] | ||
+ | *[[Aromatic amine dehydrogenase]] | ||
+ | *[[Arginine kinase]] | ||
+ | *[[Antigen 85]] | ||
+ | *[[Anti-sigma factor antagonist]] | ||
+ | *[[Anthrax protective antigen]] | ||
+ | *[[Anthrax edema factor]] | ||
+ | *[[Annexin]] | ||
+ | *[[Aminotransferase]] | ||
+ | *[[Alpha-tubulin N-acetyltransferase]] | ||
+ | *[[Alpha-lytic protease]] | ||
+ | *[[Aldose Reductase]] | ||
+ | *[[Alanine racemase]] | ||
+ | *[[Agglutinin]] | ||
+ | *[[ADP-ribose pyrophosphatase]] | ||
+ | *[[Poly (ADP-ribose) polymerase]] | ||
+ | *[[Adenylosuccinate lyase]] | ||
+ | *[[Adenosine kinase]] | ||
+ | *[[Adenosine deaminase]] | ||
+ | *[[Adenosine A2A receptor]] | ||
+ | *[[Adaptin]] | ||
+ | *[[Acylaminoacyl peptidase]] | ||
+ | *[[Acyl carrier protein]] | ||
+ | *[[Acyl-CoA dehydrogenase]] | ||
+ | *[[Acetylxylan esterase]] | ||
+ | *[[Acetyl-CoA carboxylase]] | ||
+ | *[[Acetyl-CoA synthetase]] | ||
+ | *[[Acetyl-CoA synthase]] | ||
+ | *[[Cytochrome c oxidase]] | ||
+ | *[[Concanavalin A]] | ||
+ | *[[Neurexin]] | ||
+ | *[[Histone deacetylase]] | ||
+ | *[[Purine repressor]] | ||
+ | *[[Protein phosphatase]] | ||
+ | *[[Glutamate synthase]] | ||
+ | *[[4-hydroxy-3-methylbut-2-enyl diphosphate reductase]] | ||
+ | *[[6-aminohexanoate-dimer hydrolase]] | ||
+ | *[[6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase]] | ||
+ | *[[7,8-dihydro-8-oxoguanine triphosphatase]] | ||
+ | *[[Cell division protein]] | ||
+ | *[[Carbon monoxide dehydrogenase]] | ||
+ | *[[CXC chemokine receptor]] | ||
+ | *[[Cyclin-dependent kinase]] | ||
+ | *[[12-oxophytodienoate reductase]] | ||
+ | *[[Enoyl-Acyl-Carrier Protein Reductase]] | ||
+ | *[[Dihydrolipoamide acetyltransferase]] | ||
+ | *[[Alpha-glucosidase]] | ||
+ | *[[Apoptotic protease-activating factor]] | ||
+ | *[[Arginase]] | ||
+ | *[[Adhesin]] | ||
+ | *[[Arabinanase]] | ||
+ | *[[Gp120]] | ||
+ | *[[GMP synthase]] | ||
+ | *[[Leukotriene A4 Hydrolase]] | ||
+ | *[[Biotin Protein Ligase]] | ||
+ | *[[Androgen receptor]] | ||
+ | *[[Glutamate dehydrogenase]] | ||
+ | *[[14-3-3 protein]] | ||
+ | *[[Fibrin]] | ||
+ | *[[3C protease]] | ||
+ | *[[GTPase KRas]] | ||
+ | *[[6-phosphogluconate dehydrogenase]] | ||
+ | *[[Mineralocorticoid receptor]] | ||
+ | *[[Thyroid hormone receptor]] | ||
+ | *[[Progesterone receptor]] | ||
+ | *[[Serpin]] | ||
+ | *[[Leucine transporter]] | ||
+ | *[[Microtubule-associated protein]] | ||
+ | *[[Ectonucleotide pyrophosphatase/phosphodiesterase]] | ||
+ | *[[Ribosome biogenesis protein]] | ||
+ | *[[Liver X receptor]] | ||
+ | *[[Nitrophorin]] | ||
+ | *[[VprBP]] | ||
+ | *[[Growth factor receptor-bound protein]] | ||
+ | *[[CREB-binding protein]] | ||
+ | *[[Kdo-8-phosphate synthase]] | ||
+ | *[[Signal recognition particle receptor]] | ||
+ | *[[Liver receptor homolog-1]] | ||
+ | *[[Orexin and Orexin receptor]] | ||
+ | *[[Spindlin]] | ||
+ | *[[Prostaglandin E synthase]] | ||
+ | *[[Terminase]] | ||
+ | *[[Mandelate racemase/muconate lactonizing enzyme]] | ||
+ | *[[GABA(A) receptor-associated protein]] | ||
+ | *[[IspG]] | ||
+ | *[[Haloperoxidase]] | ||
+ | *[[Cytochrome P450 hydroxylase]] | ||
+ | *[[Period circadian protein]] | ||
+ | *[[Proteinase]] | ||
+ | *[[Sialyltransferase]] | ||
+ | *[[Neprilysin]] | ||
+ | *[[Cholesterol esterase]] | ||
+ | *[[Chloramphenicol acetyltransferase]] | ||
+ | *[[Thiolase]] | ||
+ | *[[CCA-adding enzyme]] | ||
+ | *[[Glucose-fructose oxidoreductase]] | ||
+ | *[[Tripeptidyl peptidase]] | ||
+ | *[[Tryptophan synthase]] | ||
+ | *[[Fatty acid synthase]] | ||
+ | *[[Glucosamine 6-phosphate synthase]] | ||
+ | *[[Rho GTPase activating protein]] | ||
+ | *[[Ornithine decarboxylase]] | ||
+ | *[[Prostaglandin D synthase]] | ||
+ | *[[Prestin]] | ||
+ | *[[Polyamine oxidase]] | ||
+ | *[[Phosphotransferase]] | ||
+ | *[[Phosphodiesterase]] | ||
+ | *[[Plexin]] | ||
+ | *[[Plasminogen activator]] | ||
+ | *[[Plasmid segregation protein ParM]] | ||
+ | *[[Phospholipase C]] | ||
+ | *[[Phosphoenolpyruvate carboxylase]] | ||
+ | *[[Peptide N-glycanase]] | ||
+ | *[[Penicillopepsin]] | ||
+ | *[[Penicillin acylase]] | ||
+ | *[[PCSK9]] | ||
+ | *[[Galactose-binding lectin]] | ||
+ | *[[Paired box protein]] | ||
+ | *[[D-xylose isomerase]] | ||
+ | *[[Adrenodoxin reductase]] | ||
+ | *[[Methylamine dehydrogenase]] | ||
+ | *[[Oligopeptide-binding protein]] | ||
+ | *[[Met repressor]] | ||
+ | *[[Nuclear receptor coactivator]] | ||
+ | *[[Neuropilin]] | ||
+ | *[[NADH peroxidase]] | ||
+ | *[[Deoxyuridine 5'-triphosphate nucleotidohydrolase]] | ||
+ | *[[LDL receptor]] | ||
+ | *[[P63]] | ||
+ | *[[Galactose oxidase]] | ||
+ | *[[Leukotriene B4 hydroxydehydrogenase]] | ||
+ | *[[Leukocyte immunoglobulin-like receptor]] | ||
+ | *[[Alpha-lactalbumin]] | ||
+ | *[[3-phosphoinositide-dependent protein kinase 1]] | ||
+ | *[[2-isopropylmalate synthase]] | ||
+ | *[[Kelch-like protein]] | ||
+ | *[[Lactoperoxidase]] | ||
+ | *[[Mur ligase]] | ||
+ | *[[Calcineurin]] | ||
+ | *[[S100 protein]] | ||
+ | *[[Ecotin]] | ||
+ | *[[Leukotriene C4 synthase]] | ||
+ | *[[Jumonji domain-containing protein]] | ||
+ | *[[Monooxygenase]] | ||
+ | *[[Vanillyl-alcohol oxidase]] | ||
+ | *[[Isopropylmalate dehydrogenase]] | ||
+ | *[[Tumor necrosis factor]] | ||
+ | *[[Tumor necrosis factor receptor]] | ||
+ | *[[Mannosidase]] | ||
+ | *[[Transthyretin]] | ||
+ | *[[Transport inhibitor response 1]] | ||
+ | *[[Transducin]] | ||
+ | *[[Nitrate reductase]] | ||
+ | *[[Nitroreductase]] | ||
+ | *[[Dihydroorotate dehydrogenase]] | ||
+ | *[[L-rhamnose isomerase]] | ||
+ | *[[TRAIL]] | ||
+ | *[[Estrogen-related receptor]] | ||
+ | *[[Inosine monophosphate dehydrogenase]] | ||
+ | *[[Survivin]] | ||
+ | *[[UDP-N-acetylglucosamine acyltransferase]] | ||
+ | *[[Haptoglobin receptor]] | ||
+ | *[[D-alanine-D-alanine ligase]] | ||
+ | *[[Glutaminyl cyclase]] | ||
+ | *[[Severin]] | ||
+ | *[[Carnitine palmitoyltransferase]] | ||
+ | *[[Isoaspartyl dipeptidase]] | ||
+ | *[[Thiaminase]] | ||
+ | *[[Acetylcholinesterase with OTMA]] | ||
+ | *[[D275P mutant of alcohol dehydrogenase from protozoa Entamoeba histolytica]] | ||
+ | *[[Ferripyoverdine receptor]] | ||
+ | *[[Fatty acid-binding protein]] | ||
+ | *[[Rho-associated protein kinase]] | ||
+ | *[[Endonuclease]] | ||
+ | *[[Collagenase (non-MMP)]] | ||
+ | *[[Epoxidase]] | ||
+ | *[[Ferrochelatase]] | ||
+ | *[[Elastase]] | ||
+ | *[[Tyrosinase]] | ||
+ | *[[N-acetylornithine carbamoyltransferase]] | ||
+ | *[[Ornithine carbamoyltransferase]] | ||
+ | *[[Pantothenate kinase]] | ||
+ | *[[Pantothenate synthetase]] | ||
+ | *[[Parvalbumin]] | ||
+ | *[[Cephalosporin acylase]] | ||
+ | *[[Dipeptidyl peptidase]] | ||
+ | *[[Farnesyltransferase]] | ||
+ | *[[Farnesyl diphosphate synthase]] | ||
+ | *[[Arginine repressor]] | ||
+ | *[[Transferrin]] | ||
+ | *[[Transketolase]] | ||
+ | *[[Dihydropteroate synthase]] | ||
+ | *[[Trichodiene synthase]] | ||
+ | *[[DAHP synthase]] | ||
+ | *[[Trehalulose synthase]] | ||
+ | *[[TRNA-guanine transglycosylase]] | ||
+ | *[[Cyclophilin]] | ||
+ | *[[Cutinase]] | ||
+ | *[[Trypanothione reductase]] | ||
+ | *[[Trypsin inhibitor]] | ||
+ | *[[Tryptase]] | ||
+ | *[[Tubulin tyrosine ligase]] | ||
+ | *[[Transaldolase]] | ||
+ | *[[Urokinase]] | ||
+ | *[[Undecaprenyl pyrophosphate synthase]] | ||
+ | *[[UDP-galactose 4-epimerase]] | ||
+ | *[[Uridine 5'-monophosphate synthase]] | ||
+ | *[[Arsenate reductase]] | ||
+ | *[[Rac]] | ||
+ | *[[Rho GTPase]] | ||
+ | *[[Carbamoyl phosphate synthetase]] | ||
+ | *[[Dedicator of cytokinesis protein]] | ||
+ | *[[Phosphoribosylaminoimidazole carboxylase]] | ||
+ | *[[Retinoid isomerohydrolase]] | ||
+ | *[[Calcium uptake protein 1]] | ||
+ | *[[Abscisic acid receptor]] | ||
+ | *[[Apoptosis-inducing factor]] | ||
+ | *[[Nucleolin]] | ||
+ | *[[Aldo-keto reductase]] | ||
+ | *[[SAICAR synthetase]] | ||
+ | *[[Prolactin receptor]] | ||
+ | *[[Siderocalin]] | ||
+ | *[[Latrophilin]] | ||
+ | *[[Folypolyglutamate synthase]] | ||
+ | *[[WD repeat-containing protein]] | ||
+ | *[[Xylosidase]] | ||
+ | *[[Uridylate kinase]] | ||
+ | *[[Penicillin-binding protein]] | ||
+ | *[[Pentaerythritol tetranitrate reductase]] | ||
+ | *[[Thymidine kinase]] | ||
+ | *[[Thymidylate kinase]] | ||
+ | *[[Tissue factor pathway inhibitor]] | ||
+ | *[[Thioredoxin Reductase]] | ||
+ | *[[Peptidyl-tRNA hydrolase]] | ||
+ | *[[Peroxiredoxin]] | ||
+ | *[[Phenylethanolamine N-methyltransferase]] | ||
+ | *[[Tetracycline repressor protein]] | ||
+ | *[[Phenylpyruvate decarboxylase]] | ||
+ | *[[Succinate-semialdehyde dehydrogenase]] | ||
+ | *[[Spermidine/spermine N-acetyltransferase]] | ||
+ | *[[Sulfotransferase]] | ||
+ | *[[Phosphomannomutase]] | ||
+ | *[[Strictosidine Synthase]] | ||
+ | *[[Phosphoenolpyruvate carboxykinase]] | ||
+ | *[[Phosphoribosyltransferase]] | ||
+ | *[[Phosphoserine aminotransferase]] | ||
+ | *[[Phosphoserine phosphatase]] | ||
+ | *[[Shikimate kinase]] | ||
+ | *[[Shikimate dehydrogenase]] | ||
+ | *[[Selectin]] | ||
+ | *[[Selenocysteine synthase]] | ||
+ | *[[Semaphorin]] | ||
+ | *[[Serine palmitoyltransferase]] | ||
+ | *[[SAM decarboxylase]] | ||
+ | *[[SAM synthetase]] | ||
+ | *[[S-adenosylhomocysteine hydrolase]] | ||
+ | *[[Plasmepsin]] | ||
+ | *[[RNA uridylyltransferase]] | ||
+ | *[[Ribosomal protein S6 kinase]] | ||
+ | *[[Poly(A) RNA polymerase protein Cid1]] | ||
+ | *[[Ribonucleotide reductase]] | ||
+ | *[[Phycocyanobilin:ferredoxin oxidoreductase]] | ||
+ | *[[Poly (ADP-ribose) glycohydrolase]] | ||
+ | *[[Rhomboid protease]] | ||
+ | *[[Rhodopsin kinase]] | ||
+ | *[[Retinol-binding protein]] | ||
+ | *[[Polyneuridine Aldehyde Esterase]] | ||
+ | *[[Retinoid X receptor]] | ||
+ | *[[Porphobilinogen synthase]] | ||
+ | *[[Retinoblastoma-binding protein]] | ||
+ | *[[Pyruvate dehydrogenase kinase]] | ||
+ | *[[Pyruvate-ferredoxin oxidoreductase]] | ||
+ | *[[Pyrroline-5-carboxylate dehydrogenase]] | ||
+ | *[[Purine nucleoside phosphorylase]] | ||
+ | *[[Proline utilization A]] | ||
+ | *[[Protein kinase C]] | ||
+ | *[[Nucleoside diphosphate kinase]] | ||
+ | *[[Formate dehydrogenase]] | ||
+ | *[[NAD synthase]] | ||
+ | *[[Nuclear transcription factor Y]] | ||
+ | *[[Methanol dehydrogenase]] | ||
+ | *[[Matriptase]] | ||
+ | *[[Manganese peroxidase]] | ||
+ | *[[Mandelate racemase]] | ||
+ | *[[MEP cytidylyltransferase]] | ||
+ | *[[Mandelate dehydrogenase]] | ||
+ | *[[Malate synthase]] | ||
+ | *[[Macrophage inhibitory factor]] | ||
+ | *[[Homocitrate synthase]] | ||
+ | *[[Hemagglutinin-esterase]] | ||
+ | *[[Guanylate kinase]] | ||
+ | *[[Granzyme]] | ||
+ | *[[Glycosylasparaginase]] | ||
+ | *[[Glutaryl-CoA dehydrogenase]] | ||
+ | *[[Glutaminase]] | ||
+ | *[[Glutamate racemase]] | ||
+ | *[[Glucuronidase]] | ||
+ | *[[Glucose-1-phosphate thymidylyltransferase]] | ||
+ | *[[Geranylgeranyl transferase]] | ||
+ | *[[Galactose mutarotase]] | ||
+ | *[[Ficolin]] | ||
+ | *[[Phosphoinositide phosphatase]] | ||
+ | *[[Ferredoxin thioredoxin reductase]] | ||
+ | *[[PcrH]] | ||
+ | *[[Exportin]] | ||
+ | *[[Exoenzyme]] | ||
+ | *[[Epoxide hydrolase]] | ||
+ | *[[Elongation factor]] | ||
+ | *[[DNA damage-binding protein]] | ||
+ | *[[DNA adenine methylase]] | ||
+ | *[[Glucose 6-phosphate dehydrogenase]] | ||
+ | *[[Diphthine synthase]] | ||
+ | *[[Cytochrome f]] | ||
+ | *[[Cullin]] | ||
+ | *[[Cruzain]] | ||
+ | *[[Complement C3]] | ||
+ | *[[Formyl-CoA transferase]] | ||
+ | *[[Ferric hydroxamate uptake receptor]] | ||
+ | *[[Enoylpyruvate transferase]] | ||
+ | *[[Enoyl-CoA hydratase]] | ||
+ | *[[Cholesterol oxidase]] | ||
+ | *[[Ceruloplasmin]] | ||
+ | *[[Calpain]] | ||
+ | *[[DXP reductoisomerase]] | ||
+ | *[[Diphtheria toxin]] | ||
+ | *[[Diphtheria toxin repressor]] | ||
+ | *[[Diguanylate cyclase]] | ||
+ | *[[Dehydroquinase]] | ||
+ | *[[Dehaloperoxidase]] | ||
+ | *[[Death-associated protein kinase]] | ||
+ | *[[D-aminoacylase]] | ||
+ | *[[Cytochrome c peroxidase]] | ||
+ | *[[Cytochrome b5]] | ||
+ | *[[Cyclohydrolase]] | ||
+ | *[[Cocaine esterase]] | ||
+ | *[[CotA laccase]] | ||
+ | *[[Colicin I receptor]] | ||
+ | *[[Choline O-acetyltransferase]] | ||
+ | *[[Choline kinase]] | ||
+ | *[[5'-deoxy-5'-methylthioadenosine phosphorylase]] | ||
+ | *[[CD4]] | ||
+ | *[[Casein kinase]] | ||
+ | *[[Nitrile hydratase]] | ||
+ | *[[UDP-3-O-acyl-N-acetylglucosamine deacetylase]] | ||
+ | *[[Chitinase-3-like protein]] | ||
+ | *[[Insulin-like growth factor receptor]] | ||
+ | *[[Ribose-binding protein]] | ||
+ | *[[Nitrite reductase]] | ||
+ | *[[DNA methyltransferase]] | ||
+ | *[[Pre-mRNA-splicing factor]] | ||
+ | *[[Carboxylesterase]] | ||
+ | *[[Ankyrin]] | ||
+ | *[[Acetylcholinesterase with DFP]] | ||
+ | *[[IFG/DG-Cerezyme]] | ||
+ | *[[C-terminal portion of human eIF4GI]] | ||
+ | *[[Death Associated Protein 5]] | ||
+ | *[[Acetylcholinesterase complexed with N-9-(1',2',3',4'-tetrahydroacridinyl)-1,8-diaminooctane]] | ||
+ | *[[Torpedo californica acetylcholinesterase with alkylene-linked tacrine dimer (5 carbon linker)]] | ||
+ | *[[Thioredoxin Glutathione Reductase]] | ||
+ | *[[Journal:PMC:1]] |
Current revision
Dr. Alexander Berchansky, Ph.D., Israel Structural Proteomics Center, Weizmann Institute of Science
My interesting pages:
- Acetylcholinesterase
- AChE inhibitors and substrates
- Mutations in BRCA1/BARD1 RING-domain heterodimer
- Mutations in Brca1 BRCT Domains
- Lactate Dehydrogenase
- Human Acetylcholinesterase
- Missense Mutations in Phenylalanine Hydroxylase
- Ferredoxin
- Phosphofructokinase (PFK)
- Alcohol dehydrogenase
- Beta-glucosidase
- Aricept Complexed with Acetylcholinesterase (Hebrew)
- Aricept Complexed with Acetylcholinesterase (Russian)
- Prion
- Viral capsids
- Lattice-translocation defects in some specific crystals of the catalytic head domain of influenza neuraminidase, Linghui Li, Shuliu Dai, George F. Gao and Jiawei Wang http://dx.doi.org/10.1107/S2059798320011869
- Proteins from Mycobacterium tuberculosis
- Treatment of Tuberculosis
- Iron–sulfur proteins
- Hemeproteins
- Neurotransmitters
- Growth factors
- Receptor
- Hormones and their receptors
CRISPR-Cas (under development):
Classification according to the Wikipedia page CRISPR [1] with additions
CRISPR Class 1 uses a complex of multiple Cas proteins
CRISPR type I (Cas3)
CRISPR type I-A (Cascade) - see CRISPR subtype I-A
CRISPR type I-B (Cascade) - see CRISPR subtype I-B
CRISPR type I-C (Cascade) - see CRISPR subtype I-C
CRISPR type I-D (Cas10d)
CRISPR type I-E (Cascade) - see CRISPR subtype I-E
CRISPR type I-F (Csy1, Csy2, Csy3) - see CRISPR subtype I-F
CRISPR type I-U (GSU0054)
CRISPR type III (Cas10)
CRISPR type III-A (Csm complex) - see CRISPR subtype III-A (Csm complex)
CRISPR type III-B (Cmr complex)
CRISPR type III-C (Cas10 or Csx11)
CRISPR type III-D (Csx10)
CRISPR type Orphan
CRISPR type IV (Csf1)
CRISPR type IV-A
CRISPR type IV-B
CRISPR Class 2 uses a single large Cas protein
CRISPR type II-A - see CRISPR-Cas9
CRISPR type II-B (Cas4)
CRISPR type II-C
CRISPR type V (Cpf1, C2c1, C2c3) - see CRISPR type V
CRISPR type VI (Cas13a (previously known as C2c2), Cas13b, Cas13c, Cas13d) - see CRISPR type VI
- Torpedo californica acetylcholinesterase is stabilized by binding of a divalent metal ion to a novel and versatile 4D motif
- X-ray crystallography studies of RoAb13 bound to PIYDIN, a part of the CCR5 N-terminal domain
- Using Yeast Surface Display to Engineer a Soluble and Crystallizable Construct of HPK1
- The substrate binding in the bile acid transporter ASBTYf of Yersinia frederiksenii
- An engineered disulfide bridge traps and validates an outward-facing conformation in a bile acid transporter
- Structure of the human factor VIIa/soluble tissue factor with calcium, magnesium and rubidium
- Fine tuning of chlorophyll spectra by protein-induced ring deformation
- A hydrogen-bonding network formed by the B10-E7-E11 residues of a truncated hemoglobin from Tetrahymena pyriformis is critical for stability of bound oxygen and nitric oxide detoxification
- ISC-like [2Fe-2S] ferredoxin (FdxB) dimer from Pseudomonas putida JCM 20004: Structural and electron nuclear double resonance characterization
- N-Butylisocyanide Oxidation at the [NiFe4S4OHx]-cluster of CO Dehydrogenase
- Multifaceted SlyD from Helicobacter pylori: implication in [NiFe] hydrogenase maturation
- Statistically correcting dynamical electron scattering improves refinement of protein nanocrystals, including charge refinement of coordinated metals
- Potent Inhibition of Dinuclear Zinc(II) Peptidase, an Aminopeptidase from Aeromonas proteolytica, by 8-Quinolinol Derivatives: Inhibitor Design Based on Zn2+ Fluorophores, Kinetic, and X-ray Crystallographic Study
- Laue Crystal Structure of Shewanella oneidensis Cytochrome c Nitrite Reductase from a High-yield Expression System
- Peptidylglycine α-Hydroxylating Monooxygenase (PHM)-coordination of peroxide to CuM center. Structural and computational study
- Solution structure and dynamics of human S100A14
- The crystal structure of Sporosarcina pasteurii urease in a complex with citrate provides new hints for inhibitor design
- The mechanism of copper uptake by tyrosinase from Bacillus megaterium
- The crystal structure of an extracellular catechol oxidase from the ascomycete fungus Aspergillus oryzae
- Selectivity of Ni(II) and Zn(II) binding to Sporosarcina pasteurii UreE, a metallo-chaperone in the urease assembly: a calorimetric and crystallographic study
- Solution structure and metal ion binding sites of the human CPEB3 ribozyme's P4 domain
- Synthesis, characterization and binding properties towards CT-DNA and Lipoxygenase, of mixed ligand silver(I) complexes with 2-mercapto-thiazole and its derivatives and triphenylphosphine.
- Fluoride inhibition of Sporosarcina pasteurii urease: structure and thermodynamics
- Aromatic aldehydes at the active site of Aldehyde Oxidoreductase from Desulfovibrio gigas: Reactivity and Molecular Details of the Enzyme-Substrate and Enzyme-Product Interactions
- Crystallographic studies of [NiFe]-hydrogenase mutants: towards consensus structures for the elusive unready oxidized states
- High-resolution crystal structure of Z-DNA in complex with Cr3+ cations
- Structural Characterization of Metal Binding to a Cold-adapted Frataxin
- Conformational control of the binding of diatomic gases to cytochrome c’
- Analyzing the Catalytic Role of Active Site Residues in the Fe-Type Nitrile Hydratase from Comamonas testosteroni Ni1
- Structural characterization of zinc-bound Zmp1, a zinc-dependent metalloprotease secreted by Clostridium difficile
- Structural evidence for Arabidopsis glutathione transferase AtGSTF2 functioning as a transporter of small organic ligands
- Crystal structure of porcine pancreatic phospholipase A2 in complex with 2-methoxycyclohexa-2-5-diene-1,4-dione
- A DNA Structural Alphabet Distinguishes Structural Features of DNA Bound to Regulatory Proteins and in the Nucleosome Core Particle
- Structural and kinetic studies of imidazole binding to two members of the cytochrome c6 family reveal an important role for a conserved heme pocket residue
- Protein and metal cluster structure of the wheat metallothionein domain γ-Ec-1. The second part of the puzzle.
- A Cryo-Crystallographic Time Course for Peroxide Reduction by Rubrerythrin from Pyrococcus furiosus
- Cyt1Aa Toxin: High Resolution Structure Reveals Implications for its Membrane-Perforating Function
- Catalytic metal ion rearrangements underline promiscuity and evolvability of a metalloenzyme
- Structure of estradiol metal chelate and estrogen receptor complex: The basis for designing a new class of SERMs
- Structural and functional insights into a dodecameric molecular machine – The RuvBL1/RuvBL2 complex
- Automated computational design of human enzymes for high bacterial expression and stability
- Antiviral Activity of 3(2H)- and 6-Chloro-3(2H)-Isoflavenes against Highly Diverged, Neurovirulent Vaccine-Derived, Type2 Poliovirus Sewage Isolates
- Structural Basis of Enzymatic Activity for the Ferulic Acid Decarboxylase (FADase) from Enterobacter sp. Px6-4
- Structural and functional characterization of the interaction of the photosensitizing probe methylene blue with Torpedo californica acetylcholinesterase
- The Impact of Crystallization Conditions on Structure-Based Drug Design: a Case Study on the Methylene Blue/Acetylcholinesterase Complex
- Structural basis of transcription activation
- Promiscuous Protein Binding as a Function of Protein Stability
- An Insight to the Dynamics of Conserved Water Mediated Salt Bridge Interaction and Inter-Domain Recognition in hIMPDH Isoforms
- Elucidation by NMR solution of neurotensin in Small Unilamellar Vesicle environment: molecular surveys for neurotensin receptor recognition
- Dominant-negative Effects in Prion Diseases: Insights from Molecular Dynamics Simulations on Mouse Prion Protein Chimeras
- Influence of divalent magnesium ion on DNA: molecular dynamics simulation studies
- Evidence-based docking of the urease activation complex
- Carbon monoxide binding to the heme group at the dimeric interface modulates structure and copper accessibility in the Cu,Zn superoxide dismutase from Haemophilus ducreyi: in silico and in vitro evidences
- Para-(benzoyl)-phenylalanine as a potential inhibitor against LpxC of Leptospira spp.: Homology modeling, docking and molecular dynamics study
- Drug resistance mechanism of PncA in Mycobacterium Tuberculosis
- Mechanism of BAG1 repair on Parkinson’s disease-linked DJ1 mutation
- Traditional Chinese medicine as dual guardians against hypertension and cancer?
- The molecular origin of the MMR-dependent apoptosis pathway from dynamics analysis of MutSα-DNA complexes
- The extracellular subunit interface of the 5-HT3 receptors: a computational alanine scanning mutagenesis study
- DNA Conformation and Energy in Nucleosome Core: A Theoretical Approach
- Molecular modeling study for conformational changes of Sirtuin 2 due to substrate and inhibitor binding
- Crystal structure of the CN-hydrolase SA0302 from the pathogenic bacterium Staphylococcus aureus belonging to the Nit and NitFhit Branch of the nitrilase superfamily
- Insight into TPMT*23 Mutation Mis-folding Using Molecular Dynamics Simulation and Protein Structure Analysis
- Identification of structural motifs in the E2 glycoprotein of Chikungunya involved in virus - host interaction
- Molecular dynamics simulations of the thermal stability of tteRBP and ecRBP
- Investigation on the Site-Selective Binding of Bovine Serum Albumin by Erlotinib Hydrochloride
- Interhelical loops within the bHLH domain are determinant in maintaining TWIST1-DNA complexes
- Investigation of Silent Information Regulator 1 (Sirt1) Agonists from Traditional Chinese Medicine
- Han ethnicity-specific type 2 diabetic treatment from traditional Chinese medicine?
- Conformational dynamics of full-length inducible human Hsp70 derived from microsecond molecular dynamics simulations in explicit solvent
- Non-specificity and synergy at the binding site of the carboplatin-induced DNA adduct via molecular dynamics simulations of the MutSα-DNA recognition complex
- A Possible Strategy against Head and Neck Cancer: In Silico. Investigation of Three-in-One inhibitors
- Structural Insights into the South African HIV-1 Subtype C Protease: Impact of hinge region dynamics and flap flexibility in drug resistance
- Memory-Enhancement by Traditional Chinese Medicine?
- The remarkable efficiency of a Pin-II proteinase inhibitor sans two conserved disulfide bonds is due to enhanced flexibility and hydrogen-bond density in the reactive loop
- Traditional Chinese medicine application in HIV: An in silico study
- Molecular Mechanism of HIV-1 gp120 Mutations That Reduce CD4 Binding Affinity
- Book:Structural Proteomics and its Impact on the Life Sciences:6
- Flexibility of the flap in the active site of BACE1 as revealed by crystal structures and molecular dynamics simulations
- A DNA structural alphabet provides new insight into DNA flexibility
- Crystal structures of pyrrolidone-carboxylate peptidase I from Deinococcus radiodurans reveal the mechanism of L-pyroglutamate recognition
- Structure of the AmyC GH13 alpha-amylase from Alicyclobacillus sp, reveals accommodation of starch branching points in the alpha-amylase family
- The crystal structure of the N-acetylglucosamine 2-epimerase from Nostoc sp. KVJ10 reveals the true dimer
- Structure of ISG15 from the bat species Myotis davidii and the impact of interdomain ISG15 interactions on viral protein engagement
- In-house high energy remote SAD-phasing using the magic triangle: how to tackle the P1 low symmetry using multiple orientations on the same human IBA57 crystal to increase multiplicity
- Crystal structure of the pseudoenzyme PDX1.2 in complex with its cognate enzyme PDX1.3
- Crystal Structure Determination of Pseudomonas stutzeri A1501 endoglucanase Cel5A
- Structural insight into a matured humanized monoclonal antibody HuA21 against HER2-overexpressing cancer cells
- The third structural switch in the molecule of archaeal translation initiation factor 2 and its possible role in initiation of GTP hydrolysis and removal of aIF2 from the ribosome
- Structural and functional insights into phosphomannose isomerase
- The structure of Mycobacterium tuberculosis HtrA reveals an auto-regulatory mechanism
- Crystal structure and kinetic analyses of a hexameric form of (S)-3-hydroxybutyryl-CoA dehydrogenase from Clostridium acetobutylicum
- Crystal structure of Type VI immunity protein Tdi1 (Atu4351) from Agrobacterium tumefaciens
- Phasing with calcium at home
- Substrate analogue complex structure of Mycobacterium tuberculosis decaprenyl diphosphate synthase
- Novel T9 loop interaction of Filamenting Temperature-sensitive mutant Z from Mycobacterium tuberculosis
- Crystal structure of ADL1, a plant-specific homologue of the universal diaminopimelate amino transferase enzyme of lysine biosynthesis
- Functional and structural characterization of IdnL7, an adenylation enzyme involved in incednine biosynthesis
- Structure of the Ebola virus nucleoprotein - RNA complex
- Structure of recombinant human carboxylesterase 1 isolated from whole cabbage looper larvae
- An assessment of three human methylenetetrahydrofolate dehydrogenase/cyclohydrolase ligand complexes following further refinement
- Crystal structure of phosphoribulokinase from Synechococcus sp. strain PCC 6301
- Structure of recombinant human carboxylesterase 1 isolated from whole cabbage looper larvae
- Crystal Structure of Flavin Dependent Thymidylate Synthase, Thy1, from Thermus thermophilus having an Extra C Terminal Domain
- Identification of novel isocytosine derivatives as xanthine oxidase inhibitors from a set of virtual screening hits
- Structural evidence for Arabidopsis glutathione transferase AtGSTF2 functioning as a transporter of small organic ligands
- Determination of the Molecular Basis for Coprogen Import by Gram Negative Bacteria
- Structure of mammalian plasma fetuin-B and its mechanism of selective metallopeptidase inhibition
- A cytosine modification mechanism revealed by the ternary complex structure of deoxycytidylate hydroxymethylase from bacteriophage T4 with its cofactor and substrate
- The structural characterisation of a glucosylglycerate hydrolase provides insights into the molecular mechanism of mycobacterial recovery from nitrogen starvation
- Room-temperature photo-induced martensitic transformation in a protein crystal
- SUMO
- EPSP synthase
- AMP-activated protein kinase
- Xanthine dehydrogenase
- Nicotinic Acetylcholine Receptor
- Cytochrome c
- Methotrexate
- Kemp elimination catalyst
- Urease
- Phosphoglycerate Kinase
- Plant-derived glucocerebrosidase
- NADH quinone oxidoreductase (NQO1) with inhibitor dicoumarol
- Matrix metalloproteinase
- Amino acid oxidase
- Mutant immunity protein 9 (variant R12-13)
- Acetylcholine binding protein
- Hydroxylase
- Actin
- Torpedo Californica Acetylcholinesterase in complex with an (R)-Tacrine-(10)-Hupyridone inhibitor
- Dronpa
- Major histocompatibility complex
- Mutant immunity protein 9 (variant R12-2)
- Butyrylcholinesterase
- Human acid-beta-glucosidase covalently bound to conduritol B epoxide
- Avidin
- Proteasome
- FK506 binding protein
- Insecticidal delta-endotoxin Cyt2Ba from Bacillus thuringiensis
- Ubiquitin protein ligase
- Catalase
- Albumin
- Aminopeptidase
- Staphylococcal nuclease
- Virus protease
- Asparaginase
- NAC transcription factor
- Kemp eliminase
- NADPH-Cytochrome P450 Reductase
- Prolyl hydroxylase domain
- Neuraminidase
- Carbonic anhydrase
- Carboxypeptidase
- ABC transporter
- Ubiquitin
- Cytochrome P450
- TEM1-beta-Lactamase/beta-lactamase Inhibitor Protein (BLIP)
- Acid beta-glucosidase with N-butyl-deoxynojirimycin
- Treatment of Gaucher disease
- Acyl carrier protein synthase
- Chimeras of alcohol dehydrogenases
- Dihydrodipicolinate synthase
- Directed evolution
- Colicin Immunity Protein
- Human FKBP52
- Opioid receptor
- Acetylcholine
- Heat Shock Proteins
- Dioxygenase
- Flavodoxin
- Phospholipase A2
- Tyrosine kinase
- Cellobiohydrolase
- Acid phosphatase
- Neuroglobin
- Hirudin
- GTP-binding protein
- Aldehyde dehydrogenase
- Delta-endotoxin
- Beta-lactamase
- Estrogen receptor
- DNA-binding protein VirE2 from Agrobacterium tumefaciens complexed with chaperone VirE1
- Alkaline phosphatase
- Cathepsin
- Prolyl Endopeptidase
- Forkhead box protein
- Subtilisin
- Hyaluronidase
- Lysine-specific histone demethylase
- Glycolate oxidase
- Chaperonin
- Nucleoprotein
- Transcriptional activator
- Chitinase
- Cluster of Differentiation CD38
- Tubulin
- SAM-dependent methyltransferase
- Lignin peroxidase
- Gyrase
- Methylesterase
- CAMP-dependent protein kinase
- Plasminogen
- Choline Oxidase
- Thioesterase
- Dopamine receptor
- Mitogen-activated protein kinase kinase
- Kinesin
- Gelsolin
- DNA glycosylase
- Mitogen-activated protein kinase
- Factor VIII
- BtuB
- BLUF domain protein
- Botulinum neurotoxin
- Blue copper oxidase CueO
- Beta-phosphoglucomutase
- Beta-ketoacyl-ACP reductase
- Beta-adrenergic receptor kinase
- Barnase
- Bacteriorhodopsin
- BA42
- Gramicidin
- Horseradish peroxidase
- Azurin
- Avirulence protein
- Autophagy-related protein
- ATP-citrate synthase
- Atlastin
- Catabolite gene activator protein
- Cytochrome bc1 complex
- Lactoferrin
- Glycosyltransferase
- Factor inhibiting HIF
- Ephrin receptor
- Aspartoacylase
- Aspartate carbamoyltransferase
- Proliferating Cell Nuclear Antigen
- Aspartate-semialdehyde dehydrogenase
- Ascorbate peroxidase
- Aromatic amine dehydrogenase
- Arginine kinase
- Antigen 85
- Anti-sigma factor antagonist
- Anthrax protective antigen
- Anthrax edema factor
- Annexin
- Aminotransferase
- Alpha-tubulin N-acetyltransferase
- Alpha-lytic protease
- Aldose Reductase
- Alanine racemase
- Agglutinin
- ADP-ribose pyrophosphatase
- Poly (ADP-ribose) polymerase
- Adenylosuccinate lyase
- Adenosine kinase
- Adenosine deaminase
- Adenosine A2A receptor
- Adaptin
- Acylaminoacyl peptidase
- Acyl carrier protein
- Acyl-CoA dehydrogenase
- Acetylxylan esterase
- Acetyl-CoA carboxylase
- Acetyl-CoA synthetase
- Acetyl-CoA synthase
- Cytochrome c oxidase
- Concanavalin A
- Neurexin
- Histone deacetylase
- Purine repressor
- Protein phosphatase
- Glutamate synthase
- 4-hydroxy-3-methylbut-2-enyl diphosphate reductase
- 6-aminohexanoate-dimer hydrolase
- 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase
- 7,8-dihydro-8-oxoguanine triphosphatase
- Cell division protein
- Carbon monoxide dehydrogenase
- CXC chemokine receptor
- Cyclin-dependent kinase
- 12-oxophytodienoate reductase
- Enoyl-Acyl-Carrier Protein Reductase
- Dihydrolipoamide acetyltransferase
- Alpha-glucosidase
- Apoptotic protease-activating factor
- Arginase
- Adhesin
- Arabinanase
- Gp120
- GMP synthase
- Leukotriene A4 Hydrolase
- Biotin Protein Ligase
- Androgen receptor
- Glutamate dehydrogenase
- 14-3-3 protein
- Fibrin
- 3C protease
- GTPase KRas
- 6-phosphogluconate dehydrogenase
- Mineralocorticoid receptor
- Thyroid hormone receptor
- Progesterone receptor
- Serpin
- Leucine transporter
- Microtubule-associated protein
- Ectonucleotide pyrophosphatase/phosphodiesterase
- Ribosome biogenesis protein
- Liver X receptor
- Nitrophorin
- VprBP
- Growth factor receptor-bound protein
- CREB-binding protein
- Kdo-8-phosphate synthase
- Signal recognition particle receptor
- Liver receptor homolog-1
- Orexin and Orexin receptor
- Spindlin
- Prostaglandin E synthase
- Terminase
- Mandelate racemase/muconate lactonizing enzyme
- GABA(A) receptor-associated protein
- IspG
- Haloperoxidase
- Cytochrome P450 hydroxylase
- Period circadian protein
- Proteinase
- Sialyltransferase
- Neprilysin
- Cholesterol esterase
- Chloramphenicol acetyltransferase
- Thiolase
- CCA-adding enzyme
- Glucose-fructose oxidoreductase
- Tripeptidyl peptidase
- Tryptophan synthase
- Fatty acid synthase
- Glucosamine 6-phosphate synthase
- Rho GTPase activating protein
- Ornithine decarboxylase
- Prostaglandin D synthase
- Prestin
- Polyamine oxidase
- Phosphotransferase
- Phosphodiesterase
- Plexin
- Plasminogen activator
- Plasmid segregation protein ParM
- Phospholipase C
- Phosphoenolpyruvate carboxylase
- Peptide N-glycanase
- Penicillopepsin
- Penicillin acylase
- PCSK9
- Galactose-binding lectin
- Paired box protein
- D-xylose isomerase
- Adrenodoxin reductase
- Methylamine dehydrogenase
- Oligopeptide-binding protein
- Met repressor
- Nuclear receptor coactivator
- Neuropilin
- NADH peroxidase
- Deoxyuridine 5'-triphosphate nucleotidohydrolase
- LDL receptor
- P63
- Galactose oxidase
- Leukotriene B4 hydroxydehydrogenase
- Leukocyte immunoglobulin-like receptor
- Alpha-lactalbumin
- 3-phosphoinositide-dependent protein kinase 1
- 2-isopropylmalate synthase
- Kelch-like protein
- Lactoperoxidase
- Mur ligase
- Calcineurin
- S100 protein
- Ecotin
- Leukotriene C4 synthase
- Jumonji domain-containing protein
- Monooxygenase
- Vanillyl-alcohol oxidase
- Isopropylmalate dehydrogenase
- Tumor necrosis factor
- Tumor necrosis factor receptor
- Mannosidase
- Transthyretin
- Transport inhibitor response 1
- Transducin
- Nitrate reductase
- Nitroreductase
- Dihydroorotate dehydrogenase
- L-rhamnose isomerase
- TRAIL
- Estrogen-related receptor
- Inosine monophosphate dehydrogenase
- Survivin
- UDP-N-acetylglucosamine acyltransferase
- Haptoglobin receptor
- D-alanine-D-alanine ligase
- Glutaminyl cyclase
- Severin
- Carnitine palmitoyltransferase
- Isoaspartyl dipeptidase
- Thiaminase
- Acetylcholinesterase with OTMA
- D275P mutant of alcohol dehydrogenase from protozoa Entamoeba histolytica
- Ferripyoverdine receptor
- Fatty acid-binding protein
- Rho-associated protein kinase
- Endonuclease
- Collagenase (non-MMP)
- Epoxidase
- Ferrochelatase
- Elastase
- Tyrosinase
- N-acetylornithine carbamoyltransferase
- Ornithine carbamoyltransferase
- Pantothenate kinase
- Pantothenate synthetase
- Parvalbumin
- Cephalosporin acylase
- Dipeptidyl peptidase
- Farnesyltransferase
- Farnesyl diphosphate synthase
- Arginine repressor
- Transferrin
- Transketolase
- Dihydropteroate synthase
- Trichodiene synthase
- DAHP synthase
- Trehalulose synthase
- TRNA-guanine transglycosylase
- Cyclophilin
- Cutinase
- Trypanothione reductase
- Trypsin inhibitor
- Tryptase
- Tubulin tyrosine ligase
- Transaldolase
- Urokinase
- Undecaprenyl pyrophosphate synthase
- UDP-galactose 4-epimerase
- Uridine 5'-monophosphate synthase
- Arsenate reductase
- Rac
- Rho GTPase
- Carbamoyl phosphate synthetase
- Dedicator of cytokinesis protein
- Phosphoribosylaminoimidazole carboxylase
- Retinoid isomerohydrolase
- Calcium uptake protein 1
- Abscisic acid receptor
- Apoptosis-inducing factor
- Nucleolin
- Aldo-keto reductase
- SAICAR synthetase
- Prolactin receptor
- Siderocalin
- Latrophilin
- Folypolyglutamate synthase
- WD repeat-containing protein
- Xylosidase
- Uridylate kinase
- Penicillin-binding protein
- Pentaerythritol tetranitrate reductase
- Thymidine kinase
- Thymidylate kinase
- Tissue factor pathway inhibitor
- Thioredoxin Reductase
- Peptidyl-tRNA hydrolase
- Peroxiredoxin
- Phenylethanolamine N-methyltransferase
- Tetracycline repressor protein
- Phenylpyruvate decarboxylase
- Succinate-semialdehyde dehydrogenase
- Spermidine/spermine N-acetyltransferase
- Sulfotransferase
- Phosphomannomutase
- Strictosidine Synthase
- Phosphoenolpyruvate carboxykinase
- Phosphoribosyltransferase
- Phosphoserine aminotransferase
- Phosphoserine phosphatase
- Shikimate kinase
- Shikimate dehydrogenase
- Selectin
- Selenocysteine synthase
- Semaphorin
- Serine palmitoyltransferase
- SAM decarboxylase
- SAM synthetase
- S-adenosylhomocysteine hydrolase
- Plasmepsin
- RNA uridylyltransferase
- Ribosomal protein S6 kinase
- Poly(A) RNA polymerase protein Cid1
- Ribonucleotide reductase
- Phycocyanobilin:ferredoxin oxidoreductase
- Poly (ADP-ribose) glycohydrolase
- Rhomboid protease
- Rhodopsin kinase
- Retinol-binding protein
- Polyneuridine Aldehyde Esterase
- Retinoid X receptor
- Porphobilinogen synthase
- Retinoblastoma-binding protein
- Pyruvate dehydrogenase kinase
- Pyruvate-ferredoxin oxidoreductase
- Pyrroline-5-carboxylate dehydrogenase
- Purine nucleoside phosphorylase
- Proline utilization A
- Protein kinase C
- Nucleoside diphosphate kinase
- Formate dehydrogenase
- NAD synthase
- Nuclear transcription factor Y
- Methanol dehydrogenase
- Matriptase
- Manganese peroxidase
- Mandelate racemase
- MEP cytidylyltransferase
- Mandelate dehydrogenase
- Malate synthase
- Macrophage inhibitory factor
- Homocitrate synthase
- Hemagglutinin-esterase
- Guanylate kinase
- Granzyme
- Glycosylasparaginase
- Glutaryl-CoA dehydrogenase
- Glutaminase
- Glutamate racemase
- Glucuronidase
- Glucose-1-phosphate thymidylyltransferase
- Geranylgeranyl transferase
- Galactose mutarotase
- Ficolin
- Phosphoinositide phosphatase
- Ferredoxin thioredoxin reductase
- PcrH
- Exportin
- Exoenzyme
- Epoxide hydrolase
- Elongation factor
- DNA damage-binding protein
- DNA adenine methylase
- Glucose 6-phosphate dehydrogenase
- Diphthine synthase
- Cytochrome f
- Cullin
- Cruzain
- Complement C3
- Formyl-CoA transferase
- Ferric hydroxamate uptake receptor
- Enoylpyruvate transferase
- Enoyl-CoA hydratase
- Cholesterol oxidase
- Ceruloplasmin
- Calpain
- DXP reductoisomerase
- Diphtheria toxin
- Diphtheria toxin repressor
- Diguanylate cyclase
- Dehydroquinase
- Dehaloperoxidase
- Death-associated protein kinase
- D-aminoacylase
- Cytochrome c peroxidase
- Cytochrome b5
- Cyclohydrolase
- Cocaine esterase
- CotA laccase
- Colicin I receptor
- Choline O-acetyltransferase
- Choline kinase
- 5'-deoxy-5'-methylthioadenosine phosphorylase
- CD4
- Casein kinase
- Nitrile hydratase
- UDP-3-O-acyl-N-acetylglucosamine deacetylase
- Chitinase-3-like protein
- Insulin-like growth factor receptor
- Ribose-binding protein
- Nitrite reductase
- DNA methyltransferase
- Pre-mRNA-splicing factor
- Carboxylesterase
- Ankyrin
- Acetylcholinesterase with DFP
- IFG/DG-Cerezyme
- C-terminal portion of human eIF4GI
- Death Associated Protein 5
- Acetylcholinesterase complexed with N-9-(1',2',3',4'-tetrahydroacridinyl)-1,8-diaminooctane
- Torpedo californica acetylcholinesterase with alkylene-linked tacrine dimer (5 carbon linker)
- Thioredoxin Glutathione Reductase
- Journal:PMC:1